| The genomic landscape of hypodiploid acute lymphoblastic leukemia L Holmfeldt, L Wei, E Diaz-Flores, M Walsh, J Zhang, L Ding, ... Nature genetics 45 (3), 242-252, 2013 | 784 | 2013 |
| Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates N Kotecha, NJ Flores, JM Irish, EF Simonds, DS Sakai, S Archambeault, ... Cancer cell 14 (4), 335-343, 2008 | 281 | 2008 |
| Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia V Frismantas, MP Dobay, A Rinaldi, J Tchinda, SH Dunn, J Kunz, ... Blood, The Journal of the American Society of Hematology 129 (11), e26-e37, 2017 | 215 | 2017 |
| p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal Z Zhao, J Zuber, E Diaz-Flores, L Lintault, SC Kogan, K Shannon, ... Genes & development 24 (13), 1389-1402, 2010 | 201 | 2010 |
| Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras JO Lauchle, D Kim, DT Le, K Akagi, M Crone, K Krisman, K Warner, ... Nature 461 (7262), 411-414, 2009 | 151 | 2009 |
| K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells MEM Van Meter, E Díaz-Flores, JA Archard, E Passegué, JM Irish, ... Blood 109 (9), 3945-3952, 2007 | 134 | 2007 |
| Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial N Jain, E Curran, NM Iyengar, E Diaz-Flores, R Kunnavakkam, ... Clinical cancer research 20 (2), 490-498, 2014 | 126 | 2014 |
| Diacylglycerol kinase inhibition prevents IL-2-induced G1 to S transition through a phosphatidylinositol-3 kinase-independent mechanism I Flores, DR Jones, A Ciprés, E Díaz-Flores, MA Sanjuan, I Mérida The Journal of Immunology 163 (2), 708-714, 1999 | 70 | 1999 |
| Bcl-2 is a therapeutic target for hypodiploid B-lineage acute lymphoblastic leukemia E Diaz-Flores, EQ Comeaux, KL Kim, E Melnik, K Beckman, KL Davis, ... Cancer research 79 (9), 2339-2351, 2019 | 69 | 2019 |
| Regulation of diacylglycerol kinase α by phosphoinositide 3-kinase lipid products A Ciprés, S Carrasco, E Merino, E Díaz, UM Krishna, JR Falck, ... Journal of Biological Chemistry 278 (37), 35629-35635, 2003 | 68 | 2003 |
| Targeting oncogenic ras E Diaz-Flores, K Shannon Genes & development 21 (16), 1989-1992, 2007 | 63 | 2007 |
| Abnormal hematopoiesis in Gab2 mutant mice Y Zhang, E Diaz-Flores, G Li, Z Wang, Z Kang, E Haviernikova, S Rowe, ... Blood, The Journal of the American Society of Hematology 110 (1), 116-124, 2007 | 48 | 2007 |
| Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis Z Zhao, CC Chen, CD Rillahan, R Shen, T Kitzing, ME McNerney, ... Nature genetics 47 (5), 539-543, 2015 | 47 | 2015 |
| β2-chimaerin provides a diacylglycerol-dependent mechanism for regulation of adhesion and chemotaxis of T cells M Siliceo, D García-Bernal, S Carrasco, E Díaz-Flores, FC Leskow, ... Journal of cell science 119 (1), 141-152, 2006 | 44 | 2006 |
| Membrane translocation of protein kinase Cθ during T lymphocyte activation requires phospholipase C-γ-generated diacylglycerol E Díaz-Flores, M Siliceo, C Martínez-A, I Mérida Journal of Biological Chemistry 278 (31), 29208-29215, 2003 | 44 | 2003 |
| Rapid screening of COVID‐19 patients using white blood cell scattergrams, a study on 381 patients J Osman, J Lambert, M Templé, F Devaux, R Favre, C Flaujac, D Bridoux, ... British Journal of Haematology 190 (5), 718-722, 2020 | 30 | 2020 |
| NRAS G12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia Z Sachs, RS LaRue, HT Nguyen, K Sachs, KE Noble, NA Mohd Hassan, ... Blood, The Journal of the American Society of Hematology 124 (22), 3274-3283, 2014 | 28 | 2014 |
| PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras E Diaz-Flores, H Goldschmidt, P Depeille, V Ng, J Akutagawa, K Krisman, ... Science signaling 6 (304), ra105-ra105, 2013 | 18 | 2013 |
| Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency Z Sachs, RA Been, KJ DeCoursin, HT Nguyen, NAM Hassan, ... Haematologica 101 (10), 1190, 2016 | 16 | 2016 |
| Interleukin-2 stimulates a late increase in phosphatidic acid production in the absence of phospholipase D activation DR Jones, I Flores, E Dı́az, C Martinez-A, I Mérida FEBS letters 433 (1-2), 23-27, 1998 | 13 | 1998 |
