Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10677 | 2021 |
Guidelines for the use and interpretation of assays for monitoring autophagy 1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... Autophagy 17 (1), 1, 2021 | 2738* | 2021 |
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease MR Ebrahimkhani, F Oakley, LB Murphy, J Mann, A Moles, MJ Perugorria, ... Nature medicine 17 (12), 1668-1673, 2011 | 225 | 2011 |
Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis N Tarrats, A Moles, A Morales, C García‐Ruiz, JC Fernández‐Checa, ... Hepatology 54 (1), 319-327, 2011 | 164 | 2011 |
A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse A Moles, L Murphy, CL Wilson, JB Chakraborty, C Fox, EJ Park, J Mann, ... Journal of hepatology 60 (4), 782-791, 2014 | 161 | 2014 |
Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-κB activation M Marí, A Colell, A Morales, F Caballero, A Moles, A Fernández, ... Gastroenterology 134 (5), 1507-1520, 2008 | 118 | 2008 |
Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans J Pritchett, E Harvey, V Athwal, A Berry, C Rowe, F Oakley, A Moles, ... Hepatology 56 (3), 1108-1116, 2012 | 111 | 2012 |
Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential A Moles, N Tarrats, JC Fernández‐Checa, M Marí Hepatology 49 (4), 1297-1307, 2009 | 109 | 2009 |
Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis A Moles, N Tarrats, A Morales, M Domínguez, R Bataller, J Caballería, ... The American journal of pathology 177 (3), 1214-1224, 2010 | 102 | 2010 |
Mitochondrial–lysosomal axis in acetaminophen hepatotoxicity A Moles, S Torres, A Baulies, C Garcia-Ruiz, JC Fernandez-Checa Frontiers in Pharmacology, 453, 2018 | 93 | 2018 |
The multifaceted role of the lysosomal protease cathepsins in kidney disease P Cocchiaro, V De Pasquale, R Della Morte, S Tafuri, L Avallone, A Pizard, ... Frontiers in cell and developmental biology 5, 114, 2017 | 80 | 2017 |
Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease C Fox, P Cocchiaro, F Oakley, R Howarth, K Callaghan, J Leslie, S Luli, ... Scientific Reports 6 (1), 1-15, 2016 | 69 | 2016 |
Cathepsin B overexpression due to acid sphingomyelinase ablation promotes liver fibrosis in Niemann-Pick disease A Moles, N Tarrats, JC Fernández-Checa, M Marí Journal of Biological Chemistry 287 (2), 1178-1188, 2012 | 66 | 2012 |
Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation Á De Mingo, E De Gregorio, A Moles, N Tarrats, A Tutusaus, A Colell, ... Cell death & disease 7 (11), e2464-e2464, 2016 | 57 | 2016 |
Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis J Martínez-Fábregas, A Prescott, S van Kasteren, DL Pedrioli, I McLean, ... Nature communications 9 (1), 1-16, 2018 | 51 | 2018 |
The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice N Fullard, A Moles, S O'Reilly, JM van Laar, D Faini, J Diboll, NJ Reynolds, ... The American journal of pathology 182 (6), 2109-2120, 2013 | 47 | 2013 |
Inhibition of RelA‐Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response A Moles, AM Sanchez, PS Banks, LB Murphy, S Luli, L Borthwick, A Fisher, ... Hepatology 57 (2), 817-828, 2013 | 43 | 2013 |
Alcohol, signaling, and ECM turnover D Seth, NB D’Souza El‐Guindy, M Apte, M Mari, S Dooley, M Neuman, ... Alcoholism: Clinical and Experimental Research 34 (1), 4-18, 2010 | 41 | 2010 |
Cathepsins in the pathophysiology of mucopolysaccharidoses: New perspectives for therapy V De Pasquale, A Moles, LM Pavone Cells 9 (4), 979, 2020 | 34 | 2020 |
A RelA (p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer A Moles, JA Butterworth, A Sanchez, JE Hunter, J Leslie, H Sellier, ... Oncogene 35 (35), 4623-4632, 2016 | 34 | 2016 |