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Heike Wulff
Heike Wulff
Profesor of Pharmacology, University of California, Davis
Dirección de correo verificada de ucdavis.edu
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Voltage-gated potassium channels as therapeutic targets
H Wulff, NA Castle, LA Pardo
Nature reviews Drug discovery 8 (12), 982-1001, 2009
8652009
Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: A potential immunosuppressant
H Wulff, MJ Miller, W Hänsel, S Grissmer, MD Cahalan, KG Chandy
Proceedings of the National Academy of Sciences 97 (14), 8151-8156, 2000
7362000
Ion channels in innate and adaptive immunity
S Feske, H Wulff, EY Skolnik
Annual review of immunology 33, 291-353, 2015
6422015
Kv1. 3 channels are a therapeutic target for T cell-mediated autoimmune diseases
C Beeton, H Wulff, NE Standifer, P Azam, KM Mullen, MW Pennington, ...
Proceedings of the National Academy of Sciences 103 (46), 17414-17419, 2006
6002006
K+ channels as targets for specific immunomodulation
KG Chandy, H Wulff, C Beeton, M Pennington, GA Gutman, MD Cahalan
Trends in pharmacological sciences 25 (5), 280-289, 2004
5522004
The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS
H Wulff, PA Calabresi, R Allie, S Yun, M Pennington, C Beeton, ...
The Journal of clinical investigation 111 (11), 1703-1713, 2003
5452003
International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels
AD Wei, GA Gutman, R Aldrich, KG Chandy, S Grissmer, H Wulff
Pharmacological reviews 57 (4), 463-472, 2005
5002005
Up-regulation of the IKCa1 potassium channel during T-cell activation: molecular mechanism and functional consequences
S Ghanshani, H Wulff, MJ Miller, H Rohm, A Neben, GA Gutman, ...
Journal of Biological Chemistry 275 (47), 37137-37149, 2000
4972000
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels
GA Gutman, KG Chandy, JP Adelman, J Aiyar, DA Bayliss, DE Clapham, ...
Pharmacological reviews 55 (4), 583-586, 2003
4542003
Selective blockade of T lymphocyte K+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis
C Beeton, H Wulff, J Barbaria, O Clot-Faybesse, M Pennington, D Bernard, ...
Proceedings of the national academy of sciences 98 (24), 13942-13947, 2001
4422001
The concise guide to pharmacology 2019/20: Ion channels
SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ...
British journal of pharmacology 176, S142-S228, 2019
3392019
Targeting effector memory T cells with a selective peptide inhibitor of Kv1. 3 channels for therapy of autoimmune diseases
C Beeton, MW Pennington, H Wulff, S Singh, D Nugent, G Crossley, ...
Molecular pharmacology 67 (4), 1369-1381, 2005
3392005
Molecular properties and physiological roles of ion channels in the immune system
MD Cahalan, H Wulff, KG Chandy
Journal of clinical immunology 21, 235-252, 2001
3242001
Amyloid-β protein oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity
I Maezawa, PI Zimin, H Wulff, LW Jin
Journal of Biological Chemistry 286 (5), 3693-3706, 2011
3232011
The concise guide to pharmacology 2017/18: overview
SPH Alexander, E Kelly, NV Marrion, JA Peters, E Faccenda, SD Harding, ...
British journal of pharmacology 174, S1-S16, 2017
3072017
Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis
R Köhler, H Wulff, I Eichler, M Kneifel, D Neumann, A Knorr, I Grgic, ...
Circulation 108 (9), 1119-1125, 2003
2952003
Design of PAP-1, a selective small molecule Kv1. 3 blocker, for the suppression of effector memory T cells in autoimmune diseases
A Schmitz, A Sankaranarayanan, P Azam, K Schmidt-Lassen, D Homerick, ...
Molecular pharmacology 68 (5), 1254-1270, 2005
2782005
Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension
S Brähler, A Kaistha, VJ Schmidt, SE Wölfle, C Busch, BP Kaistha, ...
Circulation 119 (17), 2323-2332, 2009
2682009
K+ channel expression during B cell differentiation: implications for immunomodulation and autoimmunity
H Wulff, HG Knaus, M Pennington, KG Chandy
The Journal of Immunology 173 (2), 776-786, 2004
2632004
A non-hallucinogenic psychedelic analogue with therapeutic potential
LP Cameron, RJ Tombari, J Lu, AJ Pell, ZQ Hurley, Y Ehinger, MV Vargas, ...
Nature 589 (7842), 474-479, 2021
2622021
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Artículos 1–20