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Neil  J. Ganem
Neil J. Ganem
Boston University School of Medicine
Dirección de correo verificada de bu.edu
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A mechanism linking extra centrosomes to chromosomal instability
NJ Ganem, SA Godinho, D Pellman
Nature 460 (7252), 278-282, 2009
15842009
DNA breaks and chromosome pulverization from errors in mitosis
K Crasta, NJ Ganem, R Dagher, AB Lantermann, EV Ivanova, Y Pan, ...
Nature 482 (7383), 53-58, 2012
13002012
Tetraploidy, aneuploidy and cancer
NJ Ganem, Z Storchova, D Pellman
Current opinion in genetics & development 17 (2), 157-162, 2007
8302007
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes
M Kwon, SA Godinho, NS Chandhok, NJ Ganem, A Azioune, M Thery, ...
Genes & development 22 (16), 2189-2203, 2008
7192008
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors
RL Flynn, KE Cox, M Jeitany, H Wakimoto, AR Bryll, NJ Ganem, F Bersani, ...
Science 347 (6219), 273-277, 2015
5122015
Cytokinesis failure triggers hippo tumor suppressor pathway activation
NJ Ganem, H Cornils, SY Chiu, KP O’Rourke, J Arnaud, D Yimlamai, ...
Cell 158 (4), 833-848, 2014
3852014
The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK
NJ Ganem, DA Compton
The Journal of cell biology 166 (4), 473-478, 2004
2682004
The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells
AL Manning, NJ Ganem, SF Bakhoum, M Wagenbach, L Wordeman, ...
Molecular biology of the cell 18 (8), 2970-2979, 2007
2582007
Efficient mitosis in human cells lacking poleward microtubule flux
NJ Ganem, K Upton, DA Compton
Current biology 15 (20), 1827-1832, 2005
2442005
Linking abnormal mitosis to the acquisition of DNA damage
NJ Ganem, D Pellman
Journal of Cell Biology 199 (6), 871-881, 2012
2422012
Mapping the methylome
EV Epigenomics
Cell Cycle 5 (2), 155-158, 2006
226*2006
Limiting the proliferation of polyploid cells
NJ Ganem, D Pellman
Cell 131 (3), 437-440, 2007
2062007
Whole-genome doubling confers unique genetic vulnerabilities on tumour cells
RJ Quinton, A DiDomizio, MA Vittoria, K Kotýnková, CJ Ticas, S Patel, ...
Nature 590 (7846), 492-497, 2021
1712021
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control
W Gan, X Dai, X Dai, J Xie, S Yin, J Zhu, C Wang, Y Liu, J Guo, M Wang, ...
Nature cell biology 22 (2), 246-256, 2020
682020
Identification of the kinase STK25 as an upstream activator of LATS signaling
S Lim, N Hermance, T Mudianto, HM Mustaly, IPM Mauricio, MA Vittoria, ...
Nature communications 10 (1), 1547, 2019
622019
Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors
AG Henssen, C Reed, E Jiang, HD Garcia, J von Stebut, IC MacArthur, ...
Science translational medicine 9 (414), eaam9078, 2017
602017
Nuclear envelope rupture drives genome instability in cancer
S Lim, RJ Quinton, NJ Ganem
Molecular biology of the cell 27 (21), 3210-3213, 2016
532016
Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes
A Russo, F Pacchierotti, D Cimini, NJ Ganem, A Genescà, AT Natarajan, ...
Environmental and molecular mutagenesis 56 (7), 563-580, 2015
382015
Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression
J Rhodes, A Amsterdam, T Sanda, LA Moreau, K McKenna, S Heinrichs, ...
Molecular and cellular biology 29 (21), 5911-5922, 2009
372009
2-cyano-3, 12-dioxooleana-1, 9 (11)-diene-28-oic acid disrupts microtubule polymerization: a possible mechanism contributing to apoptosis
RD Couch, NJ Ganem, M Zhou, VM Popov, T Honda, TD Veenstra, ...
Molecular pharmacology 69 (4), 1158-1165, 2006
252006
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Artículos 1–20