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Michael D. Kessler
Michael D. Kessler
Regeneron Genetics Center
Dirección de correo verificada de regeneron.com - Página principal
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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ...
Nature 590 (7845), 290-299, 2021
13132021
Exome sequencing and analysis of 454,787 UK Biobank participants
JD Backman, AH Li, A Marcketta, D Sun, J Mbatchou, MD Kessler, ...
Nature 599 (7886), 628-634, 2021
4392021
A reference methylome database and analysis pipeline to facilitate integrative and comparative epigenomics
Q Song, B Decato, EE Hong, M Zhou, F Fang, J Qu, T Garvin, M Kessler, ...
PloS one 8 (12), e81148, 2013
3672013
The placebo effect: from concepts to genes
B Colagiuri, LA Schenk, MD Kessler, SG Dorsey, L Colloca
Neuroscience 307, 171-190, 2015
3112015
Evolutionary genomic dynamics of Peruvians before, during, and after the Inca Empire
DN Harris, W Song, AC Shetty, KS Levano, O Cáceres, C Padilla, V Borda, ...
Proceedings of the National Academy of Sciences 115 (28), E6526-E6535, 2018
1442018
Common and rare variant associations with clonal haematopoiesis phenotypes
MD Kessler, A Damask, S O’Keeffe, N Banerjee, D Li, K Watanabe, ...
Nature 612 (7939), 301-309, 2022
98*2022
Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry
MD Kessler, L Yerges-Armstrong, MA Taub, AC Shetty, K Maloney, ...
Nature communications 7 (1), 12521, 2016
88*2016
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population
MD Kessler, DP Loesch, JA Perry, NL Heard-Costa, D Taliun, BE Cade, ...
Proceedings of the National Academy of Sciences, 2020
642020
The evolution of polymorphic hybrid incompatibilities in house mice
EL Larson, D Vanderpool, BAJ Sarver, C Callahan, S Keeble, ...
Genetics 209 (3), 845-859, 2018
532018
Oxaliplatin-induced peripheral neuropathy and identification of unique severity groups in colorectal cancer
KA Griffith, S Zhu, M Johantgen, MD Kessler, C Renn, AS Beutler, ...
Journal of pain and symptom management 54 (5), 701-706. e1, 2017
492017
Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors
EF Davis-Marcisak, AA Fitzgerald, MD Kessler, L Danilova, EM Jaffee, ...
Genome medicine 13, 1-22, 2021
27*2021
Ten quick tips for deep learning in biology
BD Lee, A Gitter, CS Greene, S Raschka, F Maguire, AJ Titus, MD Kessler, ...
PLoS computational biology 18 (3), e1009803, 2022
252022
Evolutionary history of modern Samoans
DN Harris, MD Kessler, AC Shetty, DE Weeks, RL Minster, S Browning, ...
Proceedings of the National Academy of Sciences 117 (17), 9458-9465, 2020
242020
Effective population size does not predict codon usage bias in mammals
MD Kessler, MD Dean
Ecology and evolution 4 (20), 3887-3900, 2014
182014
Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences
MD Kessler, NW Bateman, TP Conrads, GL Maxwell, JC Dunning Hotopp, ...
Cancer 125 (12), 2076-2088, 2019
152019
Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia
AA Kogan, MJ Topper, AJ Dellomo, L Stojanovic, LJ McLaughlin, ...
Proceedings of the National Academy of Sciences 119 (27), e2123227119, 2022
102022
Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets
R Erbe, MD Kessler, AV Favorov, H Easwaran, DA Gaykalova, EJ Fertig
Nucleic Acids Research 48 (12), e68, 2020
82020
Improving cancer detection and treatment with liquid biopsies and ptDNA
MD Kessler, NR Pawar, SS Martin, TM Antalis, TD O’Connor
Trends in cancer 4 (9), 643-654, 2018
82018
Rare coding variants in CHRNB2 reduce the likelihood of smoking
VM Rajagopal, K Watanabe, J Mbatchou, A Ayer, P Quon, D Sharma, ...
Nature Genetics 55 (7), 1138-1148, 2023
62023
Accurate and equitable medical genomic analysis requires an understanding of demography and its influence on sample size and ratio
MD Kessler, TD O’Connor
Genome biology 18, 1-3, 2017
62017
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Artículos 1–20