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Frederick S Varn
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Longitudinal molecular trajectories of diffuse glioma in adults
FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ...
Nature 576 (7785), 112-120, 2019
3872019
Immunoregulatory functions of VISTA
EC Nowak, JL Lines, FS Varn, J Deng, A Sarde, R Mabaera, A Kuta, ...
Immunological reviews 276 (1), 66-79, 2017
1982017
Glioma progression is shaped by genetic evolution and microenvironment interactions
FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ...
Cell 185 (12), 2184-2199. e16, 2022
1822022
Systematic Pan-Cancer Analysis Reveals Immune Cell Interactions in the Tumor Microenvironment
FS Varn, Y Wang, DW Mullins, S Fiering, C Cheng
Cancer research 77 (6), 1271-1282, 2017
1502017
Hypoxia-induced VISTA promotes the suppressive function of myeloid-derived suppressor cells in the tumor microenvironment
J Deng, J Li, A Sarde, JL Lines, YC Lee, DC Qian, DA Pechenick, ...
Cancer immunology research 7 (7), 1079-1090, 2019
1482019
Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response
KC Johnson, KJ Anderson, ET Courtois, AD Gujar, FP Barthel, FS Varn, ...
Nature genetics 53 (10), 1456-1468, 2021
1242021
Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer
E Kocakavuk, KJ Anderson, FS Varn, KC Johnson, SB Amin, EP Sulman, ...
Nature genetics 53 (7), 1088-1096, 2021
942021
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy
M Gromeier, MC Brown, G Zhang, X Lin, Y Chen, Z Wei, N Beaubier, ...
Nature communications 12 (1), 352, 2021
912021
Perspective of mesenchymal transformation in glioblastoma
Y Kim, FS Varn, SH Park, BW Yoon, HR Park, C Lee, RGW Verhaak, ...
Acta neuropathologica communications 9, 1-20, 2021
812021
Therapeutically targeting tumor microenvironment–mediated drug resistance in estrogen receptor–positive breast cancer
K Shee, W Yang, JW Hinds, RA Hampsch, FS Varn, NA Traphagen, ...
Journal of Experimental Medicine 215 (3), 895-910, 2018
692018
Comparative molecular life history of spontaneous canine and human gliomas
SB Amin, KJ Anderson, CE Boudreau, E Martinez-Ledesma, E Kocakavuk, ...
Cancer cell 37 (2), 243-257. e7, 2020
672020
Adaptive immunity programmes in breast cancer
FS Varn, DW Mullins, H Arias‐Pulido, S Fiering, C Cheng
Immunology 150 (1), 25-34, 2017
632017
Computational immune profiling in lung adenocarcinoma reveals reproducible prognostic associations with implications for immunotherapy
FS Varn, LJ Tafe, CI Amos, C Cheng
Oncoimmunology 7 (6), e1431084, 2018
492018
A P53-deficiency gene signature predicts recurrence risk of patients with early-stage lung adenocarcinoma
Y Zhao, FS Varn, G Cai, F Xiao, CI Amos, C Cheng
Cancer Epidemiology, Biomarkers & Prevention 27 (1), 86-95, 2018
492018
Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
FS Varn, EH Andrews, DW Mullins, C Cheng
Nature communications 7 (1), 10248, 2016
472016
Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells
Y Zhao, R Carter, S Natarajan, FS Varn, DA Compton, C Gawad, C Cheng, ...
BMC Medical Genomics 12, 1-16, 2019
422019
Genomic characterization of six virus-associated cancers identifies changes in the tumor immune microenvironment and altered genetic programs
FS Varn, E Schaafsma, Y Wang, C Cheng
Cancer research 78 (22), 6413-6423, 2018
372018
Multifactorial deep learning reveals pan-cancer genomic tumor clusters with distinct immunogenomic landscape and response to immunotherapy
F Xie, J Zhang, J Wang, A Reuben, W Xu, X Yi, FS Varn, Y Ye, J Cheng, ...
Clinical Cancer Research 26 (12), 2908-2920, 2020
342020
Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy
K White, K Connor, M Meylan, A Bougoüin, M Salvucci, F Bielle, ...
Annals of Oncology 34 (3), 300-314, 2023
312023
A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response to immune checkpoint blockade therapy
FS Varn, Y Wang, C Cheng
OncoImmunology 8 (1), e1513440, 2019
242019
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