| Clinical and toxicological relevance of CYP2C9: drug-drug interactions and pharmacogenetics AE Rettie, JP Jones Annu. Rev. Pharmacol. Toxicol. 45, 477-494, 2005 | 343 | 2005 |
| Pharmacophore and three-dimensional quantitative structure activity relationship methods for modeling cytochrome p450 active sites S Ekins, MJ de Groot, JP Jones Drug metabolism and disposition 29 (7), 936-944, 2001 | 319 | 2001 |
| Mechanism of oxidative amine dealkylation of substituted N, N-dimethylanilines by cytochrome P-450: application of isotope effect profiles SB Karki, JP Dinnocenzo, JP Jones, KR Korzekwa Journal of the American Chemical Society 117 (13), 3657-3664, 1995 | 178 | 1995 |
| Theoretical studies on cytochrome P-450 mediated hydroxylation: a predictive model for hydrogen atom abstractions KR Korzekwa, JP Jones, JR Gillette Journal of the American Chemical Society 112 (19), 7042-7046, 1990 | 170 | 1990 |
| Alternative splicing determines the function of CYP4F3 by switching substrate specificity P Christmas, JP Jones, CJ Patten, DA Rock, Y Zheng, SM Cheng, ... Journal of Biological Chemistry 276 (41), 38166-38172, 2001 | 164 | 2001 |
| Predicting the cytochrome P450 mediated metabolism of xenobiotics KR Korzekwa, JP Jones Pharmacogenetics and Genomics 3 (1), 1-18, 1993 | 163 | 1993 |
| Computational models for cytochrome P450: a predictive electronic model for aromatic oxidation and hydrogen atom abstraction JP Jones, M Mysinger, KR Korzekwa Drug Metabolism and Disposition 30 (1), 7-12, 2002 | 159 | 2002 |
| A new mechanistic probe for cytochrome P450: an application of isotope effect profiles JI Manchester, JP Dinnocenzo, Higgins, JP Jones Journal of the American Chemical Society 119 (21), 5069-5070, 1997 | 154 | 1997 |
| Isotopically sensitive branching and its effect on the observed intramolecular isotope effects in cytochrome P-450 catalyzed reactions: a new method for the estimation of … JP Jones, KR Korzekwa, AE Rettie, WF Trager Journal of the American Chemical Society 108 (22), 7074-7078, 1986 | 151 | 1986 |
| Three-dimensional quantitative structure-activity relationship for inhibitors of cytochrome P4502C9. JP Jones, M He, WF Trager, AE Rettie Drug Metabolism and Disposition 24 (1), 1-6, 1996 | 147 | 1996 |
| A refined 3-dimensional QSAR of cytochrome P450 2C9: computational predictions of drug interactions S Rao, R Aoyama, M Schrag, WF Trager, A Rettie, JP Jones Journal of medicinal chemistry 43 (15), 2789-2796, 2000 | 137 | 2000 |
| Flavone antagonists bind competitively with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to the aryl hydrocarbon receptor but inhibit nuclear uptake and transformation EC Henry, AS Kende, G Rucci, MJ Totleben, JJ Willey, SD Dertinger, ... Molecular pharmacology 55 (4), 716-725, 1999 | 136 | 1999 |
| The domain structure and retrotransposition mechanism of R2 elements are conserved throughout arthropods. WD Burke, HS Malik, JP Jones, TH Eickbush Molecular biology and evolution 16 (4), 502-511, 1999 | 127 | 1999 |
| Enzymatic determinants of the substrate specificity of CYP2C9: role of B ‘− C loop residues in providing the π-stacking anchor site for warfarin binding RL Haining, JP Jones, KR Henne, MB Fisher, DR Koop, WF Trager, ... Biochemistry 38 (11), 3285-3292, 1999 | 124 | 1999 |
| On isotope effects for the cytochrome P-450 oxidation of substituted N, N-dimethylanilines JP Dinnocenzo, SB Karki, JP Jones Journal of the American Chemical Society 115 (16), 7111-7116, 1993 | 124 | 1993 |
| Electron spin resonance studies of doped synthetic kaolinite. I BR Angel, JPE Jones, PL Hall Clay Minerals 10 (4), 247-255, 1974 | 123 | 1974 |
| Structural forms of phenprocoumon and warfarin that are metabolized at the active site of CYP2C9 M He, KR Korzekwa, JP Jones, AE Rettie, WF Trager Archives of biochemistry and biophysics 372 (1), 16-28, 1999 | 121 | 1999 |
| Evidence for two different active oxygen species in cytochrome P450 BM3 mediated sulfoxidation and N-dealkylation reactions TJ Volz, DA Rock, JP Jones Journal of the American Chemical Society 124 (33), 9724-9725, 2002 | 119 | 2002 |
| The impact of single nucleotide polymorphisms on human aldehyde oxidase T Hartmann, M Terao, E Garattini, C Teutloff, JF Alfaro, JP Jones, ... Drug metabolism and disposition 40 (5), 856-864, 2012 | 111 | 2012 |
| Mechanisms of N-demethylations catalyzed by high-valent species of heme enzymes: novel use of isotope effects and direct observation of intermediates Y Goto, Y Watanabe, S Fukuzumi, JP Jones, JP Dinnocenzo Journal of the American Chemical Society 120 (41), 10762-10763, 1998 | 102 | 1998 |
