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Damaris Diaz
Damaris Diaz
Translational Drug Development - TD2
Dirección de correo verificada de td2inc.com
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Molecular structure and gas chromatographic retention behavior of the components of ylang‐ylang oil
J Olivero, T Gracia, P Payares, R Vivas, D Díaz, E Daza, P Geerlings
Journal of pharmaceutical sciences 86 (5), 625-630, 1997
711997
Tetraoxane antimalarials and their reaction with Fe (II)
I Opsenica, N Terzić, D Opsenica, G Angelovski, M Lehnig, P Eilbracht, ...
Journal of medicinal chemistry 49 (13), 3790-3799, 2006
702006
Discovery of LX2761, a sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor restricted to the intestinal lumen, for the treatment of diabetes
NC Goodwin, ZM Ding, BA Harrison, ED Strobel, AL Harris, M Smith, ...
Journal of Medicinal Chemistry 60 (2), 710-721, 2017
602017
Prediction of the gas chromatographic relative retention times of flavonoids from molecular structure
P Payares, D Díaz, J Olivero, R Vivas, I Gómez
Journal of Chromatography A 771 (1-2), 213-219, 1997
441997
In vitro and in vivo efficacy and in vitro metabolism of 1-phenyl-3-aryl-2-propen-1-ones against Plasmodium falciparum
CE Gutteridge, DA Nichols, SM Curtis, DS Thota, JV Vo, L Gerena, ...
Bioorganic & medicinal chemistry letters 16 (21), 5682-5686, 2006
372006
Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys
C Fischer, SL Zultanski, H Zhou, JL Methot, S Shah, I Hayashi, BL Hughes, ...
Bioorganic & Medicinal Chemistry Letters 25 (17), 3488-3494, 2015
332015
In vitro metabolism of phenoxypropoxybiguanide analogues in human liver microsomes to potent antimalarial dihydrotriazines
TW Shearer, MP Kozar, MT O'Neil, PL Smith, GA Schiehser, DP Jacobus, ...
Journal of medicinal chemistry 48 (8), 2805-2813, 2005
292005
Triazoles as γ-secretase modulators
C Fischer, SL Zultanski, H Zhou, JL Methot, WC Brown, DM Mampreian, ...
Bioorganic & medicinal chemistry letters 21 (13), 4083-4087, 2011
252011
The role of in vitro ADME assays in antimalarial drug discovery and development
TW Shearer, KS Smith, D Diaz, C Asher, J Ramirez
Combinatorial Chemistry & High Throughput Screening 8 (1), 89-98, 2005
182005
Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate—JPC2056—in cynomolgus monkeys using an in vivoin vitro model
MD Edstein, BM Kotecka, AL Ager, KS Smith, CA DiTusa, DS Diaz, ...
Journal of antimicrobial chemotherapy 60 (4), 811-818, 2007
172007
Role of specific cytochrome P450 isoforms in the conversion of phenoxypropoxybiguanide analogs in human liver microsomes to potent antimalarial dihydrotriazines
DS Diaz, MP Kozar, KS Smith, CO Asher, JC Sousa, GA Schiehser, ...
Drug metabolism and disposition 36 (2), 380-385, 2008
162008
LP‐925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT 1 and SGLT 2
DR Powell, MG Smith, DD Doree, AL Harris, WW Xiong, F Mseeh, ...
Pharmacology Research & Perspectives 3 (2), e00129, 2015
132015
Potent benzoazepinone γ-secretase modulators with improved bioavailability
JL Methot, C Fischer, C Li, A Rivkin, SP Ahearn, WC Brown, S Kattar, ...
Bioorganic & Medicinal Chemistry Letters 25 (17), 3495-3500, 2015
122015
Lead optimization of 4, 4-biaryl piperidine amides as γ-secretase inhibitors
J Close, R Heidebrecht Jr, J Hendrix, C Li, B Munoz, L Surdi, S Kattar, ...
Bioorganic & medicinal chemistry letters 22 (9), 3203-3207, 2012
92012
Flow cytometry evaluation of cell cycle arrest in A549 human non-small cell lung cancer cells and tumors following treatment with cell cycle inhibitors: A multifaceted approach …
EE Trachet, E Cluff, AL de Matos, D Diaz, C Holmquist, P Gonzales
Cancer Research 84 (6_Supplement), 510-510, 2024
2024
Inhibition of HDAC3 induces BRCAness and potent synergy with PARP inhibition in neuroendocrine prostate and small cell lung cancers
S Nagl, K Devore, G Hirschfeld, K Kotlarczyk, D Diaz, T Wang, M Murray, ...
Cancer Research 82 (12_Supplement), 2607-2607, 2022
2022
Intratumorally administrated encapsulated IL-12 (PCX12) promotes anti-tumor immune response in GL-261 murine orthotopic glioma model
S Lakshmikanthan, D Diaz, P Kolli, A Thiagalingam, PM Gonzales, ...
Cancer Research 82 (12_Supplement), 2086-2086, 2022
2022
20P IGN002 (antiCD20-IFNα2b) intravenously administered tumour targeted delivery of IFNα2b and its effects in non-Hodgkin lymphoma
S Lakshmikanthan, PS Kolli, M Tugnait, J Dalsing-Hernandez, D Diaz, ...
Annals of Oncology 32, S9, 2021
2021
DMD# 13920
DS Diaz, MP Kozar, KS Smith, CO Asher, JC Sousa, GA Schiehser, ...
2007
In vitro metabolism of third generation antifolate antimalarials by human and animal liver microsomes and human cytochrome P450 isoforms
TW Shearer, MP Kozar, M O'Neil, KS Smith, V Melendez, S Quartucci, ...
DRUG METABOLISM REVIEWS 35, 38-38, 2003
2003
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