Isolation and structure of a brain constituent that binds to the cannabinoid receptor WA Devane, L Hanuš, A Breuer, RG Pertwee, LA Stevenson, G Griffin, ... Science 258 (5090), 1946-1949, 1992 | 7078 | 1992 |
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors R Mechoulam, S Ben-Shabat, L Hanus, M Ligumsky, NE Kaminski, ... Biochemical pharmacology 50 (1), 83-90, 1995 | 3645 | 1995 |
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors AC Howlett, F Barth, TI Bonner, G Cabral, P Casellas, WA Devane, ... Pharmacological reviews 54 (2), 161-202, 2002 | 3523 | 2002 |
Isolation, structure, and partial synthesis of an active constituent of hashish Y Gaoni, R Mechoulam Journal of the American chemical society 86 (8), 1646-1647, 1964 | 3424 | 1964 |
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2 RG Pertwee, AC Howlett, ME Abood, SPH Alexander, V Di Marzo, ... Pharmacological reviews 62 (4), 588-631, 2010 | 1899 | 2010 |
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide T Bisogno, L Hanuš, L De Petrocellis, S Tchilibon, DE Ponde, I Brandi, ... British journal of pharmacology 134 (4), 845-852, 2001 | 1289 | 2001 |
The endocannabinoid system and the brain R Mechoulam, LA Parker Annual review of psychology 64, 21-47, 2013 | 1199 | 2013 |
2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor L Hanuš, S Abu-Lafi, E Fride, A Breuer, Z Vogel, DE Shalev, I Kustanovich, ... Proceedings of the National Academy of Sciences 98 (7), 3662-3665, 2001 | 1043 | 2001 |
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb AA Izzo, F Borrelli, R Capasso, V Di Marzo, R Mechoulam Trends in pharmacological sciences 30 (10), 515-527, 2009 | 1013 | 2009 |
An endogenous cannabinoid (2-AG) is neuroprotective after brain injury D Panikashvili, C Simeonidou, S Ben-Shabat, L Hanuš, A Breuer, ... Nature 413 (6855), 527-531, 2001 | 908 | 2001 |
A Total Synthesis of dl-Δ1-Tetrahydrocannabinol, the Active Constituent of Hashish1 R Mechoulam, Y Gaoni Journal of the American Chemical Society 87 (14), 3273-3275, 1965 | 821* | 1965 |
Chronic administration of cannabidiol to healthy volunteers and epileptic patients JM Cunha, EA Carlini, AE Pereira, OL Ramos, C Pimentel, R Gagliardi, ... Pharmacology 21 (3), 175-185, 1980 | 805 | 1980 |
The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis AM Malfait, R Gallily, PF Sumariwalla, AS Malik, E Andreakos, ... Proceedings of the National Academy of Sciences 97 (17), 9561-9566, 2000 | 791 | 2000 |
Marihuana Chemistry: Recent advances in cannabinoid chemistry open the area to more sophisticated biological research. R Mechoulam Science 168 (3936), 1159-1166, 1970 | 777 | 1970 |
HU-308: A specific agonist for CB2, a peripheral cannabinoid receptor L Hanuš, A Breuer, S Tchilibon, S Shiloah, D Goldenberg, M Horowitz, ... Proceedings of the National Academy of Sciences 96 (25), 14228-14233, 1999 | 738 | 1999 |
An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity S Ben-Shabat, E Fride, T Sheskin, T Tamiri, MH Rhee, Z Vogel, T Bisogno, ... European journal of pharmacology 353 (1), 23-31, 1998 | 722 | 1998 |
Endocannabinoid signaling at the periphery: 50 years after THC M Maccarrone, I Bab, T Bíró, GA Cabral, SK Dey, V Di Marzo, JC Konje, ... Trends in pharmacological sciences 36 (5), 277-296, 2015 | 702 | 2015 |
Cannabidiol–recent advances R Mechoulam, M Peters, E Murillo‐Rodriguez, LO Hanuš Chemistry & biodiversity 4 (8), 1678-1692, 2007 | 663 | 2007 |
Endocannabinoids R Mechoulam, E Fride, V Di Marzo European journal of pharmacology 359 (1), 1-18, 1998 | 656 | 1998 |
Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent E Fride, R Mechoulam European journal of pharmacology 231 (2), 313-314, 1993 | 639 | 1993 |