Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers S Yip, YS Butterfield, O Morozova, S Chittaranjan, MD Blough, J An, I Birol, ... The Journal of pathology 226 (1), 7-16, 2012 | 337 | 2012 |
Lactate dehydrogenase A silencing in IDH mutant gliomas C Chesnelong, MM Chaumeil, MD Blough, M Al-Najjar, OD Stechishin, ... Neuro-oncology 16 (5), 686-695, 2014 | 191 | 2014 |
An in vivo patient-derived model of endogenous IDH1-mutant glioma HA Luchman, OD Stechishin, NH Dang, MD Blough, C Chesnelong, ... Neuro-oncology 14 (2), 184-191, 2011 | 191 | 2011 |
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism JL Izquierdo-Garcia, P Viswanath, P Eriksson, L Cai, M Radoul, ... Cancer research 75 (15), 2999-3009, 2015 | 134 | 2015 |
Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression A De Boeck, BY Ahn, C D’Mello, X Lun, SV Menon, MM Alshehri, ... Nature communications 11 (1), 4997, 2020 | 124 | 2020 |
On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells OD Stechishin, HA Luchman, Y Ruan, MD Blough, SA Nguyen, JJ Kelly, ... Neuro-oncology 15 (2), 198-207, 2013 | 122 | 2013 |
Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma MD Blough, DC Beauchamp, MR Westgate, JJ Kelly, JG Cairncross Journal of neuro-oncology 102, 1-7, 2011 | 114 | 2011 |
O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells MD Blough, MC Zlatescu, JG Cairncross Cancer research 67 (2), 580-584, 2007 | 109 | 2007 |
Oligodendroglioma cell lines containing t (1; 19)(q10; p10) JJP Kelly, MD Blough, ODM Stechishin, JAW Chan, D Beauchamp, ... Neuro-oncology 12 (7), 745-755, 2010 | 99 | 2010 |
p53 Binding to the p21 promoter is dependent on the nature of DNA damage E Bodzak, MD Blough, PWK Lee, R Hill Cell Cycle 7 (16), 2535-2543, 2008 | 85 | 2008 |
Sensitivity to temozolomide in brain tumor initiating cells MD Blough, MR Westgate, D Beauchamp, JJ Kelly, O Stechishin, ... Neuro-oncology 12 (7), 756-760, 2010 | 82 | 2010 |
A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes T Spence, C Perotti, P Sin-Chan, D Picard, W Wu, A Singh, C Anderson, ... Neuro-oncology 16 (1), 62-71, 2014 | 75 | 2014 |
Hyperpolarized 13C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring MM Chaumeil, M Radoul, C Najac, P Eriksson, P Viswanath, MD Blough, ... NeuroImage: Clinical 12, 180-189, 2016 | 67 | 2016 |
Single-cell landscapes of primary glioblastomas and matched explants and cell lines show variable retention of inter-and intratumor heterogeneity VG LeBlanc, DL Trinh, S Aslanpour, M Hughes, D Livingstone, D Jin, ... Cancer Cell 40 (4), 379-392. e9, 2022 | 61 | 2022 |
Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells N Grinshtein, CC Rioseco, R Marcellus, D Uehling, A Aman, X Lun, ... Oncotarget 7 (37), 59360, 2016 | 49 | 2016 |
Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors B Davis, Terry Fox Research Institute Glioblastoma Consortium, Y Shen, ... Neuro-oncology 18 (3), 350-360, 2015 | 48 | 2015 |
Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity S Chittaranjan, S Chan, C Yang, KC Yang, V Chen, A Moradian, M Firme, ... Oncotarget 5 (17), 7960, 2014 | 47 | 2014 |
Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments Y Shen, CJ Grisdale, SA Islam, P Bose, J Lever, EY Zhao, N Grinshtein, ... Proceedings of the National Academy of Sciences 116 (38), 19098-19108, 2019 | 46 | 2019 |
Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors ST Ahmad, AD Rogers, MJ Chen, R Dixit, L Adnani, LS Frankiw, SO Lawn, ... Nature communications 10 (1), 2000, 2019 | 43 | 2019 |
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts AL Yuan, CB Ricks, AK Bohm, X Lun, L Maxwell, S Safdar, S Bukhari, ... PLoS One 13 (8), e0202860, 2018 | 30 | 2018 |