Frequent BRG1/SMARCA4–inactivating mutations in human lung cancer cell lines PP Medina, OA Romero, T Kohno, LM Montuenga, R Pio, J Yokota, ... Human mutation 29 (5), 617-622, 2008 | 287 | 2008 |
MAX Inactivation in Small Cell Lung Cancer Disrupts MYC–SWI/SNF Programs and Is Synthetic Lethal with BRG1 OA Romero, M Torres-Diz, E Pros, S Savola, A Gomez, S Moran, C Saez, ... Cancer discovery 4 (3), 292-303, 2014 | 201 | 2014 |
The tumour suppressor and chromatin‐remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer OA Romero, F Setien, S John, P Gimenez‐Xavier, G Gómez‐López, ... EMBO molecular medicine 4 (7), 603-616, 2012 | 96 | 2012 |
The SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseases OA Romero, M Sanchez-Cespedes Oncogene 33 (21), 2681-2689, 2014 | 90 | 2014 |
BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways L Jubierre, A Soriano, L Planells-Ferrer, L París-Coderch, SP Tenbaum, ... Oncogene 35 (39), 5179-5190, 2016 | 85 | 2016 |
MET-Oncogenic and JAK2-Inactivating Alterations Are Independent Factors That Affect Regulation of PD-L1 Expression in Lung Cancer M Saigi, JJ Alburquerque-Bejar, A Mc Leer-Florin, C Pereira, E Pros, ... Clinical Cancer Research 24 (18), 4579-4587, 2018 | 84 | 2018 |
Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts C Ambrogio, FJ Carmona, A Vidal, M Falcone, P Nieto, OA Romero, ... Cancer research 74 (21), 5978-5988, 2014 | 35 | 2014 |
Expression inactivation of SMARCA4 by microRNAs in lung tumors IF Coira, EE Rufino-Palomares, OA Romero, P Peinado, C Metheetrairut, ... Human molecular genetics 24 (5), 1400-1409, 2015 | 32 | 2015 |
SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade OA Romero, A Vilarrubi, JJ Alburquerque-Bejar, A Gomez, A Andrades, ... Nature communications 12 (1), 4319, 2021 | 28 | 2021 |
New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2 B Pérez-Benavente, A Fathinajafabadi, L De la Fuente, C Gandía, ... Genome Biology 23 (1), 252, 2022 | 17 | 2022 |
Comprehensive analysis of SWI/SNF inactivation in lung adenocarcinoma cell models P Peinado, A Andrades, M Cuadros, MI Rodriguez, IF Coira, DJ Garcia, ... Cancers 12 (12), 3712, 2020 | 13 | 2020 |
The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells MC Lafita-Navarro, J Liaño-Pons, A Quintanilla, I Varela, R Blanco, ... Journal of Biological Chemistry 295 (7), 2001-2017, 2020 | 11 | 2020 |
MAX mutant small-cell lung cancers exhibit impaired activities of MGA-dependent noncanonical polycomb repressive complex P Llabata, M Torres-Diz, A Gomez, L Tomas-Daza, OA Romero, ... Proceedings of the National Academy of Sciences 118 (37), e2024824118, 2021 | 10 | 2021 |
Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming OA Romero, S Verdura, M Torres-Diz, A Gomez, S Moran, E Condom, ... Oncogene 36 (9), 1287-1296, 2017 | 9 | 2017 |
MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer JJ Alburquerque-Bejar, P Navajas-Chocarro, M Saigi, A Ferrero-Andres, ... Cell Reports Medicine 4 (4), 2023 | 5 | 2023 |
2O MET activation in lung cancer up-regulates PD-L1 expression independently of JAK-STAT pathway, promoting an immunosuppressive phenotype M Saigí, JJ Alburquerque-Béjar, A Mc Leer-Florin, C Pereira, E Pros, ... Journal of Thoracic Oncology 13 (4), S1-S2, 2018 | 1 | 2018 |
Epigenetic Events in Lung Cancer OA Romero, M Sanchez-Cespedes Advances in Radiation Oncology in Lung Cancer, 17-31, 2022 | | 2022 |
SWI/SNF inactivation vulnerability A Vilarrubi, F Setien, E Pros, PP Medina, A Gomez, A Villanueva, ... Cancer Research 82 (12_Supplement), 3277-3277, 2022 | | 2022 |
New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-ß2 B Pérez-Benavente, A Fathinajafabadi, C Gandía, A Martínez-Férriz, ... BioMed Central, 2022 | | 2022 |
Searching for genetic alterations that drive the capability of evading tumor immunosurveillance in lung cancer JJ Alburquerque-Bejar, M Saigi, E Pros, O Romero, ... Cancer Research 80 (16_Supplement), 998-998, 2020 | | 2020 |