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Joshua Chu-Tan
Joshua Chu-Tan
Postdoctoral Fellow, The Australian National University
Dirección de correo verificada de anu.edu.au
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Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration
R Natoli, N Fernando, M Madigan, JA Chu-Tan, K Valter, J Provis, M Rutar
Molecular neurodegeneration 12, 1-11, 2017
1222017
Retinal macrophages synthesize C3 and activate complement in AMD and in models of focal retinal degeneration
R Natoli, N Fernando, H Jiao, T Racic, M Madigan, NL Barnett, ...
Investigative ophthalmology & visual science 58 (7), 2977-2990, 2017
902017
MicroRNA-124 dysregulation is associated with retinal inflammation and photoreceptor death in the degenerating retina
JA Chu-Tan, M Rutar, K Saxena, R Aggio-Bruce, RW Essex, K Valter, ...
Investigative ophthalmology & visual science 59 (10), 4094-4105, 2018
542018
Small-medium extracellular vesicles and their miRNA cargo in retinal health and degeneration: mediators of homeostasis, and vehicles for targeted gene therapy
Y Wooff, AV Cioanca, JA Chu-Tan, R Aggio-Bruce, U Schumann, R Natoli
Frontiers in cellular neuroscience 14, 160, 2020
492020
Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration
Y Wooff, N Fernando, JHC Wong, C Dietrich, R Aggio-Bruce, JA Chu-Tan, ...
Scientific Reports 10 (1), 2263, 2020
332020
Obesity-induced metabolic disturbance drives oxidative stress and complement activation in the retinal environment
R Natoli, N Fernando, T Dahlenburg, H Jiao, R Aggio-Bruce, NL Barnett, ...
Molecular vision 24, 201, 2018
262018
The role of pyruvate in protecting 661W photoreceptor-like cells against light-induced cell death
R Natoli, M Rutar, YZ Lu, JA Chu-Tan, Y Chen, K Saxena, M Madigan, ...
Current eye research 41 (11), 1473-1481, 2016
202016
Inhibition of microRNA-155 protects retinal function through attenuation of inflammation in retinal degeneration
R Aggio-Bruce, JA Chu-Tan, Y Wooff, AV Cioanca, U Schumann, R Natoli
Molecular neurobiology 58, 835-854, 2021
182021
MicroRNA-223 regulates retinal function and inflammation in the healthy and degenerating retina
N Fernando, JHC Wong, S Das, C Dietrich, R Aggio-Bruce, AV Cioanca, ...
Frontiers in Cell and Developmental Biology 8, 516, 2020
162020
Efficacy of 670 nm light therapy to protect against photoreceptor cell death is dependent on the severity of damage
JA Chu-Tan, M Rutar, K Saxena, Y Wu, L Howitt, K Valter, J Provis, ...
International Journal of Photoenergy 2016, 2016
162016
Functional microRNA targetome undergoes degeneration-induced shift in the retina
JA Chu-Tan, AV Cioanca, ZP Feng, Y Wooff, U Schumann, R Aggio-Bruce, ...
Molecular neurodegeneration 16 (1), 60, 2021
122021
Running to save sight: The effects of exercise on retinal health and function
JA Chu‐Tan, M Kirkby, R Natoli
Clinical & Experimental Ophthalmology 50 (1), 74-90, 2022
112022
Photoreceptor survival is regulated by GSTO1-1 in the degenerating retina
N Fernando, Y Wooff, R Aggio-Bruce, JA Chu-Tan, H Jiao, C Dietrich, ...
Investigative ophthalmology & visual science 59 (11), 4362-4374, 2018
112018
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration
S Zeng, T Zhang, Y Chen, J Chu-Tan, K Jin, SR Lee, MX Yam, ...
Theranostics 12 (15), 6705, 2022
102022
A method for gene knockdown in the retina using a lipid-based carrier
JA Chu-Tan, N Fernando, R Aggio-Bruce, AV Cioanca, K Valter, ...
Molecular vision 26, 48, 2020
102020
Short exposure to photo-oxidative damage triggers molecular signals indicative of early retinal degeneration
Y Wooff, AV Cioanca, E Wills, JA Chu-Tan, R Sekar, R Natoli
Frontiers in Immunology 14, 1088654, 2023
42023
The potential for microRNA-based therapeutics in retinal disorders
JA Chu-Tan, R Natoli
Annals of Translational Medicine 8 (7), 2020
32020
Functional microRNA targetome undergoes degeneration-induced shift in the retina
JA Chu-Tan, ZP Feng, Y Wooff, AV Cioanca, U Schumann, R Aggio-Bruce, ...
bioRxiv, 2020.05. 27.118307, 2020
12020
Forced exercise paradigm promotes decreased recruitment of retinal inflammatory cells and protects against retinal degeneration
H Haupt, K Bales, GML Douglas, J Chu-Tan, R Natoli, JN Nickerson, ...
Investigative Ophthalmology & Visual Science 64 (8), 4485-4485, 2023
2023
Voluntary exercise modulates pathways associated with amelioration of retinal degenerative diseases
JA Chu-Tan, AV Cioanca, Y Wooff, M Kirkby, M Ellis, P Gulati, T Karl, ...
Frontiers in Physiology 14, 1116898, 2023
2023
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