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Natalia Marchenko
Natalia Marchenko
Verified email at stonybrook.edu
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Cited by
Year
Death signal-induced localization of p53 protein to mitochondria: a potential role in apoptotic signaling
ND Marchenko, A Zaika, UM Moll
Journal of Biological Chemistry 275 (21), 16202-16212, 2000
12282000
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking
JM Stommel, ND Marchenko, GS Jimenez, UM Moll, TJ Hope, GM Wahl
The EMBO journal 18 (6), 1660-1672, 1999
9871999
p53 opens the mitochondrial permeability transition pore to trigger necrosis
AV Vaseva, ND Marchenko, K Ji, SE Tsirka, S Holzmann, UM Moll
Cell 149 (7), 1536-1548, 2012
8062012
Monoubiquitylation promotes mitochondrial p53 translocation
ND Marchenko, S Wolff, S Erster, K Becker, UM Moll
The EMBO journal 26 (4), 923-934, 2007
3692007
SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis
D Li, ND Marchenko, UM Moll
Cell Death & Differentiation 18 (12), 1904-1913, 2011
3582011
p53 and Nur77/TR3–transcription factors that directly target mitochondria for cell death induction
UM Moll, N Marchenko, XK Zhang
Oncogene 25 (34), 4725-4743, 2006
3182006
Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells
D Li, ND Marchenko, R Schulz, V Fischer, T Velasco-Hernandez, F Talos, ...
Molecular Cancer Research 9 (5), 577-588, 2011
3172011
WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization
Y Tomita, N Marchenko, S Erster, A Nemajerova, A Dehner, C Klein, ...
Journal of Biological Chemistry 281 (13), 8600-8606, 2006
3012006
Overexpression of the wild type p73 gene in breast cancer tissues and cell lines
AI Zaika, S Kovalev, ND Marchenko, UM Moll
Cancer Research 59 (13), 3257-3263, 1999
2851999
Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis
W Hanel, N Marchenko, S Xu, S Xiaofeng Yu, W Weng, U Moll
Cell Death & Differentiation 20 (7), 898-909, 2013
2722013
Hypoxia death stimulus induces translocation of p53 protein to mitochondria: detection by immunofluorescence on whole cells
C Sansome, A Zaika, ND Marchenko, UM Moll
FEBS letters 488 (3), 110-115, 2001
2542001
A quantitative analysis of rate-limiting steps in the metastatic cascade using human-specific real-time polymerase chain reaction
A Zijlstra, R Mellor, G Panzarella, RT Aimes, JD Hooper, ND Marchenko, ...
Cancer research 62 (23), 7083-7092, 2002
2502002
Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines
S Kovalev, N Marchenko, S Swendeman, M LaQuaglia, UM Moll
Cell Growth and Differentiation-Publication American Association for Cancer …, 1998
1981998
Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of …
GN Marchenko, ND Marchenko, J Leng, AY Strongin
Biochemical Journal 363 (2), 253-262, 2002
1362002
Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-α3 binding
ND Marchenko, W Hanel, D Li, K Becker, N Reich, UM Moll
Cell Death & Differentiation 17 (2), 255-267, 2010
1282010
β-Catenin regulates the gene of MMP-26, a novel matrix metalloproteinase expressed both in carcinomas and normal epithelial cells
ND Marchenko, GN Marchenko, RN Weinreb, JD Lindsey, ...
The international journal of biochemistry & cell biology 36 (5), 942-956, 2004
1262004
Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression
R Schulz, ND Marchenko, L Holembowski, G Fingerle-Rowson, M Pesic, ...
Journal of Experimental Medicine 209 (2), 275-289, 2012
1232012
p53 loss-of-heterozygosity is a necessary prerequisite for mutant p53 stabilization and gain-of-function in vivo
EM Alexandrova, SA Mirza, S Xu, R Schulz-Heddergott, ND Marchenko, ...
Cell death & disease 8 (3), e2661-e2661, 2017
1122017
The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells
AV Vaseva, ND Marchenko, U Moll
Cell cycle 8 (11), 1711-1719, 2009
1022009
Cytoplasmically “sequestered” wild type p53 protein is resistant to Mdm2-mediated degradation
A Zaika, N Marchenko, UM Moll
Journal of Biological Chemistry 274 (39), 27474-27480, 1999
1001999
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