A menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia AV Krivtsov, K Evans, JY Gadrey, BK Eschle, C Hatton, HJ Uckelmann, ... Cancer cell 36 (6), 660-673. e11, 2019 | 334 | 2019 |
RAB27A promotes melanoma cell invasion and metastasis via regulation of pro‐invasive exosomes D Guo, GYL Lui, SL Lai, JS Wilmott, S Tikoo, LA Jackett, C Quek, ... International journal of cancer 144 (12), 3070-3085, 2019 | 97 | 2019 |
BloodChIP: a database of comparative genome-wide transcription factor binding profiles in human blood cells D Chacon, D Beck, D Perera, JWH Wong, JE Pimanda Nucleic acids research 42 (D1), D172-D177, 2014 | 50 | 2014 |
A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients D Beck, JAI Thoms, C Palu, T Herold, A Shah, J Olivier, L Boelen, ... Leukemia 32 (2), 263-272, 2018 | 41 | 2018 |
Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells JAI Thoms, P Truong, S Subramanian, K Knezevic, G Harvey, Y Huang, ... Blood, The Journal of the American Society of Hematology 138 (16), 1441-1455, 2021 | 39 | 2021 |
OncoCis: annotation of cis-regulatory mutations in cancer D Perera, D Chacon, JAI Thoms, RC Poulos, A Shlien, D Beck, ... Genome biology 15, 1-14, 2014 | 28 | 2014 |
Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs S Subramanian, JAI Thoms, Y Huang, P Cornejo-Páramo, FC Koch, ... Blood 142 (17), 1448-1462, 2023 | 20 | 2023 |
Voip networks performance analysis with encryption systems EP Guillen, DA Chacon World Academy of Science, Engineering and Technology 58, 688-6952009, 2009 | 17 | 2009 |
Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aorta V Chandrakanthan, P Rorimpandey, F Zanini, D Chacon, J Olivier, ... Nature Cell Biology 24 (8), 1211-1225, 2022 | 16 | 2022 |
Shared roles for Scl and Lyl1 in murine platelet production and function SK Chiu, SL Orive, MJ Moon, J Saw, S Ellis, BT Kile, Y Huang, D Chacon, ... Blood, The Journal of the American Society of Hematology 134 (10), 826-835, 2019 | 16 | 2019 |
Ancestry informative markers (AIMs) for Korean and other East Asian and south east asian populations JY Jung, PW Kang, E Kim, D Chacon, D Beck, D McNevin International Journal of Legal Medicine 133, 1711-1719, 2019 | 15 | 2019 |
Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine A Yeola, S Subramanian, RA Oliver, CA Lucas, JAI Thoms, F Yan, ... Science Advances 7 (3), eabd1929, 2021 | 6 | 2021 |
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response BA Pereira, S Ritchie, CR Chambers, KA Gordon, A Magenau, KJ Murphy, ... Science Advances 10 (27), eadl1197, 2024 | 2 | 2024 |
PU. 1 eviction at lymphocyte-specific chromatin domains mediates glucocorticoid response in acute lymphoblastic leukemia D Beck, H Cao, F Tian, Y Huang, M Jiang, H Zhao, X Tai, W Xu, ... Nature Communications 15 (1), 9697, 2024 | | 2024 |
Cell Type-Specific Regulation by a Heptad of Transcription Factors in Human Hematopoietic Stem and Progenitor Cells S Subramanian, JAI Thoms, Y Huang, P Cornejo, FC Koch, S Jacquelin, ... bioRxiv, 2023.04. 18.537282, 2023 | | 2023 |
Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions S Subramanian, JAI Thoms, Y Huang, S Jacquelin, S Shen, E Song, ... Blood 140 (Supplement 1), 2846-2848, 2022 | | 2022 |
Mesoderm-Derived PDGFRA+ Cells Regulate the Emergence of Hematopoietic Stem 2 Cells in the Dorsal Aorta B Gottgens Nature Research, 2022 | | 2022 |
3034–DISRUPTION OF A GATA2, TAL1, ERG REGULATORY CIRCUIT PROMOTES ERYTHROID TRANSITION IN HEALTHY AND LEUKEMIC STEM CELLS J Thoms, P Truong, S Subramanian, K Knezevic, G Harvey, Y Huang, ... Experimental Hematology 100, S59, 2021 | | 2021 |
Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk Stratification D Chacon, A Braytee, Y Huang, J Thoms, S Subramanian, MC Sauerland, ... Blood 134, 1397, 2019 | | 2019 |
Integrative analysis of lincRNA expression in 922 acute myeloid leukemia patients reveals multiple prognostic gene signatures D Beck, J Thoms, C Palu, T Herold, A Shah, J Olivier, L Boelen, Y Huang, ... Haematologica, 208-209, 2016 | | 2016 |