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The structural basis of cyclic diguanylate signal transduction by PilZ domains J Benach, SS Swaminathan, R Tamayo, SK Handelman, ... The EMBO journal 26 (24), 5153-5166, 2007 | 284 | 2007 |
Molecular insights into substrate recognition and catalysis by tryptophan 2, 3-dioxygenase F Forouhar, JLR Anderson, CG Mowat, SM Vorobiev, A Hussain, ... Proceedings of the National Academy of Sciences 104 (2), 473-478, 2007 | 207 | 2007 |
Expression system for structural and functional studies of human glycosylation enzymes KW Moremen, A Ramiah, M Stuart, J Steel, L Meng, F Forouhar, HA Moniz, ... Nature chemical biology 14 (2), 156-162, 2018 | 194 | 2018 |
Computational design of catalytic dyads and oxyanion holes for ester hydrolysis F Richter, R Blomberg, SD Khare, G Kiss, AP Kuzin, AJT Smith, J Gallaher, ... Journal of the American Chemical Society 134 (39), 16197-16206, 2012 | 184 | 2012 |
UNC119 is required for G protein trafficking in sensory neurons H Zhang, R Constantine, S Vorobiev, Y Chen, J Seetharaman, YJ Huang, ... Nature neuroscience 14 (7), 874-880, 2011 | 179 | 2011 |
Identification of the ice-binding surface on a type III antifreeze protein with a “flatness function” algorithm DSC Yang, WC Hon, S Bubanko, Y Xue, J Seetharaman, CL Hew, ... Biophysical journal 74 (5), 2142-2151, 1998 | 168 | 1998 |
Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus–host interaction S Li, X Tang, J Seetharaman, C Yang, Y Gu, J Zhang, H Du, JWK Shih, ... PLoS pathogens 5 (8), e1000537, 2009 | 165 | 2009 |
Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations BA Webb, F Forouhar, FE Szu, J Seetharaman, L Tong, DL Barber Nature 523 (7558), 111-114, 2015 | 149 | 2015 |
Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis DC Lohman, F Forouhar, ET Beebe, MS Stefely, CE Minogue, A Ulbrich, ... Proceedings of the National Academy of Sciences 111 (44), E4697-E4705, 2014 | 135 | 2014 |
Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases F Forouhar, S Arragain, M Atta, S Gambarelli, JM Mouesca, M Hussain, ... Nature chemical biology 9 (5), 333-338, 2013 | 135 | 2013 |
Enzymatic basis for N-glycan sialylation: structure of rat α2, 6-sialyltransferase (ST6GAL1) reveals conserved and unique features for glycan sialylation L Meng, F Forouhar, D Thieker, Z Gao, A Ramiah, H Moniz, Y Xiang, ... Journal of Biological Chemistry 288 (48), 34680-34698, 2013 | 129 | 2013 |
Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy JH Mills, SD Khare, JM Bolduc, F Forouhar, VK Mulligan, S Lew, ... Journal of the American Chemical Society 135 (36), 13393-13399, 2013 | 129 | 2013 |
Computational design of a protein-based enzyme inhibitor E Procko, R Hedman, K Hamilton, J Seetharaman, SJ Fleishman, M Su, ... Journal of molecular biology 425 (18), 3563-3575, 2013 | 114 | 2013 |
Structure and Evolutionary Origin of Ca2+-Dependent Herring Type II Antifreeze Protein Y Liu, Z Li, Q Lin, J Kosinski, J Seetharaman, JM Bujnicki, J Sivaraman, ... PLoS One 2 (6), e548, 2007 | 105 | 2007 |
A general computational approach for repeat protein design F Parmeggiani, PS Huang, S Vorobiev, R Xiao, K Park, S Caprari, M Su, ... Journal of molecular biology 427 (2), 563-575, 2015 | 96 | 2015 |
Computational design of enone-binding proteins with catalytic activity for the Morita–Baylis–Hillman reaction S Bjelic, LG Nivón, N Çelebi-Ölçüm, G Kiss, CF Rosewall, ... ACS chemical biology 8 (4), 749-757, 2013 | 96 | 2013 |
Design of activated serine–containing catalytic triads with atomic-level accuracy S Rajagopalan, C Wang, K Yu, AP Kuzin, F Richter, S Lew, AE Miklos, ... Nature chemical biology 10 (5), 386-391, 2014 | 88 | 2014 |
Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2, 3-dioxygenase A Lewis-Ballester, F Forouhar, SM Kim, S Lew, YQ Wang, S Karkashon, ... Scientific reports 6 (1), 35169, 2016 | 80 | 2016 |
Structural basis for the interaction of unstructured neuron specific substrates neuromodulin and neurogranin with Calmodulin V Kumar, VPR Chichili, L Zhong, X Tang, A Velazquez-Campoy, FS Sheu, ... Scientific reports 3 (1), 1392, 2013 | 79 | 2013 |