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Andrei A. Gilep
Andrei A. Gilep
Department of molecular biotechnology, Institute of bioorganic chemistry NASB
Dirección de correo verificada de iboch.by
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A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1)
O Guryev, RA Carvalho, S Usanov, A Gilep, RW Estabrook
Proceedings of the National Academy of Sciences 100 (25), 14754-14759, 2003
2092003
Athlome Project Consortium: a concerted effort to discover genomic and other “omic” markers of athletic performance
YP Pitsiladis, M Tanaka, N Eynon, C Bouchard, KN North, AG Williams, ...
Physiological genomics, 2016
1462016
Structural insights into aldosterone synthase substrate specificity and targeted inhibition
N Strushkevich, AA Gilep, L Shen, CH Arrowsmith, AM Edwards, ...
Molecular endocrinology 27 (2), 315-324, 2013
1332013
At the crossroads of steroid hormone biosynthesis: the role, substrate specificity and evolutionary development of CYP17
AA Gilep, TA Sushko, SA Usanov
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (1), 200-209, 2011
1292011
Molecular identification of adrenal inner zone antigen as a heme‐binding protein
L Min, NV Strushkevich, IN Harnastai, H Iwamoto, AA Gilep, H Takemori, ...
The FEBS journal 272 (22), 5832-5843, 2005
1192005
Interaction of Apo-cytochrome b5 with Cytochromes P4503A4 and P45017A:  Relevance of Heme Transfer Reactions
OL Guryev, AA Gilep, SA Usanov, RW Estabrook
Biochemistry 40 (16), 5018-5031, 2001
1122001
Probing the interaction of bovine cytochrome P450scc (CYP11A1) with adrenodoxin: evaluating site-directed mutations by molecular modeling
SA Usanov, SE Graham, GI Lepesheva, TN Azeva, NV Strushkevich, ...
Biochemistry 41 (26), 8310-8320, 2002
812002
Involvement of HxuC Outer Membrane Protein in Utilization of Hemoglobin by Haemophilus influenzae
LD Cope, RP Love, SE Guinn, A Gilep, S Usanov, RW Estabrook, Z Hrkal, ...
Infection and immunity 69 (4), 2353-2363, 2001
632001
Adrenodoxin supports reactions catalyzed by microsomal steroidogenic cytochrome P450s
TA Pechurskaya, IN Harnastai, IP Grabovec, AA Gilep, SA Usanov
Biochemical and biophysical research communications 353 (3), 598-604, 2007
512007
Oxidative modification of quercetin by hemeproteins
EM Cherviakovsky, DA Bolibrukh, AV Baranovsky, TM Vlasova, ...
Biochemical and biophysical research communications 342 (2), 459-464, 2006
472006
Protein interactomics based on direct molecular fishing on paramagnetic particles: Practical realization and further SPR validation
AS Ivanov, A Medvedev, P Ershov, A Molnar, Y Mezentsev, E Yablokov, ...
Proteomics 14 (20), 2261-2274, 2014
412014
Human steroid and oxysterol 7α‐hydroxylase CYP 7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants
AV Yantsevich, YV Dichenko, F MacKenzie, DV Mukha, AV Baranovsky, ...
The FEBS journal 281 (6), 1700-1713, 2014
412014
Compound I is the reactive intermediate in the first monooxygenation step during conversion of cholesterol to pregnenolone by cytochrome P450scc: EPR/ENDOR/cryoreduction …
R Davydov, AA Gilep, NV Strushkevich, SA Usanov, BM Hoffman
Journal of the American Chemical Society 134 (41), 17149-17156, 2012
412012
The development of an efficient system for heterologous expression of cytochrome P450s in Escherichia coli using hemA gene co-expression
IN Harnastai, AA Gilep, SA Usanov
Protein expression and purification 46 (1), 47-55, 2006
402006
The role of cytochrome b 5 structural domains in interaction with cytochromes P450
GV Sergeev, AA Gilep, SA Usanov
Biochemistry (Moscow) 79, 406-416, 2014
392014
Structural characterization of human cholesterol 7α-hydroxylase
W Tempel, I Grabovec, F MacKenzie, YV Dichenko, SA Usanov, AA Gilep, ...
Journal of lipid research 55 (9), 1925-1932, 2014
382014
Computer-aided design of aptamers for cytochrome p450
DS Shcherbinin, OV Gnedenko, SA Khmeleva, SA Usanov, AA Gilep, ...
Journal of structural biology 191 (2), 112-119, 2015
372015
Evidence that compound I is the active species in both the hydroxylase and lyase steps by which P450scc converts cholesterol to pregnenolone: EPR/ENDOR/cryoreduction/annealing …
R Davydov, N Strushkevich, D Smil, A Yantsevich, A Gilep, S Usanov, ...
Biochemistry 54 (48), 7089-7097, 2015
362015
Engineering of proteolytically stable NADPH-cytochrome P450 reductase
TA Bonina, AA Gilep, RW Estabrook, SA Usanov
Biochemistry (Moscow) 70, 357-365, 2005
362005
Apo-cytochrome b5 as an indicator of changes in heme accessability:: Preliminary studies with cytochrome P450 3A4
AA Gilep, OL Guryev, SA Usanov, RW Estabrook
Journal of inorganic biochemistry 87 (4), 237-244, 2001
362001
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