The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells E Batlle, E Sancho, C Francí, D Domínguez, M Monfar, J Baulida, ... Nature cell biology 2 (2), 84-89, 2000 | 3298 | 2000 |
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells M Van de Wetering, E Sancho, C Verweij, W De Lau, I Oving, A Hurlstone, ... Cell 111 (2), 241-250, 2002 | 2527 | 2002 |
β-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB E Batlle, JT Henderson, H Beghtel, MMW Van den Born, E Sancho, ... Cell 111 (2), 251-263, 2002 | 1427 | 2002 |
Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation A Calon, E Espinet, S Palomo-Ponce, DVF Tauriello, M Iglesias, ... Cancer cell 22 (5), 571-584, 2012 | 1095 | 2012 |
The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse A Merlos-Suárez, FM Barriga, P Jung, M Iglesias, MV Céspedes, ... Cell stem cell 8 (5), 511-524, 2011 | 1060 | 2011 |
Stromal gene expression defines poor-prognosis subtypes in colorectal cancer A Calon, E Lonardo, A Berenguer-Llergo, E Espinet, ... Nature genetics 47 (4), 320-329, 2015 | 1059 | 2015 |
Isolation and in vitro expansion of human colonic stem cells P Jung, T Sato, A Merlos-Suárez, FM Barriga, M Iglesias, D Rossell, ... Nature medicine 17 (10), 1225-1227, 2011 | 762 | 2011 |
Signaling pathways in intestinal development and cancer E Sancho, E Batlle, H Clevers Annu. Rev. Cell Dev. Biol. 20, 695-723, 2004 | 705 | 2004 |
Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression andZEB1 expression S Guaita, I Puig, C Francı, M Garrido, D Domınguez, E Batlle, E Sancho, ... Journal of Biological Chemistry 277 (42), 39209-39216, 2002 | 591 | 2002 |
EphB receptor activity suppresses colorectal cancer progression E Batlle, J Bacani, H Begthel, S Jonkeer, A Gregorieff, M Van De Born, ... Nature 435 (7045), 1126-1130, 2005 | 511 | 2005 |
EphB–ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells C Cortina, S Palomo-Ponce, M Iglesias, JL Fernández-Masip, A Vivancos, ... Nature genetics 39 (11), 1376-1383, 2007 | 316 | 2007 |
Live and let die in the intestinal epithelium E Sancho, E Batlle, H Clevers Current opinion in cell biology 15 (6), 763-770, 2003 | 307 | 2003 |
Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc V Muncan, OJ Sansom, L Tertoolen, TJ Phesse, H Begthel, E Sancho, ... Molecular and cellular biology, 2006 | 303 | 2006 |
Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells C Ballaré, M Uhrig, T Bechtold, E Sancho, M Di Domenico, A Migliaccio, ... Molecular and cellular biology 23 (6), 1994-2008, 2003 | 278 | 2003 |
Role of UEV-1, an inactive variant of the E2 ubiquitinconjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29-M6 intestinal mucosecretory cells E Sancho, MR Vilá, L Sánchez-Pulido, JJ Lozano, R Paciucci, M Nadal, ... Molecular and Cellular Biology 18 (1), 576-589, 1998 | 179 | 1998 |
Overcoming TGFβ-mediated immune evasion in cancer DVF Tauriello, E Sancho, E Batlle Nature Reviews Cancer 22 (1), 25-44, 2022 | 156 | 2022 |
The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression G Whissell, E Montagni, P Martinelli, X Hernando-Momblona, M Sevillano, ... Nature Cell Biology 16 (7), 695-707, 2014 | 145 | 2014 |
A genome editing approach to study cancer stem cells in human tumors C Cortina, G Turon, D Stork, X Hernando‐Momblona, M Sevillano, ... EMBO molecular medicine 9 (7), 869-879, 2017 | 116 | 2017 |
Purification and Characterization of Active and Stable Recombinant Plasminogen‐Activator Inhibitor Accumulated at High Levels in Escherichia coli E Sancho, DW Tonge, RC Hockney, NA Booth European journal of biochemistry 224 (1), 125-134, 1994 | 81 | 1994 |
Conformational studies on plasminogen activator inhibitor (PAI-1) in active, latent, substrate, and cleaved forms E Sancho, PJ Declerck, NC Price, SM Kelly, NA Booth Biochemistry 34 (3), 1064-1069, 1995 | 74 | 1995 |