Pharmacological effects of berberine and its derivatives: a patent update Y Jin, DB Khadka, WJ Cho Expert opinion on therapeutic patents 26 (2), 229-243, 2016 | 147 | 2016 |
A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis YH Han, KO Shin, JY Kim, DB Khadka, HJ Kim, YM Lee, WJ Cho, JY Cha, ... The Journal of clinical investigation 129 (4), 1684-1698, 2019 | 128 | 2019 |
Topoisomerase inhibitors as anticancer agents: a patent update DB Khadka, WJ Cho Expert opinion on therapeutic patents 23 (8), 1033-1056, 2013 | 91 | 2013 |
3-Arylisoquinolines as novel topoisomerase I inhibitors DB Khadka, WJ Cho Bioorganic & Medicinal Chemistry 19 (2), 724-734, 2011 | 68 | 2011 |
Virtual screening and synthesis of quinazolines as novel JAK2 inhibitors SH Yang, DB Khadka, SH Cho, HK Ju, KY Lee, HJ Han, KT Lee, WJ Cho Bioorganic & Medicinal Chemistry 19 (2), 968-977, 2011 | 60 | 2011 |
Structure-based Virtual Screening and Identification of a Novel Androgen Receptor Antagonist CH Song, SH Yang, E Park, SH Cho, EY Gong, DB Khadka, WJ Cho, ... Journal of Biological Chemistry 287 (36), 30769-30780, 2012 | 44 | 2012 |
SAR Based Design of Nicotinamides as a Novel Class of Androgen Receptor Antagonists for Prostate Cancer SH Yang, CH Song, HTM Van, E Park, DB Khadka, EY Gong, K Lee, ... Journal of medicinal chemistry 56 (8), 3414-3418, 2013 | 33 | 2013 |
Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents SH Yang, HTM Van, TN Le, DB Khadka, SH Cho, KT Lee, HJ Chung, ... Bioorganic & medicinal chemistry letters 20 (17), 5277-5281, 2010 | 31 | 2010 |
Synthesis of 12-oxobenzo[c]phenanthridinones and 4-substituted 3-arylisoquinolones via Vilsmeier–Haack reaction DB Khadka, SH Yang, SH Cho, C Zhao, WJ Cho Tetrahedron 68 (1), 250-261, 2012 | 30 | 2012 |
Total synthesis of 8-oxypseudopalmatine and 8-oxypseudoberberine via ring-closing metathesis HTM Van, SH Yang, DB Khadka, YC Kim, WJ Cho Tetrahedron 65 (49), 10142-10148, 2009 | 30 | 2009 |
Synthesis of Aryl Trimethylstannane via BF3·OEt2-Mediated Cross-Coupling of Hexaalkyl Distannane Reagent with Aryl Triazene at Room Temperature S Mao, Z Chen, L Wang, DB Khadka, M Xin, P Li, SQ Zhang The Journal of organic chemistry 84 (1), 463-471, 2018 | 28 | 2018 |
Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors HTM Van, H Woo, HM Jeong, DB Khadka, SH Yang, C Zhao, Y Jin, ... European journal of medicinal chemistry 82, 181-194, 2014 | 28 | 2014 |
Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA SH Yang, HTM Van, TN Le, DB Khadka, SH Cho, KT Lee, ES Lee, YB Lee, ... European journal of medicinal chemistry 45 (11), 5493-5497, 2010 | 27 | 2010 |
Modification of 3-arylisoquinolines into 3, 4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition DB Khadka, H Woo, SH Yang, C Zhao, Y Jin, TN Le, Y Kwon, WJ Cho European journal of medicinal chemistry 92, 583-607, 2015 | 26 | 2015 |
Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases DB Khadka, GH Tran, S Shin, HTM Nguyen, HT Cao, C Zhao, Y Jin, ... European Journal of Medicinal Chemistry 103, 69-79, 2015 | 21 | 2015 |
Structure-based discovery of novel cyclophilin A inhibitors for the treatment of hepatitis C virus infections S Yang, J KR, S Lim, TG Choi, JH Kim, S Akter, M Jang, HJ Ahn, HY Kim, ... Journal of medicinal chemistry 58 (24), 9546-9561, 2015 | 20 | 2015 |
Berberine bioisostere Q8 compound stimulates osteoblast differentiation and function in vitro Y Han, Y Jin, SH Lee, DB Khadka, WJ Cho, KY Lee Pharmacological Research 119, 463-475, 2017 | 19 | 2017 |
Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling TN Le, SH Yang, DB Khadka, HTM Van, SH Cho, Y Kwon, ES Lee, ... Bioorganic & medicinal chemistry 19 (14), 4399-4404, 2011 | 19 | 2011 |
Triple reuptake inhibitors: Design, synthesis and structure–activity relationship of benzylpiperidine–tetrazoles S Paudel, X Min, S Acharya, DB Khadka, G Yoon, KM Kim, SH Cheon Bioorganic & medicinal chemistry 25 (20), 5278-5289, 2017 | 17 | 2017 |
Synthesis of benzo [3,4] azepino [1,2-b] isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity … HTM Van, DB Khadka, SH Yang, TN Le, SH Cho, C Zhao, IS Lee, Y Kwon, ... Bioorganic & medicinal chemistry 19 (18), 5311-5320, 2011 | 17 | 2011 |