Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration R Natoli, N Fernando, M Madigan, JA Chu-Tan, K Valter, J Provis, M Rutar Molecular neurodegeneration 12, 1-11, 2017 | 122 | 2017 |
Retinal macrophages synthesize C3 and activate complement in AMD and in models of focal retinal degeneration R Natoli, N Fernando, H Jiao, T Racic, M Madigan, NL Barnett, ... Investigative ophthalmology & visual science 58 (7), 2977-2990, 2017 | 90 | 2017 |
MicroRNA-124 dysregulation is associated with retinal inflammation and photoreceptor death in the degenerating retina JA Chu-Tan, M Rutar, K Saxena, R Aggio-Bruce, RW Essex, K Valter, ... Investigative ophthalmology & visual science 59 (10), 4094-4105, 2018 | 54 | 2018 |
Small-medium extracellular vesicles and their miRNA cargo in retinal health and degeneration: mediators of homeostasis, and vehicles for targeted gene therapy Y Wooff, AV Cioanca, JA Chu-Tan, R Aggio-Bruce, U Schumann, R Natoli Frontiers in cellular neuroscience 14, 160, 2020 | 49 | 2020 |
Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration Y Wooff, N Fernando, JHC Wong, C Dietrich, R Aggio-Bruce, JA Chu-Tan, ... Scientific Reports 10 (1), 2263, 2020 | 33 | 2020 |
Obesity-induced metabolic disturbance drives oxidative stress and complement activation in the retinal environment R Natoli, N Fernando, T Dahlenburg, H Jiao, R Aggio-Bruce, NL Barnett, ... Molecular vision 24, 201, 2018 | 26 | 2018 |
The role of pyruvate in protecting 661W photoreceptor-like cells against light-induced cell death R Natoli, M Rutar, YZ Lu, JA Chu-Tan, Y Chen, K Saxena, M Madigan, ... Current eye research 41 (11), 1473-1481, 2016 | 20 | 2016 |
Inhibition of microRNA-155 protects retinal function through attenuation of inflammation in retinal degeneration R Aggio-Bruce, JA Chu-Tan, Y Wooff, AV Cioanca, U Schumann, R Natoli Molecular neurobiology 58, 835-854, 2021 | 18 | 2021 |
MicroRNA-223 regulates retinal function and inflammation in the healthy and degenerating retina N Fernando, JHC Wong, S Das, C Dietrich, R Aggio-Bruce, AV Cioanca, ... Frontiers in Cell and Developmental Biology 8, 516, 2020 | 16 | 2020 |
Efficacy of 670 nm light therapy to protect against photoreceptor cell death is dependent on the severity of damage JA Chu-Tan, M Rutar, K Saxena, Y Wu, L Howitt, K Valter, J Provis, ... International Journal of Photoenergy 2016, 2016 | 16 | 2016 |
Functional microRNA targetome undergoes degeneration-induced shift in the retina JA Chu-Tan, AV Cioanca, ZP Feng, Y Wooff, U Schumann, R Aggio-Bruce, ... Molecular neurodegeneration 16 (1), 60, 2021 | 12 | 2021 |
Running to save sight: The effects of exercise on retinal health and function JA Chu‐Tan, M Kirkby, R Natoli Clinical & Experimental Ophthalmology 50 (1), 74-90, 2022 | 11 | 2022 |
Photoreceptor survival is regulated by GSTO1-1 in the degenerating retina N Fernando, Y Wooff, R Aggio-Bruce, JA Chu-Tan, H Jiao, C Dietrich, ... Investigative ophthalmology & visual science 59 (11), 4362-4374, 2018 | 11 | 2018 |
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration S Zeng, T Zhang, Y Chen, J Chu-Tan, K Jin, SR Lee, MX Yam, ... Theranostics 12 (15), 6705, 2022 | 10 | 2022 |
A method for gene knockdown in the retina using a lipid-based carrier JA Chu-Tan, N Fernando, R Aggio-Bruce, AV Cioanca, K Valter, ... Molecular vision 26, 48, 2020 | 10 | 2020 |
Short exposure to photo-oxidative damage triggers molecular signals indicative of early retinal degeneration Y Wooff, AV Cioanca, E Wills, JA Chu-Tan, R Sekar, R Natoli Frontiers in Immunology 14, 1088654, 2023 | 4 | 2023 |
The potential for microRNA-based therapeutics in retinal disorders JA Chu-Tan, R Natoli Annals of Translational Medicine 8 (7), 2020 | 3 | 2020 |
Functional microRNA targetome undergoes degeneration-induced shift in the retina JA Chu-Tan, ZP Feng, Y Wooff, AV Cioanca, U Schumann, R Aggio-Bruce, ... bioRxiv, 2020.05. 27.118307, 2020 | 1 | 2020 |
Forced exercise paradigm promotes decreased recruitment of retinal inflammatory cells and protects against retinal degeneration H Haupt, K Bales, GML Douglas, J Chu-Tan, R Natoli, JN Nickerson, ... Investigative Ophthalmology & Visual Science 64 (8), 4485-4485, 2023 | | 2023 |
Voluntary exercise modulates pathways associated with amelioration of retinal degenerative diseases JA Chu-Tan, AV Cioanca, Y Wooff, M Kirkby, M Ellis, P Gulati, T Karl, ... Frontiers in Physiology 14, 1116898, 2023 | | 2023 |