Charlotta Scharfe
Charlotta Scharfe
Graduate Student in Bioinformatics, University of Tubingen
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Sequence co-evolution gives 3D contacts and structures of protein complexes
TA Hopf, CPI Schärfe, JP Rodrigues, AG Green, O Kohlbacher, C Sander, ...
Elife 3, e03430, 2014
Mutation effects predicted from sequence co-variation
TA Hopf, JB Ingraham, FJ Poelwijk, CPI Schärfe, M Springer, C Sander, ...
Nature biotechnology 35 (2), 128, 2017
The MoSGrid science gateway–a complete solution for molecular simulations
J Krüger, R Grunzke, S Gesing, S Breuers, A Brinkmann, L de la Garza, ...
Journal of Chemical Theory and Computation 10 (6), 2232-2245, 2014
Activation of lymphoma-associated MyD88 mutations via allostery-induced TIR-domain oligomerization
M Avbelj, OO Wolz, O Fekonja, M Benčina, M Repič, J Mavri, J Krüger, ...
Blood, The Journal of the American Society of Hematology 124 (26), 3896-3904, 2014
Structure and sequence analyses of clustered protocadherins reveal antiparallel interactions that mediate homophilic specificity
JM Nicoludis, SY Lau, CPI Schärfe, DS Marks, WA Weihofen, R Gaudet
Structure 23 (11), 2087-2098, 2015
Structural and functional characterization of the bacterial type III secretion export apparatus
T Dietsche, MT Mebrhatu, MJ Brunner, P Abrusci, J Yan, M Franz-Wachtel, ...
PLoS pathogens 12 (12), 2016
Antiparallel protocadherin homodimers use distinct affinity-and specificity-mediating regions in cadherin repeats 1-4
JM Nicoludis, BE Vogt, AG Green, CPI Schärfe, DS Marks, R Gaudet
Elife 5, e18449, 2016
Genetic variation in human drug-related genes
CPI Schärfe, R Tremmel, M Schwab, O Kohlbacher, DS Marks
Genome medicine 9 (1), 117, 2017
Standards‐based metadata management for molecular simulations
R Grunzke, S Breuers, S Gesing, S Herres‐Pawlis, M Kruse, D Blunk, ...
Concurrency and Computation: Practice and Experience 26 (10), 1744-1759, 2014
From the Desktop to the Grid: conversion of KNIME Workflows to gUSE.
L de la Garza, J Krüger, C Schärfe, M Röttig, S Aiche, K Reinert, ...
IWSG, 2013
The EVcouplings Python framework for coevolutionary sequence analysis
TA Hopf, AG Green, B Schubert, S Mersmann, CPI Schärfe, JB Ingraham, ...
Bioinformatics 35 (9), 1582-1584, 2019
Structure, dynamics and implied gating mechanism of a human cyclic nucleotide-gated channel
Y Gofman, C Schärfe, DS Marks, T Haliloglu, N Ben-Tal
PLoS computational biology 10 (12), 2014
Population-specific design of de-immunized protein biotherapeutics
B Schubert, C Schärfe, P Dönnes, T Hopf, D Marks, O Kohlbacher
PLoS computational biology 14 (3), e1005983, 2018
Sequence co-evolution gives 3D contacts and structures of protein complexes. eLife 3
TA Hopf, CPI Schärfe, J Rodrigues, AG Green, O Kohlbacher, C Sander, ...
Ballaxy: web services for structural bioinformatics
AK Hildebrandt, D Stöckel, NM Fischer, L de la Garza, J Krüger, S Nickels, ...
Bioinformatics 31 (1), 121-122, 2015
ClinVAP: a reporting strategy from variants to therapeutic options
B Sürün, CPI Schärfe, MR Divine, J Heinrich, NC Toussaint, ...
Bioinformatics, 2019
Molecular epidemiology as an effective tool for the diagnosis and control of PRRSV infections in pig farms, illustrated using five cases
T Frey, A Richter, J Skrypski, C Schaerfe, M Hoferer
Development of a pharmacorphore model for pharmacological chaperones targeting mutant trafficking-deficient CNG channels
CPI Schärfe, J Taeger, P Reuter, NM Fischer, J Krüger, B Wissinger, ...
Journal of cheminformatics 5 (1), 1-2, 2013
A Critical Assessment of the Impact of Computational Methods on the Productivity in Pharmaceutical Research and Development
C Schärfe
Competing interests statement
JM Nicoludis, BE Vogt, AG Green, CPI Schärfe, DS Marks, R Gaudet
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Artículos 1–20