| Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling MJ Acuña, P Pessina, H Olguin, D Cabrera, CP Vio, M Bader, ... Human molecular genetics 23 (5), 1237-1249, 2014 | 178 | 2014 |
| Angiotensin II-induced pro-fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells MG Morales, Y Vazquez, MJ Acuña, JC Rivera, F Simon, JD Salas, JÁ Ruf, ... The international journal of biochemistry & cell biology 44 (11), 1993-2002, 2012 | 101 | 2012 |
| The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates transforming growth factor (TGF)-β-dependent … C Cabello-Verrugio, C Santander, C Cofré, MJ Acuña, F Melo, E Brandan Journal of Biological Chemistry 287 (9), 6773-6787, 2012 | 86 | 2012 |
| Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas MG Morales, J Abrigo, MJ Acuña, RA Santos, M Bader, E Brandan, ... Disease models & mechanisms 9 (4), 441-449, 2016 | 84 | 2016 |
| Fibrotic response induced by angiotensin-II requires NAD (P) H oxidase-induced reactive oxygen species (ROS) in skeletal muscle cells C Cabello-Verrugio, MJ Acuña, MG Morales, A Becerra, F Simon, ... Biochemical and Biophysical Research Communications 410 (3), 665-670, 2011 | 78 | 2011 |
| ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis C Riquelme, MJ Acuña, J Torrejón, D Rebolledo, D Cabrera, RA Santos, ... PloS one 9 (4), e93449, 2014 | 69 | 2014 |
| The anti-adipogenic effect of angiotensin II on human preadipose cells involves ERK1, 2 activation and PPARγ phosphorylation P Fuentes, MJ Acuña, M Cifuentes, CV Rojas J Endocrinol 206, 75-83, 2010 | 62 | 2010 |
| HIF-hypoxia signaling in skeletal muscle physiology and fibrosis R Valle-Tenney, D Rebolledo, MJ Acuña, E Brandan Journal of cell communication and signaling 14 (2), 147-158, 2020 | 55 | 2020 |
| The pro-fibrotic connective tissue growth factor (CTGF/CCN2) correlates with the number of necrotic-regenerative foci in dystrophic muscle MG Morales, MJ Acuña, D Cabrera, R Goldschmeding, E Brandan Journal of Cell Communication and Signaling 12, 413-421, 2018 | 52 | 2018 |
| Larger anti‐adipogenic effect of angiotensin II on omental preadipose cells of obese humans R Brücher, M Cifuentes, MJ Acuña, C Albala, CV Rojas Obesity 15 (7), 1643-1646, 2007 | 44 | 2007 |
| Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD‐and p38 MAPK‐dependent mechanism in skeletal muscle P Painemal, MJ Acuña, C Riquelme, E Brandan, C Cabello‐Verrugio Biofactors 39 (4), 467-475, 2013 | 40 | 2013 |
| The functional and molecular effects of problematic alcohol consumption on skeletal muscle: a focus on athletic performance C Caceres-Ayala, RM Pautassi, MJ Acuña, W Cerpa, DL Rebolledo The American journal of drug and alcohol abuse 48 (2), 133-147, 2022 | 23 | 2022 |
| Blockade of Bradykinin receptors worsens the dystrophic phenotype of mdx mice: differential effects for B1 and B2 receptors MJ Acuña, D Salas, A Córdova-Casanova, M Cruz-Soca, C Céspedes, ... Journal of Cell Communication and Signaling 12, 589-601, 2018 | 21 | 2018 |
| Role of matricellular CCN proteins in skeletal muscle: focus on CCN2/CTGF and its regulation by vasoactive peptides DL Rebolledo, MJ Acuña, E Brandan International Journal of Molecular Sciences 22 (10), 5234, 2021 | 15 | 2021 |
| Proliferation and differentiation of human adipocyte precursor cells: differences between the preperitoneal and subcutaneous compartments M Fernández, MJ Acuna, M Reyes, D Olivares, S Hirsch, D Bunout, ... Journal of cellular biochemistry 111 (3), 659-664, 2010 | 15 | 2010 |
| Transforming growth factor type‐β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular … C Cofre, MJ Acuña, O Contreras, MG Morales, C Riquelme, ... Biofactors 41 (2), 111-120, 2015 | 11 | 2015 |
| Episodic binge-like ethanol reduces skeletal muscle strength associated with atrophy, fibrosis, and inflammation in young rats C Cáceres-Ayala, RG Mira, MJ Acuña, E Brandan, W Cerpa, ... International Journal of Molecular Sciences 24 (2), 1655, 2023 | 8 | 2023 |
| Analysis of pathological activities of CCN2/CTGF in muscle dystrophy MJ Acuña, E Brandan CCN Proteins: Methods and Protocols, 513-521, 2017 | 5 | 2017 |
| Skeletal muscle system MJ Acuña, E Brandan, D Motta-Santos Angiotensin-(1-7) A Comprehensive Review, 169-190, 2019 | 3 | 2019 |
| The internal region leucine-rich repeat 6 of decorin interacts with LRP-1, modulates TGF-β dependent signaling and inhibits TGF-β dependent fibrotic response in skeletal muscles C Cabello-Verrugio, C Santander, C Jofre, MJ Acuna, F Melo, E Brandan J Biol Chem, 2011 | 2 | 2011 |
Enrique Brandan, Ph.D.Fundación Ciencia & Vida, Full Professor, Facultad de Medicina y Ciencia Universidad San SebastiánDirección de correo verificada de cienciavida.org
