Mauricio D Dorfman
Mauricio D Dorfman
Research Assistant Professor, Diabetes Institute, University of Washington
Dirección de correo verificada de uw.edu
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Microglial inflammatory signaling orchestrates the hypothalamic immune response to dietary excess and mediates obesity susceptibility
M Valdearcos, JD Douglass, MM Robblee, MD Dorfman, DR Stifler, ...
Cell metabolism 26 (1), 185-197. e3, 2017
1702017
Hypothalamic inflammation: marker or mechanism of obesity pathogenesis?
JP Thaler, SJ Guyenet, MD Dorfman, BE Wisse, MW Schwartz
Diabetes 62 (8), 2629-2634, 2013
1612013
Changes in sympathetic nerve activity of the mammalian ovary during a normal estrous cycle and in polycystic ovary syndrome: Studies on norepinephrine release
HE Lara, M Dorfman, M Venegas, SM Luza, SL Luna, A Mayerhofer, ...
Microscopy research and technique 59 (6), 495-502, 2002
1442002
Chronic intermittent cold stress activates ovarian sympathetic nerves and modifies ovarian follicular development in the rat
M Dorfman, S Arancibia, JL Fiedler, HE Lara
Biology of reproduction 68 (6), 2038-2043, 2003
972003
Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation
JD Douglass, MD Dorfman, R Fasnacht, LD Shaffer, JP Thaler
Molecular metabolism 6 (4), 366-373, 2017
952017
Neonatal exposure to estradiol valerate programs ovarian sympathetic innervation and follicular development in the adult rat
R Sotomayor-Zárate, M Dorfman, A Paredes, HE Lara
Biology of Reproduction 78 (4), 673-680, 2008
902008
Kisspeptin receptor haplo-insufficiency causes premature ovarian failure despite preserved gonadotropin secretion
F Gaytan, D Garcia-Galiano, MD Dorfman, M Manfredi-Lozano, ...
Endocrinology 155 (8), 3088-3097, 2014
742014
Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents
JM Scarlett, JM Rojas, ME Matsen, KJ Kaiyala, D Stefanovski, ...
Nature medicine 22 (7), 800-806, 2016
732016
Hypothalamic inflammation and gliosis in obesity
MD Dorfman, JP Thaler
Current opinion in endocrinology, diabetes, and obesity 22 (5), 325, 2015
722015
Functional identification of a neurocircuit regulating blood glucose
TH Meek, JT Nelson, ME Matsen, MD Dorfman, SJ Guyenet, V Damian, ...
Proceedings of the National Academy of Sciences 113 (14), E2073-E2082, 2016
662016
TrkA and TrkB receptors facilitate follicle assembly and early follicular development in the mouse ovary
B Kerr, C Garcia-Rudaz, M Dorfman, A Paredes, SR Ojeda
Reproduction (Cambridge, England) 138 (1), 131, 2009
662009
Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice
MD Dorfman, JE Krull, JD Douglass, R Fasnacht, F Lara-Lince, TH Meek, ...
Nature communications 8 (1), 1-11, 2017
652017
Loss of Ntrk2/Kiss1r Signaling in Oocytes Causes Premature Ovarian Failure
MD Dorfman, C Garcia-Rudaz, Z Alderman, B Kerr, A Lomniczi, ...
Endocrinology 155 (8), 3098-3111, 2014
582014
Cold stress induces metabolic activation of thyrotrophin‐releasing hormone‐synthesising neurones in the magnocellular division of the hypothalamic paraventricular nucleus and …
J Fiedler, P Jara, S Luza, M Dorfman, D Grouselle, F Rage, HE Lara, ...
Journal of neuroendocrinology 18 (5), 367-376, 2006
402006
Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia
TH Meek, ME Matsen, MD Dorfman, SJ Guyenet, V Damian, HT Nguyen, ...
Endocrinology 154 (9), 3067-3076, 2013
382013
Glia: silent partners in energy homeostasis and obesity pathogenesis
JD Douglass, MD Dorfman, JP Thaler
Diabetologia 60 (2), 226-236, 2017
372017
Chronic-intermittent cold stress in rats induces selective ovarian insulin resistance
M Dorfman, VD Ramirez, E Stener-Victorin, HE Lara
Biology of reproduction 80 (2), 264-271, 2009
272009
Evidence that in uncontrolled diabetes, hyperglucagonemia is required for ketosis but not for increased hepatic glucose production or hyperglycemia
TH Meek, MD Dorfman, ME Matsen, JD Fischer, A Cubelo, MR Kumar, ...
Diabetes 64 (7), 2376-2387, 2015
242015
Neurotrophins acting via TRKB receptors activate the JAGGED1-NOTCH2 cell-cell communication pathway to facilitate early ovarian development
MD Dorfman, B Kerr, C Garcia-Rudaz, AH Paredes, GA Dissen, SR Ojeda
Endocrinology 152 (12), 5005-5016, 2011
232011
Cell and molecular mechanisms behind diet‐induced hypothalamic inflammation and obesity
Y Ávalos, B Kerr, M Maliqueo, M Dorfman
Journal of neuroendocrinology 30 (10), e12598, 2018
182018
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Artículos 1–20