Biosynthesis of a biologically active single peptide chain containing the human common alpha and chorionic gonadotropin beta subunits in tandem T Sugahara, MR Pixley, S Minami, E Perlas, D Ben-Menahem, AJ Hsueh, ... Proceedings of the National Academy of Sciences 92 (6), 2041-2045, 1995 | 137 | 1995 |
Glycoprotein hormone structure-function and analog design. I Boime, D Ben-Menahem Recent progress in hormone research 54, 271-88; discussion 288, 1999 | 105 | 1999 |
Expression of Biologically Active Fusion Genes Encoding the Common Subunit and the Follicle-stimulating Hormone Subunit ROLE OF A LINKER SEQUENCE T Sugahara, A Sato, M Kudo, D Ben-Menahem, MR Pixley, AJW Hsueh, ... Journal of Biological Chemistry 271 (18), 10445-10448, 1996 | 94* | 1996 |
Cystine knot of the gonadotropin α subunit is critical for intracellular behavior but not for in vitro biological activity A Sato, E Perlas, D Ben-Menahem, M Kudo, MR Pixley, M Furuhashi, ... Journal of Biological Chemistry 272 (29), 18098-18103, 1997 | 60 | 1997 |
Regulation of gonadotropin mRNA levels in cultured rat pituitary cells by gonadotropin-releasing hormone (GnRH): role for Ca2+ and protein kinase C D Ben-Menahem, Z Naor Biochemistry 33 (12), 3698-3704, 1994 | 60 | 1994 |
Expression of biologically active fusion genes encoding the common α subunit and either the CGβ or FSHβ subunits: role of a linker sequence T Sugahara, PDJ Grootenhuis, A Sato, M Kudo, D Ben-Menahem, ... Molecular and cellular endocrinology 125 (1-2), 71-77, 1996 | 55 | 1996 |
Single chain glycoprotein hormones comprising two β and one α subunits and recombinant production thereof I Boime, DB Menahem US Patent 6,103,501, 2000 | 47 | 2000 |
Genetic fusion of an α-subunit gene to the follicle-stimulating hormone and chorionic gonadotropin-β subunit genes: production of a bifunctional protein M Kanda, A Jablonka-Shariff, A Sato, MR Pixley, E Bos, T Hiro’oka, ... Molecular Endocrinology 13 (11), 1873-1881, 1999 | 47 | 1999 |
The biologic action of single-chain choriogonadotropin is not dependent on the individual disulfide bonds of the β subunit D Ben-Menahem, M Kudo, MR Pixley, A Sato, N Suganuma, E Perlas, ... Journal of Biological Chemistry 272 (11), 6827-6830, 1997 | 46 | 1997 |
Conversion of thyrotropin heterodimer to a biologically active single-chain FA Fares, S Yamabe, D Ben-Menahem, M Pixley, AJW Hsueh, I Boime Endocrinology 139 (5), 2459-2464, 1998 | 39 | 1998 |
Activation of protein kinase C beta gene expression by gonadotropin-releasing hormone in alpha T3-1 cell line. Role of Ca2+ and autoregulation by protein kinase C. Z Shraga-Levine, D Ben-Menahem, Z Naor Journal of Biological Chemistry 269 (49), 31028-31033, 1994 | 37 | 1994 |
Single-chain β subunit dimers of the glycoprotein hormones and recombinant materials related thereto I Boime, D Ben-Menahem US Patent 5,958,737, 1999 | 36 | 1999 |
Cytosolic phospholipase A2α is targeted to the p47phox-PX domain of the assembled NADPH oxidase via a novel binding site in its C2 domain Z Shmelzer, M Karter, M Eisenstein, TL Leto, N Hadad, D Ben-Menahem, ... Journal of Biological Chemistry 283 (46), 31898-31908, 2008 | 32 | 2008 |
A conformational contribution of the luteinizing hormone–receptor ectodomain to receptor activation P Nurwakagari, A Breit, C Hess, H Salman-Livny, D Ben-Menahem, ... Journal of molecular endocrinology 38 (2), 259-275, 2007 | 32 | 2007 |
Arachidonic acid and Lipoxygenase Products Stimulate Gonadotropin. alpha.-Subunit mRNA Levels in Pituitary. alpha. T3-1 Cell Line: Role in Gonadotropin Releasing Hormone Action D Ben-Menahem, Z Shraga-Levine, R Limor, Z Naor Biochemistry 33 (43), 12795-12799, 1994 | 32 | 1994 |
Mechanism of action of gonadotropin-releasing hormone upon gonadotropin α-subunit mRNA levels in the α T3-1 cell line: role of Ca2+ and protein kinase C D Ben-Menahem, Z Shraga-Levine, PL Mellon, Z Naor Biochemical journal 309 (1), 325-329, 1995 | 30 | 1995 |
Mechanism of action of gonadotropin-releasing hormone upon gonadotropin -subunit mRNA levels in the T3-1 cell line: role of Ca^ 2^+ and protein kinase C D Ben-Menahem, Z Shraga-Levine, PL Mellon, Z Naor BIOCHEMICAL JOURNAL-LONDON- 309, 325-325, 1995 | 30* | 1995 |
Converting heterodimeric gonadotropins to genetically linked single chains: new approaches to structure activity relationships and analogue design D Ben-Menahem, I Boime Trends in Endocrinology & Metabolism 7 (3), 100-105, 1996 | 29 | 1996 |
Developmental expression of protein kinase C subspecies in rat brain-pituitary axis S Garcia-Navarro, Y Marantz, R Eyal, M Kalina, MH Disatnik, ... Molecular and cellular endocrinology 103 (1-2), 133-138, 1994 | 24 | 1994 |
The LHβ gene of several mammals embeds a carboxyl-terminal peptide-like sequence revealing a critical role for mucin oligosaccharides in the evolution of lutropin to chorionic … S Nakav, A Jablonka-Shariff, S Kaner, P Chadna-Mohanty, HE Grotjan, ... Journal of Biological Chemistry 280 (17), 16676-16684, 2005 | 23 | 2005 |