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Laia Guardia-Escote
Laia Guardia-Escote
Lecturer in Toxicology - Department of Pharmacology, Toxicology and Therapeutic Chemistry, UB
Dirección de correo verificada de ub.edu
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Long-term effects of low doses of Chlorpyrifos exposure at the preweaning developmental stage: A locomotor, pharmacological, brain gene expression and gut microbiome analysis
C Perez-Fernandez, M Morales-Navas, L Guardia-Escote, ...
Food and chemical toxicology 135, 110865, 2020
442020
Medium and long-term effects of low doses of Chlorpyrifos during the postnatal, preweaning developmental stage on sociability, dominance, gut microbiota and plasma metabolites
C Perez-Fernandez, M Morales-Navas, LM Aguilera-Sáez, AC Abreu, ...
Environmental Research 184, 109341, 2020
382020
Obesogenic effects of chlorpyrifos and its metabolites during the differentiation of 3T3-L1 preadipocytes
J Blanco, L Guardia-Escote, M Mulero, P Basaure, J Biosca-Brull, ...
Food and chemical toxicology 137, 111171, 2020
282020
APOE genotype and postnatal chlorpyrifos exposure modulate gut microbiota and cerebral short-chain fatty acids in preweaning mice
L Guardia-Escote, P Basaure, J Biosca-Brull, M Cabré, J Blanco, ...
Food and chemical toxicology 135, 110872, 2020
272020
Learning, memory and the expression of cholinergic components in mice are modulated by the pesticide chlorpyrifos depending upon age at exposure and apolipoprotein E (APOE …
P Basaure, L Guardia-Escote, M Cabré, F Peris-Sampedro, ...
Archives of Toxicology 93, 693-707, 2019
222019
Postnatal exposure to chlorpyrifos produces long-term effects on spatial memory and the cholinergic system in mice in a sex-and APOE genotype-dependent manner
L Guardia-Escote, P Basaure, J Blanco, M Cabré, C Pérez-Fernández, ...
Food and chemical toxicology 122, 1-10, 2018
222018
Postnatal chlorpyrifos exposure and apolipoprotein E (APOE) genotype differentially affect cholinergic expression and developmental parameters in transgenic mice
P Basaure, L Guardia-Escote, M Cabré, F Peris-Sampedro, ...
Food and chemical toxicology 118, 42-52, 2018
212018
Postnatal exposure to low doses of Chlorpyrifos induces long-term effects on 5C-SRTT learning and performance, cholinergic and GABAergic systems and BDNF expression
C Perez-Fernandez, M Morales-Navas, L Guardia-Escote, MT Colomina, ...
Experimental Neurology 330, 113356, 2020
172020
New mechanistic insights on the metabolic-disruptor role of chlorpyrifos in apoE mice: A focus on insulin-and leptin-signalling pathways
F Peris-Sampedro, J Blanco, M Cabré, P Basaure, L Guardia-Escote, ...
Archives of Toxicology 92, 1717-1728, 2018
152018
Exposure to chlorpyrifos at different ages triggers APOE genotype-specific responses in social behavior, body weight and hypothalamic gene expression
P Basaure, L Guardia-Escote, J Biosca-Brull, J Blanco, M Cabré, ...
Environmental research 178, 108684, 2019
122019
Sex and Exposure to Postnatal Chlorpyrifos Influence the Epigenetics of Feeding-Related Genes in a Transgenic APOE Mouse Model: Long-Term Implications on …
L Guardia-Escote, J Blanco, P Basaure, J Biosca-Brull, ...
International Journal of Environmental Research and Public Health 18 (1), 184, 2021
92021
Prenatal, but not postnatal exposure to chlorpyrifos affects social behavior of mice and the excitatory-inhibitory balance in a sex-dependent manner
J Biosca-Brull, L Guardia-Escote, J Blanco, P Basaure, M Cabré, ...
Food and Chemical Toxicology 169, 113423, 2022
62022
Influence of gestational chlorpyrifos exposure on ASD-like behaviors in an fmr1-KO rat model
C Perez-Fernandez, M Matamala Montoya, M Morales-Navas, ...
Molecular Neurobiology 59 (9), 5835-5855, 2022
62022
Exposure to chlorpyrifos during pregnancy differentially affects social behavior and GABA signaling elements in an APOE-and sex-dependent manner in a transgenic mouse model
J Biosca-Brull, L Guardia-Escote, P Basaure, M Cabré, J Blanco, ...
Environmental Research 224, 115461, 2023
52023
APOE genetic background and sex confer different vulnerabilities to postnatal chlorpyrifos exposure and modulate the response to cholinergic drugs
L Guardia-Escote, P Basaure, F Peris-Sampedro, J Biosca-Brull, M Cabré, ...
Behavioural Brain Research 376, 112195, 2019
52019
Protocols for the Evaluation of Neurodevelopmental Alterations in Rabbit Models In Vitro and In Vivo
L Pla, BA Kühne, L Guardia-Escote, P Vázquez-Aristizabal, C Loreiro, ...
Frontiers in Toxicology 4, 918520, 2022
42022
Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice
L Guardia-Escote, J Biosca-Brull, M Cabré, J Blanco, ...
Archives of Toxicology 97 (9), 2463-2475, 2023
22023
Pesticides and aging: Preweaning exposure to Chlorpyrifos induces a general hypomotricity state in late-adult rats
C Perez-Fernandez, M Morales-Navas, L Guardia-Escote, MT Colomina, ...
Neurotoxicology 86, 69-77, 2021
22021
Improvement of APOE4-dependent non-cognitive behavioural traits by postnatal cholinergic stimulation in female mice
F Peris-Sampedro, L Guardia-Escote, P Basaure, M Cabré, MT Colomina
Behavioural Brain Research 384, 112552, 2020
22020
Behavioral endpoints in adult and developmental neurotoxicity: the case of organophosphate pesticides
L Guardia-Escote, J Biosca-Brull, M Morales, C Perez-Fernandez, ...
Toxicological Risk Assessment and Multi-System Health Impacts from Exposure …, 2021
12021
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