| The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton DA Canton, DW Litchfield Cellular signalling 18 (3), 267-275, 2006 | 137 | 2006 |
| Phosphorylation regulates the stability of the regulatory CK2β subunit C Zhang, G Vilk, DA Canton, DW Litchfield Oncogene 21 (23), 3754-3764, 2002 | 116 | 2002 |
| Phase II trial of IL-12 plasmid transfection and PD-1 blockade in immunologically quiescent melanoma AP Algazi, CG Twitty, KK Tsai, M Le, R Pierce, E Browning, R Hermiz, ... Clinical Cancer Research 26 (12), 2827-2837, 2020 | 105 | 2020 |
| The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein DA Canton, MEK Olsten, K Kim, A Doherty-Kirby, G Lajoie, JA Cooper, ... Molecular and cellular biology 25 (9), 3519-3534, 2005 | 89 | 2005 |
| The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane MEK Olsten, DA Canton, C Zhang, PA Walton, DW Litchfield Journal of Biological Chemistry 279 (40), 42114-42127, 2004 | 82 | 2004 |
| Functional specialization of CK2 isoforms and characterization of isoform-specific binding partners DW Litchfield, DG Bosc, DA Canton, RB Saulnier, G Vilk, C Zhang Molecular and cellular biochemistry 227, 21-29, 2001 | 76 | 2001 |
| Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory R Havekes, DA Canton, AJ Park, T Huang, T Nie, JP Day, LA Guercio, ... Journal of Neuroscience 32 (50), 18137-18149, 2012 | 72 | 2012 |
| Assembly of protein kinase CK2: investigation of complex formation between catalytic and regulatory subunits using a zinc-finger-deficient mutant of CK2β DA CANTON, C ZHANG, DW LITCHFIELD Biochemical Journal 358 (1), 87-94, 2001 | 69 | 2001 |
| Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc AA Paulucci-Holthauzen, LA Vergara, LJ Bellot, D Canton, JD Scott, ... Journal of biological chemistry 284 (9), 5956-5967, 2009 | 65 | 2009 |
| The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein DA Canton, MEK Olsten, H Niederstrasser, JA Cooper, DW Litchfield Journal of biological chemistry 281 (47), 36347-36359, 2006 | 58 | 2006 |
| Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy A Mukhopadhyay, J Wright, S Shirley, DA Canton, C Burkart, RJ Connolly, ... Gene therapy 26 (1), 1-15, 2019 | 54 | 2019 |
| A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells H Hehnly, D Canton, P Bucko, LK Langeberg, L Ogier, I Gelman, ... Elife 4, e09384, 2015 | 50 | 2015 |
| Melanoma treatment with intratumoral electroporation of tavokinogene telseplasmid (pIL-12, tavokinogene telseplasmid) DA Canton, S Shirley, J Wright, R Connolly, C Burkart, A Mukhopadhyay, ... Immunotherapy 9 (16), 1309-1321, 2017 | 49 | 2017 |
| Gravin is a transitory effector of polo-like kinase 1 during cell division DA Canton, CD Keene, K Swinney, LK Langeberg, V Nguyen, L Pelletier, ... Molecular Cell 48 (4), 547-559, 2012 | 45 | 2012 |
| Intratumoral Plasmid IL12 Expands CD8+ T Cells and Induces a CXCR3 Gene Signature in Triple-negative Breast Tumors that Sensitizes Patients to Anti–PD-1 … ML Telli, H Nagata, I Wapnir, CR Acharya, K Zablotsky, BA Fox, ... Clinical Cancer Research 27 (9), 2481-2493, 2021 | 38 | 2021 |
| Improving therapeutic efficacy of IL-12 intratumoral gene electrotransfer through novel plasmid design and modified parameters C Burkart, A Mukhopadhyay, SA Shirley, RJ Connolly, JH Wright, ... Gene therapy, 2018 | 36 | 2018 |
| ST-11: a new brain-penetrant microtubule-destabilizing agent with therapeutic potential for glioblastoma multiforme AE Cherry, BR Haas, AV Naydenov, S Fung, C Xu, K Swinney, ... Molecular cancer therapeutics 15 (9), 2018-2029, 2016 | 26 | 2016 |
| Anchoring proteins encounter mitotic kinases DA Canton, JD Scott Cell Cycle 12 (6), 863-864, 2013 | 13 | 2013 |
| Intratumoral electroporation of plasmid encoded IL12 and membrane-anchored anti-CD3 increases systemic tumor immunity M Han, B Nguyen, JY Lee, E Browning, J Zhang, A Mukhopadhyay, ... Molecular Cancer Research 20 (6), 983-995, 2022 | 9 | 2022 |
| 799 Durable responses and immune activation with intratumoral electroporation of pIL-12 plus pembrolizumab in actively progressing anti-PD-1 refractory advanced melanoma … P Fernandez-Penas, M Carlino, K Tsai, V Atkinson, M Shaheen, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 8 | 2020 |
David LitchfieldProfessor of Biochemistry & Professor of Oncology, Western University, London, Ontario, CANADADirección de correo verificada de uwo.ca
