| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10721 | 2021 |
| Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis SC Ling, M Polymenidou, DW Cleveland Neuron 79 (3), 416-438, 2013 | 1759 | 2013 |
| Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43 M Polymenidou, C Lagier-Tourenne, KR Hutt, SC Huelga, J Moran, ... Nature neuroscience 14 (4), 459-468, 2011 | 1352 | 2011 |
| Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs C Lagier-Tourenne, M Polymenidou, KR Hutt, AQ Vu, M Baughn, ... Nature neuroscience 15 (11), 1488-1497, 2012 | 805 | 2012 |
| Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration C Lagier-Tourenne, M Baughn, F Rigo, S Sun, P Liu, HR Li, J Jiang, ... Proceedings of the National Academy of Sciences 110 (47), E4530-E4539, 2013 | 662 | 2013 |
| Gain of toxicity from ALS/FTD-linked repeat expansions in C9ORF72 is alleviated by antisense oligonucleotides targeting GGGGCC-containing RNAs J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ... Neuron 90 (3), 535-550, 2016 | 558 | 2016 |
| ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS SC Ling, CP Albuquerque, JS Han, C Lagier-Tourenne, S Tokunaga, ... Proceedings of the National Academy of Sciences 107 (30), 13318-13323, 2010 | 515 | 2010 |
| ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43 ES Arnold, SC Ling, SC Huelga, C Lagier-Tourenne, M Polymenidou, ... Proceedings of the National Academy of Sciences 110 (8), E736-E745, 2013 | 489 | 2013 |
| ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP S Sun, SC Ling, J Qiu, CP Albuquerque, Y Zhou, S Tokunaga, H Li, H Qiu, ... Nature communications 6 (1), 6171, 2015 | 240 | 2015 |
| Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein SC Ling, PS Fahrner, WT Greenough, VI Gelfand Proceedings of the National Academy of Sciences 101 (50), 17428-17433, 2004 | 221 | 2004 |
| ALS/FTD-linked mutation in FUS suppresses intra-axonal protein synthesis and drives disease without nuclear loss-of-function of FUS J López-Erauskin, T Tadokoro, MW Baughn, B Myers, ... Neuron 100 (4), 816-830. e7, 2018 | 204 | 2018 |
| Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS S Sun, Y Sun, SC Ling, L Ferraiuolo, M McAlonis-Downes, Y Zou, ... Proceedings of the National Academy of Sciences 112 (50), E6993-E7002, 2015 | 182 | 2015 |
| Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy CJ Cortes, SC Ling, LT Guo, G Hung, T Tsunemi, L Ly, S Tokunaga, ... Neuron 82 (2), 295-307, 2014 | 166 | 2014 |
| Microtubule binding by dynactin is required for microtubule organization but not cargo transport H Kim, SC Ling, GC Rogers, C Kural, PR Selvin, SL Rogers, VI Gelfand The Journal of cell biology 176 (5), 641-651, 2007 | 162 | 2007 |
| Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice*♦ TA Shelkovnikova, OM Peters, AV Deykin, N Connor-Robson, ... Journal of biological chemistry 288 (35), 25266-25274, 2013 | 143 | 2013 |
| Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS JC Mitchell, R Constable, E So, C Vance, E Scotter, L Glover, ... Acta neuropathologica communications 3, 1-16, 2015 | 99 | 2015 |
| A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons F Angenstein, AM Evans, RE Settlage, ST Moran, SC Ling, AY Klintsova, ... Journal of Neuroscience 22 (20), 8827-8837, 2002 | 98 | 2002 |
| Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination J Wang, WY Ho, K Lim, J Feng, G Tucker-Kellogg, KA Nave, SC Ling Proceedings of the National Academy of Sciences 115 (46), E10941-E10950, 2018 | 76 | 2018 |
| Synaptic paths to neurodegeneration: the emerging role of TDP-43 and FUS in synaptic functions SC Ling Neural plasticity 2018, 2018 | 74 | 2018 |
| Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis SC Ling, SG Dastidar, S Tokunaga, WY Ho, K Lim, H Ilieva, PA Parone, ... elife 8, e40811, 2019 | 73 | 2019 |
Don W ClevelandUniversity of California at San DiegoDirección de correo verificada de UCSD.EDU
