| A practical improvement, enhancing the large-scale synthesis of (+)-discodermolide: a third-generation approach AB Smith, BS Freeze, I Brouard, T Hirose Organic Letters 5 (23), 4405-4408, 2003 | 72 | 2003 |
| A new lupene triterpenetriol and anticholinesterase activity of Salvia sclareoides AP Rauter, I Branco, RG Lopes, J Justino, FVM Silva, JP Noronha, ... Fitoterapia 78 (7-8), 474-481, 2007 | 67 | 2007 |
| Toward understanding how the lactone moiety of discodermolide affects activity SJ Shaw, KF Sundermann, MA Burlingame, DC Myles, BS Freeze, M Xian, ... Journal of the American Chemical Society 127 (18), 6532-6533, 2005 | 64 | 2005 |
| Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide AB Smith, BS Freeze, MJ LaMarche, T Hirose, I Brouard, PV Rucker, ... Organic Letters 7 (2), 311-314, 2005 | 56 | 2005 |
| Cytotoxic sesquiterpene lactones and other constituents of Centaurea omphalotricha EH Kolli, F León, F Benayache, S Estévez, J Quintana, F Estévez, ... Journal of the Brazilian Chemical Society 23, 977-983, 2012 | 55 | 2012 |
| Synthesis and effects on cell viability of flavonols and 3-methyl ether derivatives on human leukemia cells O Burmistrova, MT Marrero, S Estévez, I Welsch, I Brouard, J Quintana, ... European journal of medicinal chemistry 84, 30-41, 2014 | 48 | 2014 |
| ‘Click’synthesis of triazole-based spirostan saponin analogs K Pérez-Labrada, I Brouard, C Morera, F Estévez, J Bermejo, DG Rivera Tetrahedron 67 (40), 7713-7727, 2011 | 48 | 2011 |
| A new flavonoid and other constituents from Centaurea nicaeensis All. var. walliana M. L Hammoud, R Seghiri, S Benayache, P Mosset, A Lobstein, M Chaabi, ... Natural Product Research 26 (3), 203-208, 2012 | 46 | 2012 |
| Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide AB Smith, BS Freeze, MJ LaMarche, T Hirose, I Brouard, M Xian, ... Organic letters 7 (2), 315-318, 2005 | 46 | 2005 |
| Multicomponent synthesis of Ugi-type ceramide analogues and neoglycolipids from lipidic isocyanides K Pérez-Labrada, I Brouard, I Méndez, DG Rivera The Journal of Organic Chemistry 77 (10), 4660-4670, 2012 | 43 | 2012 |
| Synthesis and biological studies of flexible brevetoxin/ciguatoxin models with marked conformational preference ML Candenas, FM Pinto, CG Cintado, EQ Morales, I Brouard, MT Dı́az, ... Tetrahedron 58 (10), 1921-1942, 2002 | 41 | 2002 |
| A facile chemoselective deacetylation in the presence of benzoyl and p-bromobenzoyl groups using p-toluenesulfonic acid AG González, I Brouard, F León, JI Padrón, J Bermejo Tetrahedron Letters 42 (18), 3187-3188, 2001 | 38 | 2001 |
| A chemotaxonomic study of endemic species of genus Tanacetum from the Canary Islands J Triana, JL Eiroa, M Morales, FJ Pérez, I Brouard, MT Marrero, S Estévez, ... Phytochemistry 92, 87-104, 2013 | 37 | 2013 |
| A New Ceramide from Suillus luteus and Its Cytotoxic Activity against Human Melanoma Cells F Leon, I Brouard, F Torres, J Quintana, A Rivera, F Estevez, J Bermejo Chemistry & Biodiversity 5 (1), 120-125, 2008 | 34 | 2008 |
| Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes AB Smith, PV Rucker, I Brouard, BS Freeze, S Xia, SB Horwitz Organic letters 7 (23), 5199-5202, 2005 | 33 | 2005 |
| Sesquiterpene lactones and other constituents from Matricaria chamomilla L. L Zaiter, M Bouheroum, S Benayache, F Benayache, F León, I Brouard, ... Biochemical systematics and ecology 35 (8), 533-538, 2007 | 31 | 2007 |
| Maroccanin: A New g-lactone and Other Constituents from Centaurea maroccana Ball.(Asteraceae) S Bicha, P Chalard, L Hammoud, F León, I Brouard, VP Garcia, ... Records of Natural Products 7 (2), 114, 2013 | 28 | 2013 |
| A new labdane diterpene and other constituents from Marrubium deserti Noe ex coss H Dendougui, S Seghir, Z Belloum, F Benayache, F Leon, I Brouard, ... ACG Publications, 2011 | 28 | 2011 |
| Flavonoids of Campanula alata and their antioxidant activity O Touafek, Z Kabouche, I Brouard, J Barrera Bermejo Chemistry of Natural Compounds 46, 968-970, 2011 | 28 | 2011 |
| New insights into the structure–cytotoxicity relationship of spirostan saponins and related glycosides K Pérez-Labrada, I Brouard, S Estévez, MT Marrero, F Estévez, J Bermejo, ... Bioorganic & medicinal chemistry 20 (8), 2690-2700, 2012 | 27 | 2012 |
