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Walter K. Schmidt
Walter K. Schmidt
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Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect
MO Bergo, B Gavino, J Ross, WK Schmidt, C Hong, LV Kendall, A Mohr, ...
Proceedings of the National Academy of Sciences 99 (20), 13049-13054, 2002
5192002
Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage
WK Schmidt, A Tam, K Fujimura-Kamada, S Michaelis
Proceedings of the National Academy of Sciences 95 (19), 11175-11180, 1998
2681998
Ste6p Mutants Defective in Exit from the Endoplasmic Reticulum (ER) Reveal Aspects of an ER Quality Control Pathway inSaccharomyces cerevisiae
D Loayza, A Tam, WK Schmidt, S Michaelis
Molecular biology of the cell 9 (10), 2767-2784, 1998
1551998
The Saccharomyces cerevisiae Prenylcysteine Carboxyl Methyltransferase Ste14p Is in the Endoplasmic Reticulum Membrane
JD Romano, WK Schmidt, S Michaelis
Molecular biology of the cell 9 (8), 2231-2247, 1998
1461998
Biochemical studies of Zmpste24-deficient mice
GK Leung, WK Schmidt, MO Bergo, B Gavino, DH Wong, A Tam, ...
Journal of Biological Chemistry 276 (31), 29051-29058, 2001
1122001
The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor
A Tam, WK Schmidt, S Michaelis
Journal of Biological Chemistry 276 (50), 46798-46806, 2001
852001
Ionic milieu controls the compartment-specific activation of pro-opiomelanocortin processing in AtT-20 cells.
WK Schmidt, HP Moore
Molecular biology of the cell 6 (10), 1271-1285, 1995
821995
Small-molecule inhibitors of the Rce1p CaaX protease
SP Manandhar, ER Hildebrandt, WK Schmidt
Journal of biomolecular screening 12 (7), 983-993, 2007
782007
Reconstitution of the Ste24p-dependent N-terminal proteolytic step in yeast a-factor biogenesis
WK Schmidt, A Tam, S Michaelis
Journal of biological chemistry 275 (9), 6227-6233, 2000
652000
8-Hydroxyquinoline-based inhibitors of the Rce1 protease disrupt Ras membrane localization in human cells
I Mohammed, SE Hampton, L Ashall, ER Hildebrandt, RA Kutlik, ...
Bioorganic & medicinal chemistry 24 (2), 160-178, 2016
582016
Mutational analysis of the ras converting enzyme reveals a requirement for glutamate and histidine residues
LJ Plummer, ER Hildebrandt, SB Porter, VA Rogers, J McCracken, ...
Journal of Biological Chemistry 281 (8), 4596-4605, 2006
572006
AtFACE-2, a functional prenylated protein protease from Arabidopsis thaliana related to mammalian Ras-converting enzymes
J Cadiñanos, I Varela, DA Mandel, WK Schmidt, A Díaz-Perales, ...
Journal of Biological Chemistry 278 (43), 42091-42097, 2003
552003
Rce1: mechanism and inhibition
SE Hampton, TM Dore, WK Schmidt
Critical reviews in biochemistry and molecular biology 53 (2), 157-174, 2018
532018
The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export
CJ Ketchum, WK Schmidt, GV Rajendrakumar, S Michaelis, PC Maloney
Journal of Biological Chemistry 276 (31), 29007-29011, 2001
502001
Inhibition of the CaaX proteases Rce1p and Ste24p by peptidyl (acyloxy) methyl ketones
SB Porter, ER Hildebrandt, SR Breevoort, DZ Mokry, TM Dore, ...
Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1773 (6), 853-862, 2007
492007
Efficient farnesylation of an extended C-terminal C (x) 3X sequence motif expands the scope of the prenylated proteome
MJ Blanden, KF Suazo, ER Hildebrandt, DS Hardgrove, M Patel, ...
Journal of Biological Chemistry 293 (8), 2770-2785, 2018
452018
Anion activation site of insulin-degrading enzyme
N Noinaj, ES Song, S Bhasin, BJ Alper, WK Schmidt, LB Hersh, ...
Journal of biological chemistry 287 (1), 48-57, 2012
352012
Chemical inhibition of CaaX protease activity disrupts yeast Ras localization
SP Manandhar, ER Hildebrandt, WH Jacobsen, GM Santangelo, ...
Yeast 27 (6), 327-343, 2010
342010
A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes
ER Hildebrandt, M Cheng, P Zhao, JH Kim, L Wells, WK Schmidt
Elife 5, e15899, 2016
322016
Yeast as a tractable genetic system for functional studies of the insulin-degrading enzyme
S Kim, AN Lapham, CGK Freedman, TL Reed, WK Schmidt
Journal of Biological Chemistry 280 (30), 27481-27490, 2005
322005
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Artículos 1–20