| Chroman-4-one-and chromone-based sirtuin 2 inhibitors with antiproliferative properties in cancer cells T Seifert, M Malo, T Kokkola, K Engen, M Friden-Saxin, EAA Wallen, ... Journal of Medicinal Chemistry 57 (23), 9870-9888, 2014 | 109 | 2014 |
| Binding to and inhibition of insulin-regulated aminopeptidase by macrocyclic disulfides enhances spine density S Diwakarla, E Nylander, A Grönbladh, SR Vanga, YS Khan, ... Molecular pharmacology 89 (4), 413-424, 2016 | 46 | 2016 |
| Microwave heated flow synthesis of spiro-oxindole dihydroquinazolinone based IRAP inhibitors K Engen, J Savmarker, U Rosenstrom, J Wannberg, T Lundback, ... Organic Process Research & Development 18 (11), 1582-1588, 2014 | 45 | 2014 |
| Aryl sulfonamide inhibitors of insulin-regulated aminopeptidase enhance spine density in primary hippocampal neuron cultures S Diwakarla, E Nylander, A Gronbladh, SR Vanga, Y Shamsudin, ... ACS chemical neuroscience 7 (10), 1383-1392, 2016 | 34 | 2016 |
| Identification of drug-like inhibitors of insulin-regulated aminopeptidase through small-molecule screening K Engen, U Rosenström, H Axelsson, V Konda, L Dahllund, M Otrocka, ... Assay and drug development technologies 14 (3), 180-193, 2016 | 19 | 2016 |
| Virtual screening for transition state analogue inhibitors of IRAP based on quantum mechanically derived reaction coordinates F Svensson, K Engen, T Lundback, M Larhed, C Skold Journal of chemical information and modeling 55 (9), 1984-1993, 2015 | 13 | 2015 |
| MeONH2· HCl-Mediated α-Methylenation/Conjugate Addition of α-Sulfonyl o-Hydroxyacetophenones with Methyl Sulfoxides: Route to 3-Sulfonylchroman-4-ones MY Chang, KT Chen Synthesis 53 (01), 135-145, 2021 | 9 | 2021 |
| Synthesis, evaluation and proposed binding pose of substituted spiro‐oxindole dihydroquinazolinones as IRAP inhibitors K Engen, SR Vanga, T Lundbäck, F Agalo, V Konda, AJ Jensen, J Åqvist, ... ChemistryOpen 9 (3), 325-337, 2020 | 7 | 2020 |
| Microwave Chemistry P Cintas, P Veronesi, C Leonelli, G Keglevich, Z Mucsi, M Radoiu, ... Walter de Gruyter GmbH & Co KG, 2017 | 4 | 2017 |
| Inhibition of Insulin-Regulated Aminopeptidase by Imidazo [1, 5-α] pyridines—Synthesis and Evaluation K Engen, T Lundbäck, A Yadav, S Puthiyaparambath, U Rosenström, ... International Journal of Molecular Sciences 25 (5), 2516, 2024 | 1 | 2024 |
| 19 Microwave heating in medicinal chemistry K Engen, J Sävmarker, LR Odell, M Larhed Microwave Chemistry, 358, 0 | 1 | |
| Inhibitors Targeting Insulin-Regulated Aminopeptidase (IRAP): Identification, Synthesis and Evaluation K Engen Acta Universitatis Upsaliensis, 2020 | | 2020 |
| Identification of novel insulin-regulated aminopeptidase (IRAP) inhibitors by high throughput screening K Engen, T Lundback, F Svensson, U Rosenstrom, C Skold, M Hallberg, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |
Hugo Gutierrez-de-TeranAssociate Professor, Department of Cell and molecular biology, Uppsala UniversityVerified email at icm.uu.se
