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Chetan Seshadri
Chetan Seshadri
Assistant Professor of Medicine
Dirección de correo verificada de uw.edu
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Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection
JD Simmons, CM Stein, C Seshadri, M Campo, G Alter, S Fortune, ...
Nature Reviews Immunology 18 (9), 575-589, 2018
2672018
COMPASS identifies T-cell subsets correlated with clinical outcomes
L Lin, G Finak, K Ushey, C Seshadri, TR Hawn, N Frahm, TJ Scriba, ...
Nature biotechnology 33 (6), 610-616, 2015
2552015
IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure
LL Lu, MT Smith, KKQ Yu, C Luedemann, TJ Suscovich, PS Grace, A Cain, ...
Nature medicine 25 (6), 977-987, 2019
2082019
Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2
MG Drage, HC Tsai, ND Pecora, TY Cheng, AR Arida, S Shukla, ...
Nature structural & molecular biology 17 (9), 1088-1095, 2010
1582010
CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans
AG Kasmar, I van Rhijn, TY Cheng, M Turner, C Seshadri, A Schiefner, ...
Journal of Experimental Medicine 208 (9), 1741-1747, 2011
1382011
Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection
C Seshadri, N Sedaghat, M Campo, G Peterson, RD Wells, GS Olson, ...
PloS one 12 (4), e0175844, 2017
602017
A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis
C Seshadri, NTT Thuong, NTH Mai, ND Bang, TTH Chau, DM Lewinsohn, ...
Genes & Immunity 18 (1), 8-14, 2017
592017
Harnessing donor unrestricted T-cells for new vaccines against tuberculosis
SA Joosten, THM Ottenhoff, DM Lewinsohn, DF Hoft, DB Moody, ...
Vaccine 37 (23), 3022-3030, 2019
522019
A randomized, double-blinded, placebo-controlled, phase 1 study of a replication-defective herpes simplex virus (HSV) type 2 vaccine, HSV529, in adults with or without HSV …
LK Dropulic, MC Oestreich, HL Pietz, KJ Laing, S Hunsberger, K Lumbard, ...
The Journal of Infectious Diseases 220 (6), 990-1000, 2019
502019
Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2
KQ Krystle, S Fischinger, MT Smith, C Atyeo, D Cizmeci, CR Wolf, ...
JCI insight 6 (6), 2021
492021
Human CD1a deficiency is common and genetically regulated
C Seshadri, M Shenoy, RD Wells, T Hensley-McBain, E Andersen-Nissen, ...
The Journal of Immunology 191 (4), 1586-1593, 2013
432013
In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection
DC Young, E Layre, SJ Pan, A Tapley, J Adamson, C Seshadri, Z Wu, ...
Chemistry & biology 22 (4), 516-526, 2015
402015
A polymorphism in human CD1A is associated with susceptibility to tuberculosis
C Seshadri, NTT Thuong, NTB Yen, ND Bang, TTH Chau, GE Thwaites, ...
Genes & Immunity 15 (3), 195-198, 2014
352014
A diverse lipid antigen–specific TCR repertoire is clonally expanded during active tuberculosis
WS DeWitt, KKQ Yu, DB Wilburn, A Sherwood, M Vignali, CL Day, ...
The Journal of Immunology 201 (3), 888-896, 2018
322018
CD1b tetramers identify T cells that recognize natural and synthetic diacylated sulfoglycolipids from Mycobacterium tuberculosis
CA James, KQ Krystle, M Gilleron, J Prandi, VR Yedulla, ZZ Moleda, ...
Cell chemical biology 25 (4), 392-402. e14, 2018
282018
T cell responses against mycobacterial lipids and proteins are poorly correlated in South African adolescents
C Seshadri, L Lin, TJ Scriba, G Peterson, D Freidrich, N Frahm, ...
The Journal of Immunology 195 (10), 4595-4603, 2015
272015
Identification and visualization of multidimensional antigen‐specific T‐cell populations in polychromatic cytometry data
L Lin, J Frelinger, W Jiang, G Finak, C Seshadri, PA Bart, G Pantaleo, ...
Cytometry Part A 87 (7), 675-682, 2015
262015
Asymmetric synthesis and structure elucidation of a glycerophospholipid from Mycobacterium tuberculosis [S]
B Ter Horst, C Seshadri, L Sweet, DC Young, BL Feringa, DB Moody, ...
Journal of lipid research 51 (5), 1017-1022, 2010
262010
Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis
C Seshadri, MT Turner, DM Lewinsohn, D Moody, I Van Rhijn
The Journal of Immunology 190 (1), 278-284, 2013
252013
T cells specific for a mycobacterial glycolipid expand after intravenous bacillus Calmette–Guerin vaccination
ED Layton, S Barman, DB Wilburn, KKQ Yu, MT Smith, JD Altman, ...
The Journal of Immunology 206 (6), 1240-1250, 2021
222021
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