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Paul William Finn
Paul William Finn
Oxford Drug Design Limited, University of Buckingham, Affinity Drug Design
Dirección de correo verificada de oxforddrugdesign.com
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Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
N Khan, M Jeffers, S Kumar, C Hackett, F Boldog, N Khramtsov, X Qian, ...
Biochemical Journal 409 (2), 581-589, 2008
8572008
Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101
JA Plumb, PW Finn, RJ Williams, MJ Bandara, MR Romero, CJ Watkins, ...
Molecular cancer therapeutics 2 (8), 721-728, 2003
4512003
Quantitative proteomic analysis of post-translational modifications of human histones
HC Beck, EC Nielsen, R Matthiesen, LH Jensen, M Sehested, P Finn, ...
Molecular & Cellular Proteomics 5 (7), 1314-1325, 2006
2302006
Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo
N Steele, P Finn, R Brown, JA Plumb
British journal of cancer 100 (5), 758-763, 2009
1862009
Pharmacophore discovery using the inductive logic programming system Progol
P Finn, S Muggleton, D Page, A Srinivasan
Machine Learning 30, 241-270, 1998
1701998
Carbamic acid compounds comprising an amide linkage as HDAC inhibitors
A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ...
US Patent 7,880,020, 2011
122*2011
ElectroShape: fast molecular similarity calculations incorporating shape, chirality and electrostatics
MS Armstrong, GM Morris, PW Finn, R Sharma, L Moretti, RI Cooper, ...
Journal of computer-aided molecular design 24, 789-801, 2010
1152010
Carbamic acid compounds comprising an amide linkage as hdac inhibitors
A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ...
US Patent App. 12/983,971, 2011
110*2011
Carbamic acid compounds comprising an amide linkage as HDAC inhibitors
A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ...
US Patent 7,569,724, 2009
108*2009
RAPID: Randomized pharmacophore identification for drug design
PW Finn, LE Kavraki, JC Latombe, M R, C Shelton, ...
Computational Geometry: Theory and Applications 4 (10), 263-272, 1998
981998
Rapid: Randomized pharmacophore identification for drug design
PW Finn, LE Kavraki, JC Latombe, R Motwani, C Shelton, ...
Proceedings of the thirteenth annual symposium on Computational geometry …, 1997
981997
Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
CJ Watkins, MR Romero-Martin, KG Moore, J Ritchie, PW Finn, I Kalvinsh, ...
US Patent 6,888,027, 2005
972005
Ultrafast shape recognition: evaluating a new ligand-based virtual screening technology
PJ Ballester, PW Finn, WG Richards
Journal of Molecular Graphics and Modelling 27 (7), 836-845, 2009
962009
The cell cycle, chromatin and cancer: mechanism-based therapeutics come of age
F McLaughlin, P Finn, NB La Thangue
Drug discovery today 8 (17), 793-802, 2003
872003
Carbamic acid compounds comprising an ether linkage as HDAC inhibitors
CJ Watkins, MR Romero-Martin, PW Finn, I Kalvinsh, E Loza, D Lolya, ...
US Patent 6,960,685, 2005
832005
Carbamic acid compounds comprising an ether linkage as HDAC inhibitors
RM Bokaldere, JES Duffy, PW Finn, CJ Harris, I Kalvinsh, D Lolya, E Loza, ...
US Patent 6,960,685, 2005
83*2005
Carbamic acid compounds comprising an amide linkage as HDAC inhibitors
CJ Watkins, MR Romero-Martin, KG Moore, J Ritchie, PW Finn, I Kalvinsh, ...
US Patent 7,569,724, 2009
822009
Computational approaches to drug design
PW Finn, LE Kavraki
Algorithmica 25, 347-371, 1999
781999
Carbamic acid compounds comprising an amide linkage as HDAC inhibitors
CJ Watkins, MR Romero-Martin, KG Moore, J Ritchie, PW Finn, I Kalvinsh, ...
US Patent 7,569,724, 2009
772009
Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
CJ Watkins, MR Romero-Martin, KG Moore, J Ritchie, PW Finn, I Kalvinsh, ...
US Patent 6,888,027, 2005
772005
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