| Structure of the adenosine-bound human adenosine A1 receptor–Gi complex CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ... Nature 558 (7711), 559-563, 2018 | 319 | 2018 |
| Structure of the adenosine A1 receptor reveals the basis for subtype selectivity A Glukhova, DM Thal, AT Nguyen, EA Vecchio, M Jörg, PJ Scammells, ... Cell 168 (5), 867-877. e13, 2017 | 274 | 2017 |
| Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia CJ Draper-Joyce, R Bhola, J Wang, A Bhattarai, ATN Nguyen, ... Nature 597 (7877), 571-576, 2021 | 92 | 2021 |
| Extracellular loop 2 of the adenosine A1 receptor has a key role in orthosteric ligand affinity and agonist efficacy ATN Nguyen, JA Baltos, T Thomas, TD Nguyen, LL Muñoz, KJ Gregory, ... Molecular Pharmacology 90 (6), 703-714, 2016 | 56 | 2016 |
| New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism EA Vecchio, JA Baltos, ATN Nguyen, A Christopoulos, PJ White, LT May British journal of pharmacology 175 (21), 4036-4046, 2018 | 54 | 2018 |
| Structural Basis for Binding of Allosteric Drug Leads in the Adenosine A1 Receptor Y Miao, A Bhattarai, ATN Nguyen, A Christopoulos, LT May Scientific reports 8 (1), 16836, 2018 | 53 | 2018 |
| AMP-Activated Protein Kinase (AMPK) Activation by Benzofurans and Coumestans Isolated from Erythrina abyssinica PH Nguyen, TNA Nguyen, TT Dao, HW Kang, DT Ndinteh, JT Mbafor, ... Journal of natural products 73 (4), 598-602, 2010 | 52 | 2010 |
| Role of the second extracellular loop of the adenosine A1 receptor on allosteric modulator binding, signaling, and cooperativity ATN Nguyen, EA Vecchio, T Thomas, TD Nguyen, L Aurelio, ... Molecular pharmacology 90 (6), 715-725, 2016 | 50 | 2016 |
| Influenza A (H1N1) neuraminidase inhibitors from Vitis amurensis TNA Nguyen, TT Dao, BT Tung, H Choi, E Kim, J Park, SIL Lim, WK Oh Food chemistry 124 (2), 437-443, 2011 | 49 | 2011 |
| Structure-activity analysis of biased agonism at the human adenosine A3 receptor JA Baltos, S Paoletta, ATN Nguyen, KJ Gregory, DK Tosh, ... Molecular pharmacology 90 (1), 12-22, 2016 | 43 | 2016 |
| Prenylated pterocarpans as bacterial neuraminidase inhibitors PH Nguyen, TNA Nguyen, KW Kang, DT Ndinteh, JT Mbafor, YR Kim, ... Bioorganic & medicinal chemistry 18 (9), 3335-3344, 2010 | 40 | 2010 |
| A Structure–Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists L Aurelio, JA Baltos, L Ford, ATN Nguyen, M Jorg, SM Devine, C Valant, ... Journal of medicinal chemistry 61 (5), 2087-2103, 2018 | 28 | 2018 |
| Novel Irreversible Agonists Acting at the A1 Adenosine Receptor M Jorg, A Glukhova, A Abdul-Ridha, EA Vecchio, ATN Nguyen, ... Journal of Medicinal Chemistry 59 (24), 11182-11194, 2016 | 27 | 2016 |
| α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes M Sato, BA Evans, AL Sandström, LY Chia, S Mukaida, B San Thai, ... Biochemical Pharmacology 148, 27-40, 2018 | 23 | 2018 |
| The application of artificial intelligence to accelerate G protein‐coupled receptor drug discovery ATN Nguyen, DTN Nguyen, HY Koh, J Toskov, W MacLean, A Xu, ... British Journal of Pharmacology, 2023 | 12 | 2023 |
| Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1 Receptor in Living Cells E Comeo, P Trinh, AT Nguyen, CJ Nowell, ND Kindon, M Soave, ... Journal of Medicinal Chemistry 64 (10), 6670-6695, 2021 | 7 | 2021 |
| Structure-based virtual screening discovers potent and selective adenosine A1 receptor antagonists P Matricon, ATN Nguyen, DD Vo, JA Baltos, M Jaiteh, A Luttens, ... European Journal of Medicinal Chemistry 257, 115419, 2023 | 6 | 2023 |
| Small molecule allosteric modulation of the adenosine A1 receptor ATN Nguyen, QL Tran, JA Baltos, SM McNeill, DTN Nguyen, LT May Frontiers in Endocrinology 14, 1184360, 2023 | 3 | 2023 |
| Targeting G protein‐coupled receptors for heart failure treatment BS Thai, LY Chia, ATN Nguyen, C Qin, RH Ritchie, DS Hutchinson, ... British Journal of Pharmacology, 2023 | 1 | 2023 |
| Examining the Role of the Linker in Bitopic N6-Substituted Adenosine Derivatives Acting as Biased Adenosine A1 Receptor Agonists JK Awalt, ATN Nguyen, TJ Fyfe, BS Thai, PJ White, A Christopoulos, ... Journal of Medicinal Chemistry 65 (13), 9076-9095, 2022 | 1 | 2022 |
