Xiongbin Lu
Xiongbin Lu
Professor, Indiana University School of Medicine
Dirección de correo verificada de iu.edu
Citado por
Citado por
p53 mutant mice that display early ageing-associated phenotypes
SD Tyner, S Venkatachalam, J Choi, S Jones, N Ghebranious, ...
Nature 415 (6867), 45-53, 2002
PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints
X Lu, B Nannenga, LA Donehower
Genes & development 19 (10), 1162-1174, 2005
The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop
X Lu, O Ma, TA Nguyen, SN Jones, M Oren, LA Donehower
Cancer cell 12 (4), 342-354, 2007
The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways
X Lu, TA Nguyen, SH Moon, Y Darlington, M Sommer, LA Donehower
Cancer and Metastasis Reviews 27 (2), 123-135, 2008
The ATM kinase induces microRNA biogenesis in the DNA damage response
X Zhang, G Wan, FG Berger, X He, X Lu
Molecular cell 41 (4), 371-383, 2011
Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway
G Wan, R Mathur, X Hu, Y Liu, X Zhang, G Peng, X Lu
Cellular signalling 25 (5), 1086-1095, 2013
Chitosan-decorated doxorubicin-encapsulated nanoparticle targets and eliminates tumor reinitiating cancer stem-like cells
W Rao, H Wang, J Han, S Zhao, J Dumbleton, P Agarwal, W Zhang, ...
ACS nano 9 (6), 5725-5740, 2015
Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth
L Yang, A Achreja, TL Yeung, LS Mangala, D Jiang, C Han, J Baddour, ...
Cell metabolism 24 (5), 685-700, 2016
TP53 loss creates therapeutic vulnerability in colorectal cancer
Y Liu, X Zhang, C Han, G Wan, X Huang, C Ivan, D Jiang, ...
Nature 520 (7549), 697-701, 2015
USP4 inhibits p53 through deubiquitinating and stabilizing ARF‐BP1
X Zhang, FG Berger, J Yang, X Lu
The EMBO journal 30 (11), 2177-2189, 2011
Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway
X Zhang, G Wan, S Mlotshwa, V Vance, FG Berger, H Chen, X Lu
Cancer research 70 (18), 7176-7186, 2010
Drug resistance and new therapies in colorectal cancer
K Van der Jeught, HC Xu, YJ Li, XB Lu, G Ji
World journal of gastroenterology 24 (34), 3834, 2018
Hyaluronic acid-decorated dual responsive nanoparticles of Pluronic F127, PLGA, and chitosan for targeted co-delivery of doxorubicin and irinotecan to eliminate cancer stem …
H Wang, P Agarwal, S Zhao, RX Xu, J Yu, X Lu, X He
Biomaterials 72, 74-89, 2015
miRNA response to DNA damage
G Wan, R Mathur, X Hu, X Zhang, X Lu
Trends in biochemical sciences 36 (9), 478-484, 2011
miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase
Y Zhou, G Wan, R Spizzo, C Ivan, R Mathur, X Hu, X Ye, J Lu, F Fan, L Xia, ...
Molecular oncology 8 (1), 83-92, 2014
Synthesis and characterization of thermally responsive pluronic F127− chitosan nanocapsules for controlled release and intracellular delivery of small molecules
W Zhang, K Gilstrap, L Wu, RB KC, MA Moss, Q Wang, X Lu, X He
ACS nano 4 (11), 6747-6759, 2010
Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D
RC Castellino, M De Bortoli, X Lu, SH Moon, TA Nguyen, MA Shepard, ...
Journal of neuro-oncology 86 (3), 245-256, 2008
Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance
H Wang, Z Gao, X Liu, P Agarwal, S Zhao, DW Conroy, G Ji, J Yu, ...
Nature communications 9 (1), 1-16, 2018
USP4 targets TAK1 to downregulate TNF α-induced NF-κ B activation
YH Fan, Y Yu, RF Mao, XJ Tan, GF Xu, H Zhang, XB Lu, SB Fu, J Yang
Cell Death & Differentiation 18 (10), 1547-1560, 2011
The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair
X Lu, D Bocangel, B Nannenga, H Yamaguchi, E Appella, LA Donehower
Molecular cell 15 (4), 621-634, 2004
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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