| Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin TR Caulfield, FC Fiesel, EL Moussaud-Lamodière, DFAR Dourado, ... PLoS computational biology 10 (11), e1003935, 2014 | 105 | 2014 |
| Mammalian cytosolic glutathione transferases. DF Dourado, PA Fernandes, MJ Ramos Current protein & peptide science 9 (4), 325-337, 2008 | 103 | 2008 |
| Glutathione transferase: New model for glutathione activation DFAR Dourado, PA Fernandes, B Mannervik, MJ Ramos Chemistry–A European Journal 14 (31), 9591-9598, 2008 | 86 | 2008 |
| Structural and functional impact of parkinson disease‐associated mutations in the E3 ubiquitin ligase parkin FC Fiesel, TR Caulfield, EL Moussaud‐Lamodière, K Ogaki, ... Human mutation 36 (8), 774-786, 2015 | 78 | 2015 |
| Rational Design of a (S)-Selective-Transaminase for Asymmetric Synthesis of (1S)-1-(1, 1′-biphenyl-2-yl) ethanamine DFAR Dourado, S Pohle, ATP Carvalho, DS Dheeman, JM Caswell, ... ACS Catalysis 6 (11), 7749-7759, 2016 | 65 | 2016 |
| A breakthrough on Amanita phalloides poisoning: an effective antidotal effect by polymyxin B J Garcia, VM Costa, ATP Carvalho, R Silvestre, JA Duarte, ... Archives of toxicology 89, 2305-2323, 2015 | 65 | 2015 |
| A multiscale approach to predicting affinity changes in protein–protein interfaces DFAR Dourado, SC Flores Proteins: Structure, Function, and Bioinformatics 82 (10), 2681-2690, 2014 | 63 | 2014 |
| Multidimensional epistasis and fitness landscapes in enzyme evolution W Zhang, DFAR Dourado, PA Fernandes, MJ Ramos, B Mannervik Biochemical Journal 445 (1), 39-46, 2012 | 43 | 2012 |
| Mechanism of glutathione transferase P1-1-catalyzed activation of the prodrug canfosfamide (TLK286, TELCYTA) DFAR Dourado, PA Fernandes, MJ Ramos, B Mannervik Biochemistry 52 (45), 8069-8078, 2013 | 33 | 2013 |
| A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate RK Koripella, M Holm, D Dourado, CS Mandava, S Flores, S Sanyal Scientific reports 5 (1), 12970, 2015 | 32 | 2015 |
| Glutathione transferase A1-1: catalytic importance of arginine 15 DFAR Dourado, PA Fernandes, B Mannervik, MJ Ramos The Journal of Physical Chemistry B 114 (4), 1690-1697, 2010 | 25 | 2010 |
| Why the flavin adenine dinucleotide (FAD) cofactor needs to be covalently linked to complex II of the electron‐transport chain for the conversion of FADH2 into FAD DFAR Dourado, M Swart, ATP Carvalho Chemistry–A European Journal 24 (20), 5246-5252, 2018 | 23 | 2018 |
| Glutathione transferase classes alpha, pi, and mu: GSH activation mechanism DFAR Dourado, PA Fernandes, MJ Ramos The journal of physical chemistry B 114 (40), 12972-12980, 2010 | 23 | 2010 |
| Isomerization of Δ5-Androstene-3,17-dione into Δ4-Androstene-3,17-dione Catalyzed by Human Glutathione Transferase A3-3: A Computational Study Identifies a … DFAR Dourado, PA Fernandes, B Mannervik, MJ Ramos The Journal of Physical Chemistry A 118 (31), 5790-5800, 2014 | 22 | 2014 |
| New in silico insights into the inhibition of RNAP II by α-amanitin and the protective effect mediated by effective antidotes J Garcia, ATP Carvalho, DFAR Dourado, P Baptista, M de Lourdes Bastos, ... Journal of Molecular Graphics and Modelling 51, 120-127, 2014 | 20 | 2014 |
| Modeling and fitting protein-protein complexes to predict change of binding energy DFAR Dourado, SC Flores Scientific reports 6 (1), 25406, 2016 | 19 | 2016 |
| SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations AS Gomes, H Ramos, S Gomes, JB Loureiro, J Soares, V Barcherini, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (1), 129440, 2020 | 16 | 2020 |
| Catalytic mechanism of Phenylacetone monooxygenases for non-native linear substrates: implications on rational engineering of BVMOs to expand the substrate specificity A Carvalho, D Dourado, T Skvortsov, M Deabreu, L Ferguson, D Quinn, ... Physical Chemistry Chemical Physics, 2017 | 14 | 2017 |
| Mechanism of phosphatidylglycerol activation catalyzed by prolipoprotein diacylglyceryl transferase W Singh, M Bilal, J McClory, D Dourado, D Quinn, TS Moody, I Sutcliffe, ... The Journal of Physical Chemistry B 123 (33), 7092-7102, 2019 | 12 | 2019 |
| Dynamic structure of NGF and proNGF complexed with p75NTR: pro-peptide effect AC Pimenta, DFAR Dourado, JM Martins, A Melo, ... Journal of chemical information and modeling 54 (7), 2051-2067, 2014 | 12 | 2014 |
Alexandra CarvalhoUniversity of Coimbra, CNC-Center for Neuroscience and Cell BiologyVerified email at icm.uu.se
