Molecular structure and gas chromatographic retention behavior of the components of ylang‐ylang oil J Olivero, T Gracia, P Payares, R Vivas, D Díaz, E Daza, P Geerlings Journal of pharmaceutical sciences 86 (5), 625-630, 1997 | 71 | 1997 |
Tetraoxane antimalarials and their reaction with Fe (II) I Opsenica, N Terzić, D Opsenica, G Angelovski, M Lehnig, P Eilbracht, ... Journal of medicinal chemistry 49 (13), 3790-3799, 2006 | 70 | 2006 |
Discovery of LX2761, a sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor restricted to the intestinal lumen, for the treatment of diabetes NC Goodwin, ZM Ding, BA Harrison, ED Strobel, AL Harris, M Smith, ... Journal of Medicinal Chemistry 60 (2), 710-721, 2017 | 60 | 2017 |
Prediction of the gas chromatographic relative retention times of flavonoids from molecular structure P Payares, D Díaz, J Olivero, R Vivas, I Gómez Journal of Chromatography A 771 (1-2), 213-219, 1997 | 44 | 1997 |
In vitro and in vivo efficacy and in vitro metabolism of 1-phenyl-3-aryl-2-propen-1-ones against Plasmodium falciparum CE Gutteridge, DA Nichols, SM Curtis, DS Thota, JV Vo, L Gerena, ... Bioorganic & medicinal chemistry letters 16 (21), 5682-5686, 2006 | 37 | 2006 |
Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys C Fischer, SL Zultanski, H Zhou, JL Methot, S Shah, I Hayashi, BL Hughes, ... Bioorganic & Medicinal Chemistry Letters 25 (17), 3488-3494, 2015 | 33 | 2015 |
In vitro metabolism of phenoxypropoxybiguanide analogues in human liver microsomes to potent antimalarial dihydrotriazines TW Shearer, MP Kozar, MT O'Neil, PL Smith, GA Schiehser, DP Jacobus, ... Journal of medicinal chemistry 48 (8), 2805-2813, 2005 | 29 | 2005 |
Triazoles as γ-secretase modulators C Fischer, SL Zultanski, H Zhou, JL Methot, WC Brown, DM Mampreian, ... Bioorganic & medicinal chemistry letters 21 (13), 4083-4087, 2011 | 25 | 2011 |
The role of in vitro ADME assays in antimalarial drug discovery and development TW Shearer, KS Smith, D Diaz, C Asher, J Ramirez Combinatorial Chemistry & High Throughput Screening 8 (1), 89-98, 2005 | 18 | 2005 |
Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate—JPC2056—in cynomolgus monkeys using an in vivo–in vitro model MD Edstein, BM Kotecka, AL Ager, KS Smith, CA DiTusa, DS Diaz, ... Journal of antimicrobial chemotherapy 60 (4), 811-818, 2007 | 17 | 2007 |
Role of specific cytochrome P450 isoforms in the conversion of phenoxypropoxybiguanide analogs in human liver microsomes to potent antimalarial dihydrotriazines DS Diaz, MP Kozar, KS Smith, CO Asher, JC Sousa, GA Schiehser, ... Drug metabolism and disposition 36 (2), 380-385, 2008 | 16 | 2008 |
LP‐925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT 1 and SGLT 2 DR Powell, MG Smith, DD Doree, AL Harris, WW Xiong, F Mseeh, ... Pharmacology Research & Perspectives 3 (2), e00129, 2015 | 13 | 2015 |
Potent benzoazepinone γ-secretase modulators with improved bioavailability JL Methot, C Fischer, C Li, A Rivkin, SP Ahearn, WC Brown, S Kattar, ... Bioorganic & Medicinal Chemistry Letters 25 (17), 3495-3500, 2015 | 12 | 2015 |
Lead optimization of 4, 4-biaryl piperidine amides as γ-secretase inhibitors J Close, R Heidebrecht Jr, J Hendrix, C Li, B Munoz, L Surdi, S Kattar, ... Bioorganic & medicinal chemistry letters 22 (9), 3203-3207, 2012 | 9 | 2012 |
Flow cytometry evaluation of cell cycle arrest in A549 human non-small cell lung cancer cells and tumors following treatment with cell cycle inhibitors: A multifaceted approach … EE Trachet, E Cluff, AL de Matos, D Diaz, C Holmquist, P Gonzales Cancer Research 84 (6_Supplement), 510-510, 2024 | | 2024 |
Inhibition of HDAC3 induces BRCAness and potent synergy with PARP inhibition in neuroendocrine prostate and small cell lung cancers S Nagl, K Devore, G Hirschfeld, K Kotlarczyk, D Diaz, T Wang, M Murray, ... Cancer Research 82 (12_Supplement), 2607-2607, 2022 | | 2022 |
Intratumorally administrated encapsulated IL-12 (PCX12) promotes anti-tumor immune response in GL-261 murine orthotopic glioma model S Lakshmikanthan, D Diaz, P Kolli, A Thiagalingam, PM Gonzales, ... Cancer Research 82 (12_Supplement), 2086-2086, 2022 | | 2022 |
20P IGN002 (antiCD20-IFNα2b) intravenously administered tumour targeted delivery of IFNα2b and its effects in non-Hodgkin lymphoma S Lakshmikanthan, PS Kolli, M Tugnait, J Dalsing-Hernandez, D Diaz, ... Annals of Oncology 32, S9, 2021 | | 2021 |
DMD# 13920 DS Diaz, MP Kozar, KS Smith, CO Asher, JC Sousa, GA Schiehser, ... | | 2007 |
In vitro metabolism of third generation antifolate antimalarials by human and animal liver microsomes and human cytochrome P450 isoforms TW Shearer, MP Kozar, M O'Neil, KS Smith, V Melendez, S Quartucci, ... DRUG METABOLISM REVIEWS 35, 38-38, 2003 | | 2003 |