| Ligand-independent EGFR signaling G Guo, K Gong, B Wohlfeld, KJ Hatanpaa, D Zhao, AA Habib Cancer research 75 (17), 3436-3441, 2015 | 205 | 2015 |
| Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for … K Gong, W Li Free Radical Biology and Medicine 51 (12), 2259-2271, 2011 | 183 | 2011 |
| Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma K Gong, C Chen, Y Zhan, Y Chen, Z Huang, W Li Journal of Biological Chemistry 287 (42), 35576-35588, 2012 | 156 | 2012 |
| Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma C Liu, K Gong, X Mao, W Li International journal of cancer 129 (6), 1519-1531, 2011 | 150 | 2011 |
| CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells K Gong, J Xie, H Yi, W Li Biochemical Journal 443 (3), 735-746, 2012 | 126 | 2012 |
| C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer’s disease ZH Wang, K Gong, X Liu, Z Zhang, X Sun, ZZ Wei, SP Yu, ... Nature communications 9 (1), 1784, 2018 | 111 | 2018 |
| A TNF–JNK–Axl–ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma G Guo, K Gong, S Ali, N Ali, S Shallwani, KJ Hatanpaa, E Pan, B Mickey, ... Nature neuroscience 20 (8), 1074-1084, 2017 | 99 | 2017 |
| Synergistic antitumour activity of sorafenib in combination with tetrandrine is mediated by reactive oxygen species (ROS)/Akt signaling J Wan, T Liu, L Mei, J Li, K Gong, C Yu, W Li British journal of cancer 109 (2), 342-350, 2013 | 93 | 2013 |
| TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer K Gong, G Guo, DE Gerber, B Gao, M Peyton, C Huang, JD Minna, ... The Journal of clinical investigation 128 (6), 2500-2518, 2018 | 86 | 2018 |
| P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells Y Zhan, K Gong, C Chen, H Wang, W Li Free Radical Biology and Medicine 53 (3), 532-543, 2012 | 62 | 2012 |
| EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer K Gong, G Guo, N Panchani, ME Bender, DE Gerber, JD Minna, F Fattah, ... Nature cancer 1 (4), 394-409, 2020 | 61 | 2020 |
| Tumor necrosis factor in lung cancer: Complex roles in biology and resistance to treatment K Gong, G Guo, N Beckley, Y Zhang, X Yang, M Sharma, AA Habib Neoplasia 23 (2), 189-196, 2021 | 53 | 2021 |
| Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma K Gong, Z Zhang, Y Chen, HB Shu, W Li European journal of pharmacology 738, 142-152, 2014 | 47 | 2014 |
| Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma G Guo, K Gong, VT Puliyappadamba, N Panchani, E Pan, B Mukherjee, ... Neuro-oncology 21 (12), 1529-1539, 2019 | 27 | 2019 |
| C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis HM Hu, Y Chen, L Liu, CG Zhang, W Wang, K Gong, Z Huang, MX Guo, ... The FASEB Journal 27 (1), 163-173, 2013 | 21 | 2013 |
| Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom Y Song, K Gong, H Yan, W Hong, L Wang, Y Wu, W Li, W Li, Z Cao Journal of Biological Chemistry 289 (17), 11667-11680, 2014 | 16 | 2014 |
| Itraconazole exerts its antitumor effect in esophageal cancer by suppressing the HER2/AKT signaling pathway W Zhang, AS Bhagwath, Z Ramzan, TA Williams, I Subramaniyan, ... Molecular cancer therapeutics 20 (10), 1904-1915, 2021 | 15 | 2021 |
| EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation G Guo, K Gong, N Beckley, Y Zhang, X Yang, R Chkheidze, KJ Hatanpaa, ... Nature cell biology 24 (8), 1291-1305, 2022 | 13 | 2022 |
| Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids K Gong, G Guo, NA Beckley, X Yang, Y Zhang, DE Gerber, JD Minna, ... Nature communications 12 (1), 7014, 2021 | 7 | 2021 |
| EGFR LIGAND SHIFTS THE ROLE OF EGFR FROM ONCOGENE TO TUMOR SUPPRESSOR IN EGFR AMPLIFIED GLIOBLASTOMA G Guo, K Gong, N Beckley, Y Zhang, X Yang, A Nayab, A Habib NEURO-ONCOLOGY 24, 38-39, 2022 | | 2022 |
Gao GuoUniversity of Alabama at BirminghamVerified email at uabmc.edu
