| New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2495 | 2010 |
| Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ... Nature genetics 42 (7), 579-589, 2010 | 2160 | 2010 |
| Parental origin of sequence variants associated with complex diseases A Kong, V Steinthorsdottir, G Masson, G Thorleifsson, P Sulem, ... Nature 462 (7275), 868-874, 2009 | 656 | 2009 |
| Voltage-gated ion channels in human pancreatic β-cells: electrophysiological characterization and role in insulin secretion M Braun, R Ramracheya, M Bengtsson, Q Zhang, J Karanauskaite, ... Diabetes 57 (6), 1618-1628, 2008 | 504 | 2008 |
| Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ... Cell metabolism 16 (4), 435-448, 2012 | 481 | 2012 |
| Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ... Diabetes 60 (10), 2624-2634, 2011 | 451 | 2011 |
| Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes–associated variants TJ Nicolson, EA Bellomo, N Wijesekara, MK Loder, JM Baldwin, ... Diabetes 58 (9), 2070-2083, 2009 | 444 | 2009 |
| The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in … NL Beer, ND Tribble, LJ McCulloch, C Roos, PRV Johnson, ... Human molecular genetics 18 (21), 4081-4088, 2009 | 429 | 2009 |
| A KATP Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans PE MacDonald, YZD Marinis, R Ramracheya, A Salehi, X Ma, ... PLoS biology 5 (6), e143, 2007 | 312 | 2007 |
| Familial persistent hyperinsulinemic hypoglycemia of infancy and mutations in the sulfonylurea receptor MJ Dunne, C Kane, RM Shepherd, JA Sanchez, RFL James, ... New England Journal of Medicine 336 (10), 703-706, 1997 | 293 | 1997 |
| Spatiotemporal analysis of human intestinal development at single-cell resolution D Fawkner-Corbett, A Antanaviciute, K Parikh, M Jagielowicz, AS Gerós, ... Cell 184 (3), 810-826. e23, 2021 | 290 | 2021 |
| Loss of functional KATP channels in pancreatic β–cells causes persistent hyperinsulinemic hypoglycemia of infancy C Kane, RM Shepherd, PE Squires, PRV Johnson, RFL James, PJ Milla, ... Nature medicine 2 (12), 1344-1347, 1996 | 283 | 1996 |
| Observations on radioactivity from the Chernobyl accident RS Cambray, PA Cawse, JA Garland, JAB Gibson, P Johnson, GNJ Lewis, ... Nucl. Energy 26 (2), 77-101, 1987 | 276 | 1987 |
| Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes AH Rosengren, M Braun, T Mahdi, SA Andersson, ME Travers, M Shigeto, ... Diabetes 61 (7), 1726-1733, 2012 | 268 | 2012 |
| γ-Aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic β-cells M Braun, R Ramracheya, M Bengtsson, A Clark, JN Walker, PR Johnson, ... Diabetes 59 (7), 1694-1701, 2010 | 259 | 2010 |
| Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes Q Zhang, R Ramracheya, C Lahmann, A Tarasov, M Bengtsson, O Braha, ... Cell metabolism 18 (6), 871-882, 2013 | 251 | 2013 |
| The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation M Cnop, SJ Hughes, M Igoillo-Esteve, MB Hoppa, F Sayyed, ... Diabetologia 53, 321-330, 2010 | 250 | 2010 |
| Lipotoxicity disrupts incretin-regulated human β cell connectivity DJ Hodson, RK Mitchell, EA Bellomo, G Sun, L Vinet, P Meda, D Li, WH Li, ... The Journal of clinical investigation 123 (10), 4182-4194, 2013 | 232 | 2013 |
| The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis M van de Bunt, KJ Gaulton, L Parts, I Moran, PR Johnson, CM Lindgren, ... PloS one 8 (1), e55272, 2013 | 231 | 2013 |
| Regulation of glucagon secretion by glucose: paracrine, intrinsic or both? JN Walker, R Ramracheya, Q Zhang, PRV Johnson, M Braun, P Rorsman Diabetes, Obesity and Metabolism 13, 95-105, 2011 | 210 | 2011 |
