|Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway|
VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ...
Nature 547 (7664), 453-457, 2017
|Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition|
MJ Hangauer, VS Viswanathan, MJ Ryan, D Bole, JK Eaton, A Matov, ...
Nature 551 (7679), 247-250, 2017
|MicroRNA‐328 is associated with (non‐small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration|
S Arora, AR Ranade, NL Tran, S Nasser, S Sridhar, RL Korn, JTD Ross, ...
International journal of cancer 129 (11), 2621-2631, 2011
|Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks|
JC Chen, MJ Alvarez, F Talos, H Dhruv, GE Rieckhof, A Iyer, KL Diefes, ...
Cell 159 (2), 402-414, 2014
|Intravenous delivery of camptothecin-loaded PLGA nanoparticles for the treatment of intracranial glioma|
KT Householder, DM DiPerna, EP Chung, GM Wohlleb, HD Dhruv, ...
International journal of pharmaceutics 479 (2), 374-380, 2015
|Evaluation of pre-analytical factors affecting plasma DNA analysis|
H Markus, T Contente-Cuomo, M Farooq, WS Liang, MJ Borad, ...
Scientific reports 8 (1), 1-10, 2018
|Reciprocal activation of transcription factors underlies the dichotomy between proliferation and invasion of glioma cells|
HD Dhruv, WSMD Winslow, B Armstrong, S Tuncali, J Eschbacher, ...
PloS one 8 (8), e72134, 2013
|TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance|
JC Loftus, H Dhruv, S Tuncali, J Kloss, Z Yang, CA Schumacher, B Cao, ...
Molecular Cancer Research 11 (8), 865-874, 2013
|Phase 0 trial of AZD1775 in first-recurrence glioblastoma patients|
N Sanai, J Li, J Boerner, K Stark, J Wu, S Kim, A Derogatis, S Mehta, ...
Clinical Cancer Research 24 (16), 3820-3828, 2018
|Bioresponsive Copolymers of Poly(N-isopropylacrylamide) with Enzyme-Dependent Lower Critical Solution Temperatures|
DJ Overstreet, HD Dhruv, BL Vernon
Biomacromolecules 11 (5), 1154-1159, 2010
|Protein insertion and patterning of PEG bearing Langmuir monolayers|
H Dhruv, R Pepalla, M Taveras, DW Britt
Biotechnology progress 22 (1), 150-155, 2006
|Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma|
RS McNeill, DA Canoutas, TJ Stuhlmiller, HD Dhruv, DM Irvin, RE Bash, ...
Neuro-oncology 19 (11), 1469-1480, 2017
|A novel interaction between Pyk2 and MAP4K4 is integrated with glioma cell migration|
JC Loftus, Z Yang, J Kloss, H Dhruv, NL Tran, DL Riggs
Journal of signal transduction 2013, 2013
|Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis|
H Dhruv, JC Loftus, P Narang, JL Petit, M Fameree, J Burton, G Tchegho, ...
Journal of Biological Chemistry 288 (45), 32261-32276, 2013
|FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion|
TG Whitsett, SPF Ensign, HD Dhruv, LJ Inge, P Kurywchak, KK Wolf, ...
Clinical & experimental metastasis 31 (6), 613-623, 2014
|Integrated genomic analysis of survival outliers in glioblastoma|
S Peng, H Dhruv, B Armstrong, B Salhia, C Legendre, J Kiefer, J Parks, ...
Neuro-oncology 19 (6), 833-844, 2017
|Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells|
A Roos, HD Dhruv, IT Mathews, LJ Inge, S Tuncali, LK Hartman, D Chow, ...
Oncotarget 8 (7), 12234, 2017
|Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation|
JB Bell, F Eckerdt, HD Dhruv, D Finlay, S Peng, S Kim, B Kroczynska, ...
Molecular Cancer Research 16 (1), 32-46, 2018
|SGEF is regulated via TWEAK/Fn14/NF-κB signaling and promotes survival by modulation of the DNA repair response to temozolomide|
SPF Ensign, A Roos, IT Mathews, HD Dhruv, S Tuncali, JN Sarkaria, ...
Molecular Cancer Research 14 (3), 302-312, 2016
|Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioblastoma cell chemotaxis via Lyn activation|
HD Dhruv, TG Whitsett, NM Jameson, F Patel, JA Winkles, ME Berens, ...
Carcinogenesis 35 (1), 218-226, 2014