HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types A Zirkel, M Nikolic, K Sofiadis, JP Mallm, CA Brackley, H Gothe, ... Molecular cell 70 (4), 730-744. e6, 2018 | 184 | 2018 |
Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19 SJ Theobald, A Simonis, T Georgomanolis, C Kreer, M Zehner, HS Eisfeld, ... EMBO Molecular Medicine 13 (8), e14150, 2021 | 116 | 2021 |
Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1 V Kohlhaas, SJ Blakemore, M Al-Maarri, N Nickel, M Pal, A Roth, ... Blood, The Journal of the American Society of Hematology 137 (5), 646-660, 2021 | 74 | 2021 |
Exploiting native forces to capture chromosome conformation in mammalian cell nuclei L Brant, T Georgomanolis, M Nikolic, CA Brackley, P Kolovos, ... Molecular Systems Biology 12 (12), 891, 2016 | 56 | 2016 |
yylncT defines a class of divergently transcribed lncRNAs and safeguards the T-mediated mesodermal commitment of human PSCs S Frank, G Ahuja, D Bartsch, N Russ, W Yao, JCC Kuo, JP Derks, ... Cell stem cell 24 (2), 318-327. e8, 2019 | 55 | 2019 |
TNF-α-producing macrophages determine subtype identity and prognosis via AP1 enhancer reprogramming in pancreatic cancer M Tu, L Klein, E Espinet, T Georgomanolis, F Wegwitz, X Li, L Urbach, ... Nature cancer 2 (11), 1185-1203, 2021 | 54 | 2021 |
HMGB1 coordinates SASP‐related chromatin folding and RNA homeostasis on the path to senescence K Sofiadis, N Josipovic, M Nikolic, Y Kargapolova, N Übelmesser, ... Molecular systems biology 17 (6), e9760, 2021 | 53 | 2021 |
TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning S Diermeier, P Kolovos, L Heizinger, U Schwartz, T Georgomanolis, ... Genome biology 15, 1-13, 2014 | 53 | 2014 |
Splicing of many human genes involves sites embedded within introns S Kelly, T Georgomanolis, A Zirkel, S Diermeier, D O'Reilly, S Murphy, ... Nucleic acids research 43 (9), 4721-4732, 2015 | 51 | 2015 |
Binding of nuclear factor κB to noncanonical consensus sites reveals its multimodal role during the early inflammatory response P Kolovos, T Georgomanolis, A Koeferle, JD Larkin, L Brant, M Nikolicć, ... Genome Research 26 (11), 1478-1489, 2016 | 49 | 2016 |
DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift J Franzen, T Georgomanolis, A Selich, CC Kuo, R Stöger, L Brant, ... Communications biology 4 (1), 598, 2021 | 38 | 2021 |
Cutting a long intron short: Recursive splicing and its implications T Georgomanolis, K Sofiadis, A Papantonis Frontiers in physiology 7, 598, 2016 | 32 | 2016 |
GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73 ME Lalioti, M Arbi, I Loukas, K Kaplani, A Kalogeropoulou, G Lokka, ... Journal of Cell Science 132 (11), jcs228684, 2019 | 27 | 2019 |
Distinct IL‐1α‐responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner SS Weiterer, J Meier‐Soelch, T Georgomanolis, A Mizi, A Beyerlein, ... The EMBO journal 39 (1), e101533, 2020 | 26 | 2020 |
GemC1 is a critical switch for neural stem cell generation in the postnatal brain ME Lalioti, K Kaplani, G Lokka, T Georgomanolis, C Kyrousi, W Dong, ... Glia 67 (12), 2360-2373, 2019 | 23 | 2019 |
BmCAP, a silkmoth gene encoding multiple protein isoforms characterized by SoHo and SH3 domains: expression analysis during ovarian follicular development T Georgomanolis, K Iatrou, L Swevers Insect biochemistry and molecular biology 39 (12), 892-902, 2009 | 16 | 2009 |
Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life J Selle, K Dinger, V Jentgen, D Zanetti, J Will, T Georgomanolis, C Vohlen, ... Nature Communications 13 (1), 4352, 2022 | 14 | 2022 |
Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies E Izquierdo, D Vorholt, S Blakemore, B Sackey, JL Nolte, V Barbarino, ... Blood, The Journal of the American Society of Hematology 139 (25), 3617-3629, 2022 | 14 | 2022 |
Knoch, TA, van IJcken, WFJ, Cook, PR, Costa, IG, Grosveld, FG & Papantonis, A. Binding of nuclear kappa-B to non-canonical consensus sites reveals its multimodal role during … P Kolovos, T Georgomanolis, A Koeferle, JD Larkin, J Brant, M Nikolić, ... Genome Research 26 (11), 1478-1489, 2016 | 7 | 2016 |
Monoallelic and biallelic variants in LEF1 are associated with a new syndrome combining ectodermal dysplasia and limb malformations caused by altered WNT signaling W Dufour, S Alawbathani, AS Jourdain, M Asif, G Baujat, C Becker, ... Genetics in Medicine 24 (8), 1708-1721, 2022 | 5 | 2022 |