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Heikki Takala
Heikki Takala
Academy of Finland Research Fellow, University of Jyväskylä
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Signal amplification and transduction in phytochrome photosensors
H Takala, A Björling, O Berntsson, H Lehtivuori, S Niebling, M Hoernke, ...
Nature 509 (7499), 245-248, 2014
3582014
β2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding
H Takala, E Nurminen, SM Nurmi, M Aatonen, T Strandin, M Takatalo, ...
Blood, The Journal of the American Society of Hematology 112 (5), 1853-1862, 2008
1892008
Structural photoactivation of a full-length bacterial phytochrome
A Björling, O Berntsson, H Lehtivuori, H Takala, AJ Hughes, M Panman, ...
Science Advances 2 (8), e1600920, 2016
1192016
The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser
E Claesson, WY Wahlgren, H Takala, S Pandey, L Castillon, ...
Elife 9, e53514, 2020
912020
Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase
O Berntsson, RP Diensthuber, MR Panman, A Björling, E Gustavsson, ...
Nature communications 8 (1), 284, 2017
692017
Light-induced changes in the dimerization interface of bacteriophytochromes
H Takala, A Björling, M Linna, S Westenhoff, JA Ihalainen
Journal of Biological Chemistry 290 (26), 16383-16392, 2015
622015
On the (un) coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome
H Takala, HK Lehtivuori, O Berntsson, A Hughes, R Nanekar, S Niebling, ...
Journal of Biological Chemistry 293 (21), 8161-8172, 2018
562018
Fluorescence Properties of the Chromophore-Binding Domain of Bacteriophytochrome from Deinococcus radiodurans
H Lehtivuori, I Rissanen, H Takala, J Bamford, NV Tkachenko, ...
The Journal of Physical Chemistry B 117 (38), 11049-11057, 2013
542013
The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography
P Edlund, H Takala, E Claesson, L Henry, R Dods, H Lehtivuori, ...
Scientific reports 6 (1), 35279, 2016
532016
Light-induced structural changes in a monomeric bacteriophytochrome
H Takala, S Niebling, O Berntsson, A Björling, H Lehtivuori, H Häkkänen, ...
Structural Dynamics 3 (5), 2016
412016
Ubiquitous structural signaling in bacterial phytochromes
A Bjorling, O Berntsson, H Takala, KD Gallagher, H Patel, E Gustavsson, ...
The journal of physical chemistry letters 6 (17), 3379-3383, 2015
402015
Tips and turns of bacteriophytochrome photoactivation
H Takala, P Edlund, JA Ihalainen, S Westenhoff
Photochemical & Photobiological Sciences 19 (11), 1488-1510, 2020
392020
Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome
NC Woitowich, AS Halavaty, P Waltz, C Kupitz, J Valera, G Tracy, ...
IUCrJ 5 (5), 619-634, 2018
392018
Connection between Absorption Properties and Conformational Changes in Deinococcus radiodurans Phytochrome
H Takala, H Lehtivuori, H Hammarén, VP Hytonen, JA Ihalainen
Biochemistry 53 (45), 7076-7085, 2014
352014
Coordination of the biliverdin D-ring in bacteriophytochromes
N Lenngren, P Edlund, H Takala, B Stucki-Buchli, J Rumfeldt, I Peshev, ...
Physical Chemistry Chemical Physics 20 (27), 18216-18225, 2018
312018
Red light optogenetics in neuroscience
K Lehtinen, MS Nokia, H Takala
Frontiers in Cellular Neuroscience 15, 778900, 2022
272022
Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling
E Multamäki, R Nanekar, D Morozov, T Lievonen, D Golonka, ...
Nature Communications 12 (1), 4394, 2021
272021
Assembly of a filamin four-domain fragment and the influence of splicing variant-1 on the structure
U Pentikäinen, P Jiang, H Takala, S Ruskamo, ID Campbell, J Ylänne
Journal of Biological Chemistry 286 (30), 26921-26930, 2011
232011
UV‐vis spectroscopy reveals a correlation between Y263 and BV protonation states in bacteriophytochromes
JA Rumfeldt, H Takala, A Liukkonen, JA Ihalainen
Photochemistry and Photobiology 95 (4), 969-979, 2019
202019
Structural mechanism of signal transduction in a phytochrome histidine kinase
WY Wahlgren, E Claesson, I Tuure, S Trillo-Muyo, S Bódizs, JA Ihalainen, ...
Nature Communications 13 (1), 7673, 2022
192022
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