Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity AJ Davenport, RS Cross, KA Watson, Y Liao, W Shi, HM Prince, ... Proceedings of the National Academy of Sciences 115 (9), E2068-E2076, 2018 | 268 | 2018 |
Comparative molecular field analysis using GRID force-field and GOLPE variable selection methods in a study of inhibitors of glycogen phosphorylase b G Cruciani, KA Watson Journal of medicinal chemistry 37 (16), 2589-2601, 1994 | 198 | 1994 |
Potent inhibition of glycogen phosphorylase by a spirohydantoin of glucopyranose: First pyranose analogues of hydantocidin CJF Bichard, EP Mitchell, MR Wormald, KA Watson, LN Johnson, ... Tetrahedron letters 36 (12), 2145-2148, 1995 | 180 | 1995 |
Design of Inhibitors of Glycogen Phosphorylase: A Study of. alpha.-and. beta.-C-Glucosides and 1-Thio-. beta.-D-glucose Compounds KA Watson, EP Mitchell, LN Johnson, CJF Bichard, MG Orchard, ... Biochemistry 33 (19), 5745-5758, 1994 | 162 | 1994 |
The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 Å resolution and 100 K: The role of the water structure and its contribution to binding M Gregoriou, MEM Noble, KA Watson, EF Garman, LN Johnson, ... Protein Science 7 (4), 915-927, 1998 | 128 | 1998 |
A strategy for the incorporation of water molecules present in a ligand binding site into a three-dimensional quantitative structure− activity relationship analysis M Pastor, G Cruciani, KA Watson Journal of Medicinal Chemistry 40 (25), 4089-4102, 1997 | 126 | 1997 |
Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection KA Watson, EP Mitchell, LN Johnson, G Cruciani, JC Son, CJF Bichard, ... Acta Crystallographica Section D: Biological Crystallography 51 (4), 458-472, 1995 | 124 | 1995 |
Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question KA Watson, C McCleverty, S Geremia, S Cottaz, H Driguez, LN Johnson The EMBO journal 18 (17), 4619-4632, 1999 | 112 | 1999 |
The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor SE Zographos, NG Oikonomakos, KE Tsitsanou, DD Leonidas, ... Structure 5 (11), 1413-1425, 1997 | 112 | 1997 |
N‐acetyl‐β‐D‐glucopyranosylamine: A potent T‐state inhibitor of glycogen phosphorylase. A comparison with α‐D‐glucose NG Oikonomakos, M Kontou, SE Zographos, KA Watson, LN Johnson, ... Protein Science 4 (12), 2469-2477, 1995 | 93 | 1995 |
The crystal structure of Escherichia coli maltodextrin phosphorylase provides an explanation for the activity without control in this basic archetype of a phosphorylase KA Watson, R Schinzel, D Palm, LN Johnson The EMBO Journal 16 (1), 1-14, 1997 | 92 | 1997 |
Effect of sulphation on the oestrogen agonist activity of the phytoestrogens genistein and daidzein in MCF-7 human breast cancer cells D Pugazhendhi, KA Watson, S Mills, N Botting, GS Pope, PD Darbre The Journal of endocrinology 197 (3), 503, 2008 | 81 | 2008 |
Oligosaccharide substrate binding in Escherichia coli maltodextrin phosphorylase M O'Reilly, KA Watson, R Schinzel, D Palm, LN Johnson Nature structural biology 4 (5), 405-412, 1997 | 76 | 1997 |
EfeO-cupredoxins: major new members of the cupredoxin superfamily with roles in bacterial iron transport MB Rajasekaran, S Nilapwar, SC Andrews, KA Watson Biometals 23, 1-17, 2010 | 73 | 2010 |
Exploring quercetin and luteolin derivatives as antiangiogenic agents D Ravishankar, KA Watson, SY Boateng, RJ Green, F Greco, HMI Osborn European journal of medicinal chemistry 97, 259-274, 2015 | 67 | 2015 |
Specific inhibition of glycogen phosphorylase by a spirodiketopiperazine at the anomeric position of glucopyranose TM Krülle, KA Watson, M Gregoriou, LN Johnson, S Crook, DJ Watkin, ... Tetrahedron letters 36 (45), 8291-8294, 1995 | 63 | 1995 |
New approach to pharmacophore mapping and QSAR analysis using inductive logic programming. Application to thermolysin inhibitors and glycogen phosphorylase B inhibitors N Marchand-Geneste, KA Watson, BK Alsberg, RD King Journal of Medicinal Chemistry 45 (2), 399-409, 2002 | 60 | 2002 |
Whey-derived peptides interactions with ACE by molecular docking as a potential predictive tool of natural ACE inhibitors Y Chamata, KA Watson, P Jauregi International Journal of Molecular Sciences 21 (3), 864, 2020 | 53 | 2020 |
Is virtual reality a memorable experience in an educational context? T Nadan, V Alexandrov, R Jamieson, K Watson International Journal of Emerging Technologies in Learning (iJET) 6 (1), 53-57, 2011 | 53 | 2011 |
Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure KE Tsitsanou, NG Oikonomakos, SE Zographos, VT Skamnaki, ... Protein Science 8 (4), 741-749, 1999 | 47 | 1999 |