| Wnt signaling in cancer T Zhan, N Rindtorff, M Boutros Oncogene 36 (11), 1461-1473, 2017 | 2474 | 2017 |
| CRISPR/Cas9 for cancer research and therapy T Zhan, N Rindtorff, J Betge, MP Ebert, M Boutros Seminars in cancer biology 55, 106-119, 2019 | 316 | 2019 |
| Pooled in vitro and in vivo CRISPR-Cas9 screening identifies tumor suppressors in human colon organoids BE Michels, MH Mosa, BI Streibl, T Zhan, C Menche, K Abou-El-Ardat, ... Cell Stem Cell 26 (5), 782-792. e7, 2020 | 148 | 2020 |
| MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer T Zhan, G Ambrosi, AM Wandmacher, B Rauscher, J Betge, N Rindtorff, ... Nature communications 10 (1), 2197, 2019 | 141 | 2019 |
| The diagnosis and treatment of minimal hepatic encephalopathy T Zhan, W Stremmel Deutsches Ärzteblatt International 109 (10), 180, 2012 | 132 | 2012 |
| Silybin and dehydrosilybin decrease glucose uptake by inhibiting GLUT proteins T Zhan, M Digel, EM Küch, W Stremmel, J Füllekrug Journal of cellular biochemistry 112 (3), 849-859, 2011 | 124 | 2011 |
| CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries F Heigwer, T Zhan, M Breinig, J Winter, D Brügemann, S Leible, ... Genome biology 17, 1-10, 2016 | 87 | 2016 |
| Overexpressed FATP1, ACSVL4/FATP4 and ACSL1 increase the cellular fatty acid uptake of 3T3-L1 adipocytes but are localized on intracellular membranes T Zhan, M Poppelreuther, R Ehehalt, J Füllekrug Public Library of Science 7 (9), e45087, 2012 | 86 | 2012 |
| caRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens J Winter, M Breinig, F Heigwer, D Brügemann, S Leible, O Pelz, T Zhan, ... Bioinformatics 32 (4), 632-634, 2016 | 62 | 2016 |
| Prognostic cancer gene expression signatures: current status and challenges Y Qian, J Daza, T Itzel, J Betge, T Zhan, F Marmé, A Teufel Cells 10 (3), 648, 2021 | 58 | 2021 |
| Towards a compendium of essential genes–from model organisms to synthetic lethality in cancer cells T Zhan, M Boutros Critical reviews in biochemistry and molecular biology 51 (2), 74-85, 2016 | 58 | 2016 |
| Management of immune related adverse events induced by immune checkpoint inhibition A Teufel, T Zhan, N Härtel, J Bornschein, MP Ebert, N Schulte Cancer Letters 456, 80-87, 2019 | 47 | 2019 |
| CRISPRAnalyzeR: Interactive analysis, annotation and documentation of pooled CRISPR screens J Winter, M Schwering, O Pelz, B Rauscher, T Zhan, F Heigwer, M Boutros BioRxiv, 109967, 2017 | 47 | 2017 |
| Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples J Betge, G Kerr, T Miersch, S Leible, G Erdmann, CL Galata, T Zhan, ... PLoS One 10 (5), e0127146, 2015 | 37 | 2015 |
| Risk factors for local recurrence of large, flat colorectal polyps after endoscopic mucosal resection T Zhan, T Hielscher, F Hahn, C Hauf, J Betge, MP Ebert, S Belle Digestion 93 (4), 311-317, 2016 | 33 | 2016 |
| Predicting response to neoadjuvant chemoradiotherapy in rectal cancer: from biomarkers to tumor models M Li, Q Xiao, N Venkatachalam, RD Hofheinz, MR Veldwijk, C Herskind, ... Therapeutic Advances in Medical Oncology 14, 17588359221077972, 2022 | 30 | 2022 |
| The drug-induced phenotypic landscape of colorectal cancer organoids J Betge, N Rindtorff, J Sauer, B Rauscher, C Dingert, H Gaitantzi, ... Nature Communications 13 (1), 3135, 2022 | 26 | 2022 |
| A multicenter open-label phase II trial to evaluate nivolumab and ipilimumab for 2nd line therapy in elderly patients with advanced esophageal squamous cell cancer (RAMONA) NM Meindl-Beinker, J Betge, T Gutting, E Burgermeister, S Belle, T Zhan, ... BMC cancer 19, 1-8, 2019 | 20 | 2019 |
| PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells T Gutting, V Hauber, J Pahl, K Klapproth, W Wu, I Dobrota, F Herweck, ... Oncoimmunology 10 (1), 1906500, 2021 | 19 | 2021 |
| Cross-talk between p53 and Wnt signaling in cancer Q Xiao, J Werner, N Venkatachalam, KE Boonekamp, MP Ebert, T Zhan Biomolecules 12 (3), 453, 2022 | 18 | 2022 |
Michael BoutrosGerman Cancer Research Center (DKFZ) and Heidelberg UniversityVerified email at dkfz.de
