Mauricio D Dorfman
Mauricio D Dorfman
Research Assistant Professor, Diabetes Institute, University of Washington
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Microglial inflammatory signaling orchestrates the hypothalamic immune response to dietary excess and mediates obesity susceptibility
M Valdearcos, JD Douglass, MM Robblee, MD Dorfman, DR Stifler, ...
Cell metabolism 26 (1), 185-197. e3, 2017
Hypothalamic inflammation: marker or mechanism of obesity pathogenesis?
JP Thaler, SJ Guyenet, MD Dorfman, BE Wisse, MW Schwartz
Diabetes 62 (8), 2629-2634, 2013
Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation
JD Douglass, MD Dorfman, R Fasnacht, LD Shaffer, JP Thaler
Molecular metabolism 6 (4), 366-373, 2017
Changes in sympathetic nerve activity of the mammalian ovary during a normal estrous cycle and in polycystic ovary syndrome: Studies on norepinephrine release
HE Lara, M Dorfman, M Venegas, SM Luza, SL Luna, A Mayerhofer, ...
Microscopy research and technique 59 (6), 495-502, 2002
Functional identification of a neurocircuit regulating blood glucose
TH Meek, JT Nelson, ME Matsen, MD Dorfman, SJ Guyenet, V Damian, ...
Proceedings of the National Academy of Sciences 113 (14), E2073-E2082, 2016
Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents
JM Scarlett, JM Rojas, ME Matsen, KJ Kaiyala, D Stefanovski, ...
Nature medicine 22 (7), 800-806, 2016
Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice
MD Dorfman, JE Krull, JD Douglass, R Fasnacht, F Lara-Lince, TH Meek, ...
Nature communications 8 (1), 14556, 2017
Hypothalamic inflammation and gliosis in obesity
MD Dorfman, JP Thaler
Current opinion in endocrinology, diabetes, and obesity 22 (5), 325, 2015
Chronic intermittent cold stress activates ovarian sympathetic nerves and modifies ovarian follicular development in the rat
M Dorfman, S Arancibia, JL Fiedler, HE Lara
Biology of reproduction 68 (6), 2038-2043, 2003
Kisspeptin receptor haplo-insufficiency causes premature ovarian failure despite preserved gonadotropin secretion
F Gaytan, D Garcia-Galiano, MD Dorfman, M Manfredi-Lozano, ...
Endocrinology 155 (8), 3088-3097, 2014
Neonatal exposure to estradiol valerate programs ovarian sympathetic innervation and follicular development in the adult rat
R Sotomayor-Zárate, M Dorfman, A Paredes, HE Lara
Biology of Reproduction 78 (4), 673-680, 2008
TrkA and TrkB receptors facilitate follicle assembly and early follicular development in the mouse ovary
B Kerr, C Garcia-Rudaz, M Dorfman, A Paredes, SR Ojeda
Reproduction (Cambridge, England) 138 (1), 131, 2009
Loss of Ntrk2/Kiss1r Signaling in Oocytes Causes Premature Ovarian Failure
MD Dorfman, C Garcia-Rudaz, Z Alderman, B Kerr, A Lomniczi, ...
Endocrinology 155 (8), 3098-3111, 2014
Glia: silent partners in energy homeostasis and obesity pathogenesis
JD Douglass, MD Dorfman, JP Thaler
Diabetologia 60 (2), 226-236, 2017
Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia
TH Meek, ME Matsen, MD Dorfman, SJ Guyenet, V Damian, HT Nguyen, ...
Endocrinology 154 (9), 3067-3076, 2013
Cold stress induces metabolic activation of thyrotrophin‐releasing hormone‐synthesising neurones in the magnocellular division of the hypothalamic paraventricular nucleus and …
J Fiedler, P Jara, S Luza, M Dorfman, D Grouselle, F Rage, HE Lara, ...
Journal of neuroendocrinology 18 (5), 367-376, 2006
Cell and molecular mechanisms behind diet‐induced hypothalamic inflammation and obesity
Y Ávalos, B Kerr, M Maliqueo, M Dorfman
Journal of neuroendocrinology 30 (10), e12598, 2018
Chronic-intermittent cold stress in rats induces selective ovarian insulin resistance
M Dorfman, VD Ramirez, E Stener-Victorin, HE Lara
Biology of reproduction 80 (2), 264-271, 2009
Evidence that in uncontrolled diabetes, hyperglucagonemia is required for ketosis but not for increased hepatic glucose production or hyperglycemia
TH Meek, MD Dorfman, ME Matsen, JD Fischer, A Cubelo, MR Kumar, ...
Diabetes 64 (7), 2376-2387, 2015
Neurotrophins acting via TRKB receptors activate the JAGGED1-NOTCH2 cell-cell communication pathway to facilitate early ovarian development
MD Dorfman, B Kerr, C Garcia-Rudaz, AH Paredes, GA Dissen, SR Ojeda
Endocrinology 152 (12), 5005-5016, 2011
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