Laura Hondebrink
Laura Hondebrink
Dutch Poisons Information Center
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Monitoring new psychoactive substances (NPS) in The Netherlands: data from the drug market and the Poisons Information Centre
L Hondebrink, JJ Nugteren-van Lonkhuyzen, D Van Der Gouwe, TM Brunt
Drug and alcohol dependence 147, 109-115, 2015
Effect fingerprinting of new psychoactive substances (NPS): What can we learn from in vitro data?
L Hondebrink, A Zwartsen, RHS Westerink
Pharmacology & therapeutics 182, 193-224, 2018
Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?
AM Tukker, MW de Groot, FMJ Wijnolts, EEJ Kasteel, L Hondebrink, ...
ALTEX-Alternatives to animal experimentation 33 (3), 261-271, 2016
Pharmacokinetics and pharmacodynamics of 3, 4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug–drug interactions
SJ Rietjens, L Hondebrink, RHS Westerink, J Meulenbelt
Critical reviews in toxicology 42 (10), 854-876, 2012
Neurotoxicity screening of (illicit) drugs using novel methods for analysis of microelectrode array (MEA) recordings
L Hondebrink, AHA Verboven, WS Drega, S Schmeink, M De Groot, ...
Neurotoxicology 55, 1-9, 2016
Pharmacokinetics, pharmacodynamics and toxicology of new psychoactive substances (NPS): 2C-B, 4-fluoroamphetamine and benzofurans
JJ Nugteren-van Lonkhuyzen, AJHP van Riel, TM Brunt, L Hondebrink
Drug and alcohol dependence 157, 18-27, 2015
Neurotoxicity screening of new psychoactive substances (NPS): effects on neuronal activity in rat cortical cultures using microelectrode arrays (MEA)
A Zwartsen, L Hondebrink, RHS Westerink
Neurotoxicology 66, 87-97, 2018
Measuring inhibition of monoamine reuptake transporters by new psychoactive substances (NPS) in real-time using a high-throughput, fluorescence-based assay
A Zwartsen, AHA Verboven, RGDM van Kleef, FMJ Wijnolts, ...
Toxicology in Vitro 45, 60-71, 2017
New psychoactive substances (NPS) in the Netherlands: occurrence in forensic drug samples, consumer drug samples and poisons center exposures between 2013 and 2017
L Hondebrink, JJ Nugteren‐van Lonkhuyzen, CC Hunault, J van den Berg, ...
Addiction 115 (4), 716-725, 2020
Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) recordings
A Zwartsen, T de Korte, P Nacken, DW de Lange, RHS Westerink, ...
Journal of molecular and cellular cardiology 136, 102-112, 2019
Neuropharmacological characterization of the new psychoactive substance methoxetamine
L Hondebrink, EEJ Kasteel, AM Tukker, FMJ Wijnolts, AHA Verboven, ...
Neuropharmacology 123, 1-9, 2017
Fatalities, cerebral hemorrhage, and severe cardiovascular toxicity after exposure to the new psychoactive substance 4-fluoroamphetamine: a prospective cohort study
L Hondebrink, JJ Nugteren–van Lonkhuyzen, SJ Rietjens, TM Brunt, ...
Annals of emergency medicine 71 (3), 294-305, 2018
High concentrations of MDMA (‘ecstasy’) and its metabolite MDA inhibit calcium influx and depolarization-evoked vesicular dopamine release in PC12 cells
L Hondebrink, J Meulenbelt, M Meijer, M van den Berg, RHS Westerink
Neuropharmacology 61 (1-2), 202-208, 2011
Additive inhibition of human α1β2γ2 GABAA receptors by mixtures of commonly used drugs of abuse
L Hondebrink, S Tan, E Hermans, RGDM van Kleef, J Meulenbelt, ...
Neurotoxicology 35, 23-29, 2013
Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse
L Hondebrink, J Meulenbelt, R van Kleef, M van Den Berg, ...
Neurotoxicology 32 (6), 823-827, 2011
Hazard characterization of synthetic cathinones using viability, monoamine reuptake, and neuronal activity assays
A Zwartsen, ME Olijhoek, RHS Westerink, L Hondebrink
Frontiers in neuroscience 14, 9, 2020
Changes in neuronal activity in rat primary cortical cultures induced by illicit drugs and new psychoactive substances (NPS) following prolonged exposure and washout to mimic …
A Zwartsen, L Hondebrink, RHS Westerink
Neurotoxicology 74, 28-39, 2019
Synthetic cathinones and their potential interactions with prescription drugs
RR Contrucci, TM Brunt, F Inan, EJF Franssen, L Hondebrink
Therapeutic Drug Monitoring 42 (1), 75-82, 2020
Acute toxic effects related to 4-fluoroamphetamine
CHW Wijers, RTH van Litsenburg, L Hondebrink, RJM Niesink, EA Croes
The Lancet 389 (10069), 600, 2017
Amphetamine reduces vesicular dopamine content in dexamethasone‐differentiated PC12 cells only following l‐DOPA exposure
L Hondebrink, J Meulenbelt, JG Timmerman, M Van Den Berg, ...
Journal of neurochemistry 111 (2), 624-633, 2009
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