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Piotr Mak
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Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450
IG Denisov, PJ Mak, TM Makris, SG Sligar, JR Kincaid
The Journal of Physical Chemistry A 112 (50), 13172-13179, 2008
1072008
Unveiling the crucial intermediates in androgen production
PJ Mak, MC Gregory, IG Denisov, SG Sligar, JR Kincaid
Proceedings of the National Academy of Sciences 112 (52), 15856-15861, 2015
782015
Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry
M Gregory, PJ Mak, SG Sligar, JR Kincaid
Angewandte Chemie (International ed. in English) 52 (20), 5342, 2013
762013
Spectroscopic studies of the cytochrome P450 reaction mechanisms
PJ Mak, IG Denisov
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (1), 178-204, 2018
712018
Resonance Raman detection of the hydroperoxo intermediate in the cytochrome P450 enzymatic cycle
PJ Mak, IG Denisov, D Victoria, TM Makris, T Deng, SG Sligar, JR Kincaid
Journal of the American Chemical Society 129 (20), 6382-6383, 2007
712007
Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450
PJ Mak, IG Denisov, YV Grinkova, SG Sligar, JR Kincaid
Journal of the American Chemical Society 133 (5), 1357-1366, 2011
622011
Resonance Raman spectroscopy of the oxygenated intermediates of human CYP19A1 implicates a compound I intermediate in the final lyase step
PJ Mak, A Luthra, SG Sligar, JR Kincaid
Journal of the American Chemical Society 136 (13), 4825-4828, 2014
602014
Human cytochrome CYP17A1: The structural basis for compromised lyase activity with 17-hydroxyprogesterone
PJ Mak, R Duggal, IG Denisov, MC Gregory, SG Sligar, JR Kincaid
Journal of the American Chemical Society 140 (23), 7324-7331, 2018
392018
Differential control of heme reactivity in alpha and beta subunits of hemoglobin: A combined Raman spectroscopic and computational study
EM Jones, E Monza, G Balakrishnan, GC Blouin, PJ Mak, Q Zhu, ...
Journal of the American Chemical Society 136 (29), 10325-10339, 2014
382014
Resonance Raman spectroscopy reveals pH-dependent active site structural changes of lactoperoxidase compound 0 and its ferryl heme O–O bond cleavage products
PJ Mak, W Thammawichai, D Wiedenhoeft, JR Kincaid
Journal of the American Chemical Society 137 (1), 349-361, 2015
352015
Experimental documentation of the structural consequences of hydrogen-bonding interactions to the proximal cysteine of a cytochrome P450
PJ Mak, Y Yang, S Im, LA Waskell, JR Kincaid
Angewandte Chemie (International ed. in English) 51 (41), 10403, 2012
342012
Effects of systematic peripheral group deuteration on the low‐frequency resonance Raman spectra of myoglobin derivatives
PJ Mak, E Podstawka, JR Kincaid, LM Proniewicz
Biopolymers: Original Research on Biomolecules 75 (3), 217-228, 2004
332004
The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4
IG Denisov, PJ Mak, YV Grinkova, D Bastien, G Bérubé, SG Sligar, ...
Journal of inorganic biochemistry 158, 77-85, 2016
292016
Defining resonance Raman spectral responses to substrate binding by cytochrome P450 from Pseudomonas putida
PJ Mak, D Kaluka, ME Manyumwa, H Zhang, T Deng, JR Kincaid
Biopolymers: Original Research on Biomolecules 89 (11), 1045-1053, 2008
292008
Resonance Raman studies of cytochrome P450 2B4 in its interactions with substrates and redox partners
PJ Mak, SC Im, H Zhang, LA Waskell, JR Kincaid
Biochemistry 47 (12), 3950-3963, 2008
292008
Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17
PJ Mak, MC Gregory, SG Sligar, JR Kincaid
Biochemistry 53 (1), 90-100, 2014
262014
Resonance Raman spectroscopic studies of hydroperoxo derivatives of cobalt-substituted myoglobin
PJ Mak, JR Kincaid
Journal of inorganic biochemistry 102 (10), 1952-1957, 2008
252008
Probing the structure-function relationship of hemoglobin in living human red blood cells
J Dybas, MJ Bokamper, KM Marzec, PJ Mak
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 239, 118530, 2020
222020
Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives
F Rwere, PJ Mak, JR Kincaid
Biochemistry 47 (48), 12869-12877, 2008
222008
Low frequency resonance Raman spectra of isolated α and β subunits of hemoglobin and their deuterated analogues
E Podstawka, PJ Mak, JR Kincaid, LM Proniewicz
Biopolymers: Original Research on Biomolecules 83 (5), 455-466, 2006
212006
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Articles 1–20