High-resolution crystal structure of an engineered human β2-adrenergic G protein–coupled receptor V Cherezov, DM Rosenbaum, MA Hanson, SGF Rasmussen, FS Thian, ... science 318 (5854), 1258-1265, 2007 | 3572 | 2007 |
Crystal structure of the human β 2 adrenergic G-protein-coupled receptor SGF Rasmussen, HJ Choi, DM Rosenbaum, TS Kobilka, FS Thian, ... Nature 450 (7168), 383-387, 2007 | 2301 | 2007 |
The structure and function of G-protein-coupled receptors DM Rosenbaum, SGF Rasmussen, BK Kobilka Nature 459 (7245), 356-363, 2009 | 2043 | 2009 |
Structure of a nanobody-stabilized active state of the β 2 adrenoceptor SGF Rasmussen, HJ Choi, JJ Fung, E Pardon, P Casarosa, PS Chae, ... Nature 469 (7329), 175-180, 2011 | 1584 | 2011 |
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function DM Rosenbaum, V Cherezov, MA Hanson, SGF Rasmussen, FS Thian, ... science 318 (5854), 1266-1273, 2007 | 1546 | 2007 |
Structure and function of an irreversible agonist-β 2 adrenoceptor complex DM Rosenbaum, C Zhang, JA Lyons, R Holl, D Aragao, DH Arlow, ... Nature 469 (7329), 236-240, 2011 | 780 | 2011 |
Structure and dynamics of the M3 muscarinic acetylcholine receptor AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ... Nature 482 (7386), 552-556, 2012 | 765 | 2012 |
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor MP Bokoch, Y Zou, SGF Rasmussen, CW Liu, R Nygaard, ... Nature 463 (7277), 108-112, 2010 | 505 | 2010 |
Structure-based discovery of β2-adrenergic receptor ligands P Kolb, DM Rosenbaum, JJ Irwin, JJ Fung, BK Kobilka, BK Shoichet Proceedings of the National Academy of Sciences 106 (16), 6843-6848, 2009 | 315 | 2009 |
Insulin resistance in polycystic ovary syndrome: decreased expression of GLUT-4 glucose transporters in adipocytes D Rosenbaum, RS Haber, A Dunaif American Journal of Physiology-Endocrinology And Metabolism 264 (2), E197-E202, 1993 | 282 | 1993 |
High-resolution crystal structure of the human CB1 cannabinoid receptor Z Shao, J Yin, K Chapman, M Grzemska, L Clark, J Wang, ... Nature 540 (7634), 602-606, 2016 | 250 | 2016 |
Efficient and sequence-specific DNA-templated polymerization of peptide nucleic acid aldehydes DM Rosenbaum, DR Liu Journal of the American Chemical Society 125 (46), 13924-13925, 2003 | 173 | 2003 |
Crystal structure of the human sterol transporter ABCG5/ABCG8 JY Lee, LN Kinch, DM Borek, J Wang, J Wang, IL Urbatsch, XS Xie, ... Nature 533 (7604), 561-564, 2016 | 171 | 2016 |
Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant J Yin, JC Mobarec, P Kolb, DM Rosenbaum Nature 519 (7542), 247-250, 2015 | 168 | 2015 |
Structure and ligand-binding mechanism of the human OX 1 and OX 2 orexin receptors J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ... Nature structural & molecular biology 23 (4), 293-299, 2016 | 84 | 2016 |
GF; Thian, FS; Kobilka, TS; Choi, H V Cherezov, DM Rosenbaum, MA Hanson, S Rasmussen J, 2007 | 67 | 2007 |
Ligand modulation of sidechain dynamics in a wild-type human GPCR LD Clark, I Dikiy, K Chapman, KEJ Rödström, J Aramini, MV LeVine, ... Elife 6, e28505, 2017 | 48 | 2017 |
Crystal structures of human orexin 2 receptor bound to the subtype-selective antagonist EMPA R Suno, KT Kimura, T Nakane, K Yamashita, J Wang, T Fujiwara, ... Structure 26 (1), 7-19. e5, 2018 | 40 | 2018 |
Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris L Clark, JA Zahm, R Ali, M Kukula, L Bian, SM Patrie, KH Gardner, ... Journal of biomolecular NMR 62 (3), 239-245, 2015 | 40 | 2015 |
Screening Combinatorial Libraries of de Novo Proteins by Hydrogen− Deuterium Exchange and Electrospray Mass Spectrometry DM Rosenbaum, S Roy, MH Hecht Journal of the American Chemical Society 121 (41), 9509-9513, 1999 | 38 | 1999 |