Glutathione transferases: a structural perspective A Oakley Drug metabolism reviews 43 (2), 138-151, 2011 | 479 | 2011 |
Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential MA Bogoyevitch, I Boehm, A Oakley, AJ Ketterman, RK Barr Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 89-101, 2004 | 345 | 2004 |
Glutathione transferases: new functions AJ Oakley Current opinion in structural biology 15 (6), 716-723, 2005 | 250 | 2005 |
The 2.0-Å crystal structure of eqFP611, a far red fluorescent protein from the sea anemone Entacmaea quadricolor J Petersen, PG Wilmann, T Beddoe, AJ Oakley, RJ Devenish, M Prescott, ... Journal of biological chemistry 278 (45), 44626-44631, 2003 | 220 | 2003 |
The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution AJ Oakley, ML Bello, A Battistoni, G Ricci, J Rossjohn, HO Villar, ... Journal of molecular biology 274 (1), 84-100, 1997 | 202 | 1997 |
Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site J Rossjohn, WJ McKinstry, AJ Oakley, D Verger, J Flanagan, ... Structure 6 (3), 309-322, 1998 | 192 | 1998 |
The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site) AJ Oakley, ML Bello, M Nuccetelli, AP Mazzetti, MW Parker Journal of molecular biology 291 (4), 913-926, 1999 | 178 | 1999 |
The 2.2 Å crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation M Prescott, M Ling, T Beddoe, AJ Oakley, S Dove, O Hoegh-Guldberg, ... Structure 11 (3), 275-284, 2003 | 169 | 2003 |
The Three-Dimensional Structure of the Human Pi Class Glutathione Transferase P1-1 in Complex with the Inhibitor Ethacrynic Acid and Its Glutathione Conjugate, AJ Oakley, J Rossjohn, M Lo Bello, AM Caccuri, G Federici, MW Parker Biochemistry 36 (3), 576-585, 1997 | 155 | 1997 |
A molecular mousetrap determines polarity of termination of DNA replication in E. coli MD Mulcair, PM Schaeffer, AJ Oakley, HF Cross, C Neylon, TM Hill, ... Cell 125 (7), 1309-1319, 2006 | 150 | 2006 |
DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs Z Yin, Y Wang, LR Whittell, S Jergic, M Liu, E Harry, NE Dixon, MJ Kelso, ... Chemistry & biology 21 (4), 481-487, 2014 | 135 | 2014 |
The identification and structural characterization of C7orf24 as γ-glutamyl cyclotransferase: an essential enzyme in the γ-glutamyl cycle AJ Oakley, T Yamada, D Liu, M Coggan, AG Clark, PG Board Journal of Biological Chemistry 283 (32), 22031-22042, 2008 | 133 | 2008 |
Identification, characterization and structure of a new Delta class glutathione transferase isoenzyme R Udomsinprasert, S Pongjaroenkit, J Wongsantichon, AJ Oakley, ... Biochemical Journal 388 (3), 763-771, 2005 | 132 | 2005 |
Crystal Structure of Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26 at 0.95 Å Resolution: Dynamics of Catalytic Residues, AJ Oakley, M Klvaňa, M Otyepka, Y Nagata, MCJ Wilce, J Damborský Biochemistry 43 (4), 870-878, 2004 | 123 | 2004 |
Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses AJ Oakley, S Barrett, TS Peat, J Newman, VA Streltsov, L Waddington, ... American Chemical Society, 2010 | 114 | 2010 |
The crystal structures of glutathione S‐transferases isozymes 1–3 and 1–4 from Anopheles dirus species B AJ Oakley, T Harnnoi, R Udomsinprasert, K Jirajaroenrat, AJ Ketterman, ... Protein Science 10 (11), 2176-2185, 2001 | 104 | 2001 |
Crystal and Solution Structures of the Helicase-binding Domain of Escherichia coli Primase*: o AJ Oakley, KV Loscha, PM Schaeffer, E Liepinsh, G Pintacuda, MCJ Wilce, ... Journal of Biological Chemistry 280 (12), 11495-11504, 2005 | 97 | 2005 |
Structural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the α/β-hydrolase fold RA Steiner, HJ Janssen, P Roversi, AJ Oakley, S Fetzner Proceedings of the National Academy of Sciences 107 (2), 657-662, 2010 | 91 | 2010 |
Three‐dimensional structure of (1,4)‐β‐d‐mannan mannanohydrolase from tomato fruit R Bourgault, AJ Oakley, JD Bewley, MCJ Wilce Protein Science 14 (5), 1233-1241, 2005 | 90 | 2005 |
Flexibility revealed by the 1.85 Å crystal structure of the β sliding-clamp subunit of Escherichia coli DNA polymerase III AJ Oakley, P Prosselkov, G Wijffels, JL Beck, MCJ Wilce, NE Dixon Acta Crystallographica Section D: Biological Crystallography 59 (7), 1192-1199, 2003 | 90 | 2003 |