p38 MAP kinases: beyond the stress response AR Nebreda, A Porras Trends in biochemical sciences 25 (6), 257-260, 2000 | 732 | 2000 |
Essential role of p38α MAP kinase in placental but not embryonic cardiovascular development RH Adams, A Porras, G Alonso, M Jones, K Vintersten, S Panelli, ... Molecular cell 6 (1), 109-116, 2000 | 700 | 2000 |
Apoptosis by cisplatin requires p53 mediated p38α MAPK activation through ROS generation P Bragado, A Armesilla, A Silva, A Porras Apoptosis 12, 1733-1742, 2007 | 467 | 2007 |
p38α mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli A Porras, S Zuluaga, E Black, A Valladares, AM Alvarez, C Ambrosino, ... Molecular biology of the cell 15 (2), 922-933, 2004 | 331 | 2004 |
Differentiation of 3T3-L1 Fibroblasts to Adipocytes Induced by Transfection of ras Oncogenes M Benito, A Porras, AR Nebreda, E Santos Science 253 (5019), 565-568, 1991 | 222 | 1991 |
Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation J Font de Mora, A Porras, N Ahn, E Santos Molecular and cellular biology 17 (10), 6068-6075, 1997 | 219 | 1997 |
Notch-1 controls the expression of fatty acid-activated transcription factors and is required for adipogenesis C Garcés, MJ Ruiz-Hidalgo, JF de Mora, C Park, L Miele, J Goldstein, ... Journal of Biological Chemistry 272 (47), 29729-29734, 1997 | 188 | 1997 |
p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation K Ramsauer, I Sadzak, A Porras, A Pilz, AR Nebreda, T Decker, P Kovarik Proceedings of the National Academy of Sciences 99 (20), 12859-12864, 2002 | 169 | 2002 |
p38α mediates cell survival in response to oxidative stress via induction of antioxidant genes: effect on the p70S6K pathway Á Gutiérrez-Uzquiza, M Arechederra, P Bragado, JA Aguirre-Ghiso, ... Journal of Biological Chemistry 287 (4), 2632-2642, 2012 | 156 | 2012 |
The ras signaling pathway mimics insulin action on glucose transporter translocation. L Kozma, K Baltensperger, J Klarlund, A Porras, E Santos, MP Czech Proceedings of the National Academy of Sciences 90 (10), 4460-4464, 1993 | 119 | 1993 |
Met acts on Mdm2 via mTOR to signal cell survival during development A Moumen, S Patané, A Porras, R Dono, F Maina Oxford University Press for The Company of Biologists Limited 134 (7), 1443-1451, 2007 | 112 | 2007 |
Triiodothyronine Induces the Transcription of the Uncoupling Protein Gene and Stabilizes Its mRNA in Fetal Rat Brown Adipocyte Primary Cultures (∗) C Guerra, C Roncero, A Porras, M Fernández, M Benito Journal of Biological Chemistry 271 (4), 2076-2081, 1996 | 105 | 1996 |
Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen-activated protein kinase/90-kDa S6 kinase (MAPK/RSK) cascade in the insulin/Ras pathway of adipocytic … A Porras, K Muszynski, UR Rapp, E Santos Journal of Biological Chemistry 269 (17), 12741-12748, 1994 | 103 | 1994 |
TNF-α inhibits UCP-1 expression in brown adipocytes via ERKs: opposite effect of p38MAPK A Valladares, C Roncero, M Benito, A Porras FEBS letters 493 (1), 6-11, 2001 | 89 | 2001 |
Activation of Ras by insulin in 3T3 L1 cells does not involve GTPase-activating protein phosphorylation. A Porras, AR Nebreda, M Benito, E Santos Journal of Biological Chemistry 267 (29), 21124-21131, 1992 | 87 | 1992 |
Negative regulation of Akt activity by p38α MAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1 S Zuluaga, A Álvarez-Barrientos, A Gutiérrez-Uzquiza, M Benito, ... Cellular signalling 19 (1), 62-74, 2007 | 84 | 2007 |
p42/p44 mitogen-activated protein kinases activation is required for the insulin-like growth factor-I/insulin induced proliferation, but inhibits differentiation, in rat fetal … A Porras, AM Álvarez, A Valladares, M Benito Molecular endocrinology 12 (6), 825-834, 1998 | 84 | 1998 |
p38 mitogen-activated protein kinase mediates tumor necrosis factor-α-induced apoptosis in rat fetal brown adipocytes A Valladares, AM Álvarez, JJ Ventura, C Roncero, M Benito, A Porras Endocrinology 141 (12), 4383-4395, 2000 | 83 | 2000 |
Critical role of hydrogen peroxide signaling in the sequential activation of p38 MAPK and eNOS in laminar shear stress R Bretón-Romero, CG de Orduña, N Romero, FJ Sánchez-Gómez, ... Free Radical Biology and Medicine 52 (6), 1093-1100, 2012 | 77 | 2012 |
HGF/c-Met signaling promotes liver progenitor cell migration and invasion by an epithelial–mesenchymal transition-independent, phosphatidyl inositol-3 kinase-dependent pathway … A Suárez-Causado, D Caballero-Diaz, E Bertran, C Roncero, A Addante, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (10), 2453-2463, 2015 | 72 | 2015 |