Bryan D. Choi, M.D., Ph.D.
Bryan D. Choi, M.D., Ph.D.
Massachusetts General Hospital
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EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss
JH Sampson, BD Choi, L Sanchez-Perez, CM Suryadevara, DJ Snyder, ...
Clinical Cancer Research 20 (4), 972-984, 2014
EGFRvIII‐targeted vaccination therapy of malignant glioma
BD Choi, GE Archer, DA Mitchell, AB Heimberger, RE McLendon, ...
Brain pathology 19 (4), 713-723, 2009
Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma
BD Choi, CT Kuan, M Cai, GE Archer, DA Mitchell, PC Gedeon, ...
Proceedings of the National Academy of Sciences 110 (1), 270-275, 2013
EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma
H Miao, BD Choi, CM Suryadevara, L Sanchez-Perez, S Yang, G De Leon, ...
PloS one 9 (4), e94281, 2014
Bispecific antibodies engage T cells for antitumor immunotherapy
BD Choi, M Cai, DD Bigner, AI Mehta, CT Kuan, JH Sampson
Expert opinion on biological therapy 11 (7), 843-853, 2011
Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma
BD Choi, CM Suryadevara, PC Gedeon, JE Herndon II, L Sanchez-Perez, ...
Journal of Clinical Neuroscience 21 (1), 189-190, 2014
Myeloablative temozolomide enhances CD8+ T-cell responses to vaccine and is required for efficacy against brain tumors in mice
LA Sanchez-Perez, BD Choi, GE Archer, X Cui, C Flores, LA Johnson, ...
PloS one 8 (3), e59082, 2013
Factors influencing fellowship selection, career trajectory, and academic productivity among plastic surgeons
MR DeLong, DB Hughes, VJ Tandon, BD Choi, MR Zenn
Plastic and reconstructive surgery 133 (3), 730-736, 2014
Are BiTEs the “missing link” in cancer therapy?
CM Suryadevara, PC Gedeon, L Sanchez-Perez, T Verla, ...
Oncoimmunology 4 (6), e1008339, 2015
Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody
BD Choi, PC Gedeon, JE Herndon, GE Archer, EA Reap, ...
Cancer immunology research 1 (3), 163-167, 2013
Immunotherapy for malignant glioma
CM Suryadevara, T Verla, L Sanchez-Perez, EA Reap, BD Choi, PE Fecci, ...
Surgical neurology international 6 (Suppl 1), S68, 2015
Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody
BD Choi, PC Gedeon, L Sanchez-Perez, DD Bigner, JH Sampson
Oncoimmunology 2 (12), e26757, 2013
Isocitrate dehydrogenase 1: what it means to the neurosurgeon: a review
TR Hodges, BD Choi, DD Bigner, H Yan, JH Sampson
Journal of neurosurgery 118 (6), 1176-1180, 2013
A novel bispecific antibody recruits T cells to eradicate tumors in the “immunologically privileged” central nervous system
BD Choi, I Pastan, DD Bigner, JH Sampson
Oncoimmunology 2 (4), e23639, 2013
Convection enhanced delivery of macromolecules for brain tumors
A I Mehta, B D Choi, D Ajay, R Raghavan, M Brady, A H Friedman, ...
Current drug discovery technologies 9 (4), 305-310, 2012
Imaging of convection enhanced delivery of toxins in humans
AI Mehta, BD Choi, R Raghavan, M Brady, AH Friedman, DD Bigner, ...
Toxins 3 (3), 201-206, 2011
Enzyme redesign guided by cancer-derived IDH1 mutations
ZJ Reitman, BD Choi, I Spasojevic, DD Bigner, JH Sampson, H Yan
Nature chemical biology 8 (11), 887, 2012
Impact of PhD training on scholarship in a neurosurgical career
BD Choi, MR DeLong, DM DeLong, AH Friedman, JH Sampson
Journal of neurosurgery 120 (3), 730-735, 2014
Rindopepimut: anti-EGFRvIII peptide vaccine, oncolytic
PC Gedeon, BD Choi, JH Sampson, DD Bigner
Drugs of the Future 38 (3), 147, 2013
An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma
PC Gedeon, BD Choi, TR Hodges, DA Mitchell, DD Bigner, JH Sampson
Expert review of clinical pharmacology 6 (4), 375-386, 2013
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Artículos 1–20