Rafa Fernandez-Leiro
Rafa Fernandez-Leiro
CNIO - Spanish National Cancer Research Centre | Ramón y Cajal Fellow
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Unravelling biological macromolecules with cryo-electron microscopy
R Fernandez-Leiro, SHW Scheres
Nature 537 (7620), 339, 2016
2052016
A pipeline approach to single-particle processing in RELION
R Fernandez-Leiro, SHW Scheres
Acta Crystallographica Section D: Structural Biology 73 (6), 496-502, 2017
1012017
Structural basis of specificity in tetrameric Kluyveromyces lactis β-galactosidase
Á Pereira-Rodríguez, R Fernández-Leiro, MI González-Siso, ME Cerdán, ...
Journal of structural biology 177 (2), 392-401, 2012
752012
Structure and organization of heteromeric AMPA-type glutamate receptors
B Herguedas, J García-Nafría, O Cais, R Fernández-Leiro, J Krieger, ...
Science 352 (6285), aad3873, 2016
732016
cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ
R Fernandez-Leiro, J Conrad, SHW Scheres, MH Lamers
Elife 4, e11134, 2015
442015
Secretion and properties of a hybrid Kluyveromyces lactis-Aspergillus niger β-galactosidase
ÁP Rodríguez, RF Leiro, MC Trillo, ME Cerdán, MIG Siso, M Becerra
Microbial cell factories 5 (1), 41, 2006
382006
Structural analysis of Saccharomyces cerevisiae α-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases
R Fernández-Leiro, Á Pereira-Rodríguez, ME Cerdán, M Becerra, ...
Journal of Biological Chemistry 285 (36), 28020-28033, 2010
352010
Self-correcting mismatches during high-fidelity DNA replication
R Fernandez-Leiro, J Conrad, JC Yang, SMV Freund, SHW Scheres, ...
Nature structural & molecular biology 24 (2), 140, 2017
252017
Ixr1p regulates oxygen-dependent HEM13 transcription
R Castro-Prego, M Lamas-Maceiras, P Soengas, R Fernández-Leiro, ...
FEMS yeast research 10 (3), 309-321, 2010
142010
Kluyveromyces lactis β-galactosidase crystallization using full-factorial experimental design
ÁP Rodríguez, RF Leiro, ME Cerdán, MIG Siso, MB Fernández
Journal of Molecular Catalysis B: Enzymatic 52, 178-182, 2008
132008
Architecture of the mycobacterial type VII secretion system
N Famelis, A Rivera-Calzada, G Degliesposti, M Wingender, N Mietrach, ...
Nature 576 (7786), 321-325, 2019
102019
Crystallization and preliminary X-ray crystallographic analysis of β-galactosidase from Kluyveromyces lactis
A Pereira-Rodriguez, R Fernandez-Leiro, MI Gonzalez Siso, ME Cerdán, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
82010
Emerging two-dimensional crystallization of cucurbit [8] uril complexes: From supramolecular polymers to nanofibers
J Barrio, J Liu, RA Brady, CSY Tan, S Chiodini, M Ricci, ...
Journal of the American Chemical Society 141 (36), 14021-14025, 2019
52019
Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM
H Muñoz-Hernández, M Pal, CF Rodríguez, R Fernandez-Leiro, ...
Science advances 5 (5), eaaw1616, 2019
52019
Dual function of Ixr1 in transcriptional regulation and recognition of cisplatin-DNA adducts is caused by differential binding through its two HMG-boxes
A Vizoso-Vázquez, M Lamas-Maceiras, R Fernández-Leiro, A Rico-Díaz, ...
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1860 (2), 256-269, 2017
52017
A pipeline approach to single-particle processing in RELION
R Fernandez-Leiro, S Scheres
BioRxiv, 078352, 2016
42016
Crystallization and preliminary X-ray diffraction data of α-galactosidase from Saccharomyces cerevisiae
R Fernández-Leiro, A Pereira-Rodriguez, ME Cerdán, M Becerra, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
42010
The cryo-EM Structure of Thermotoga maritima β-Galactosidase: Quaternary Structure Guides Protein Engineering
S Míguez Amil, E Jiménez-Ortega, M Ramírez-Escudero, ...
ACS Chemical Biology, 2019
22019
Generalized displacement of DNA-and RNA-binding factors mediates the toxicity of arginine-rich cell-penetrating peptides
V Lafarga, O Sirozh, I Díaz-López, M Hisaoka, E Zarzuela, J Boskovic, ...
bioRxiv, 441808, 2019
22019
Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin
MI Flydal, M Alcorlo-Pagés, FG Johannessen, S Martínez-Caballero, ...
Proceedings of the National Academy of Sciences 116 (23), 11229-11234, 2019
12019
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Artículos 1–20