Bryan D. Choi, M.D., Ph.D.
Bryan D. Choi, M.D., Ph.D.
Massachusetts General Hospital
Verified email at
Cited by
Cited by
EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss
JH Sampson, BD Choi, L Sanchez-Perez, CM Suryadevara, DJ Snyder, ...
Clinical Cancer Research 20 (4), 972-984, 2014
Egfrviii‐targeted vaccination therapy of malignant glioma
BD Choi, GE Archer, DA Mitchell, AB Heimberger, RE McLendon, ...
Brain pathology 19 (4), 713-723, 2009
Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma
BD Choi, CT Kuan, M Cai, GE Archer, DA Mitchell, PC Gedeon, ...
Proceedings of the National Academy of Sciences 110 (1), 270-275, 2013
EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma
H Miao, BD Choi, CM Suryadevara, L Sanchez-Perez, S Yang, G De Leon, ...
PloS one 9 (4), e94281, 2014
Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma
BD Choi, CM Suryadevara, PC Gedeon, JE Herndon II, L Sanchez-Perez, ...
Journal of clinical neuroscience 21 (1), 189-190, 2014
Bispecific antibodies engage T cells for antitumor immunotherapy
BD Choi, M Cai, DD Bigner, AI Mehta, CT Kuan, JH Sampson
Expert opinion on biological therapy 11 (7), 843-853, 2011
CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity
BD Choi, X Yu, AP Castano, AA Bouffard, A Schmidts, RC Larson, ...
Nature biotechnology 37 (9), 1049-1058, 2019
Myeloablative temozolomide enhances CD8+ T-cell responses to vaccine and is required for efficacy against brain tumors in mice
LA Sanchez-Perez, BD Choi, GE Archer, X Cui, C Flores, LA Johnson, ...
PloS one 8 (3), e59082, 2013
Tisagenlecleucel CAR T-cell therapy in secondary CNS lymphoma
MJ Frigault, J Dietrich, M Martinez-Lage, M Leick, BD Choi, Z DeFilipp, ...
Blood 134 (11), 860-866, 2019
Factors influencing fellowship selection, career trajectory, and academic productivity among plastic surgeons
MR DeLong, DB Hughes, VJ Tandon, BD Choi, MR Zenn
Plastic and reconstructive surgery 133 (3), 730-736, 2014
Are BiTEs the “missing link” in cancer therapy?
CM Suryadevara, PC Gedeon, L Sanchez-Perez, T Verla, ...
Oncoimmunology 4 (6), e1008339, 2015
Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody
BD Choi, PC Gedeon, JE Herndon, GE Archer, EA Reap, ...
Cancer immunology research 1 (3), 163-167, 2013
Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma
CM Suryadevara, R Desai, ML Abel, KA Riccione, KA Batich, SH Shen, ...
Oncoimmunology 7 (6), e1434464, 2018
Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody
BD Choi, PC Gedeon, L Sanchez-Perez, DD Bigner, JH Sampson
Oncoimmunology 2 (12), e26757, 2013
CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma
BD Choi, X Yu, AP Castano, H Darr, DB Henderson, AA Bouffard, ...
Journal for immunotherapy of cancer 7 (1), 1-8, 2019
Chimeric antigen receptor costimulation domains modulate human regulatory T cell function
AC Boroughs, RC Larson, BD Choi, AA Bouffard, LS Riley, E Schiferle, ...
JCI insight 4 (8), 2019
Immunotherapy for malignant glioma
CM Suryadevara, T Verla, L Sanchez-Perez, EA Reap, BD Choi, PE Fecci, ...
Surgical neurology international 6 (Suppl 1), S68, 2015
Convection enhanced delivery of macromolecules for brain tumors
A I Mehta, B D Choi, D Ajay, R Raghavan, M Brady, A H Friedman, ...
Current Drug Discovery Technologies 9 (4), 305-310, 2012
Isocitrate dehydrogenase 1: what it means to the neurosurgeon: a review
TR Hodges, BD Choi, DD Bigner, H Yan, JH Sampson
Journal of neurosurgery 118 (6), 1176-1180, 2013
Impact of PhD training on scholarship in a neurosurgical career
BD Choi, MR DeLong, DM DeLong, AH Friedman, JH Sampson
Journal of Neurosurgery 120 (3), 730-735, 2014
The system can't perform the operation now. Try again later.
Articles 1–20