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Eugen Rempel
Eugen Rempel
Center for Molecular Pathology , Heidelberg University
Verified email at dkfz.de
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Cited by
Cited by
Year
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach
AK Krug, R Kolde, JA Gaspar, E Rempel, NV Balmer, K Meganathan, ...
Archives of toxicology 87, 123-143, 2013
2482013
Integration of light and metabolic signals for stem cell activation at the shoot apical meristem
A Pfeiffer, D Janocha, Y Dong, A Medzihradszky, S Schöne, G Daum, ...
elife 5, e17023, 2016
1832016
Implementing tumor mutational burden (TMB) analysis in routine diagnostics—a primer for molecular pathologists and clinicians
M Allgäuer, J Budczies, P Christopoulos, V Endris, A Lier, E Rempel, ...
Translational lung cancer research 7 (6), 703, 2018
1672018
Size matters: dissecting key parameters for panel‐based tumor mutational burden analysis
I Buchhalter, E Rempel, V Endris, M Allgäuer, O Neumann, AL Volckmar, ...
International journal of cancer 144 (4), 848-858, 2019
1552019
Toxicogenomics directory of chemically exposed human hepatocytes
M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ...
Archives of toxicology 88, 2261-2287, 2014
1492014
Optimizing panel-based tumor mutational burden (TMB) measurement
J Budczies, M Allgäuer, K Litchfield, E Rempel, P Christopoulos, D Kazdal, ...
Annals of Oncology 30 (9), 1496-1506, 2019
1352019
Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells
T Waldmann, E Rempel, NV Balmer, A König, R Kolde, JA Gaspar, ...
Chemical research in toxicology 27 (3), 408-420, 2014
1122014
Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels
V Endris, I Buchhalter, M Allgäuer, E Rempel, A Lier, AL Volckmar, ...
International journal of cancer 144 (9), 2303-2312, 2019
1082019
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors
E Rempel, L Hoelting, T Waldmann, NV Balmer, S Schildknecht, ...
Archives of toxicology 89, 1599-1618, 2015
992015
Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: analysis of the first 3,000 Heidelberg cases
AL Volckmar, J Leichsenring, M Kirchner, P Christopoulos, O Neumann, ...
International Journal of Cancer 145 (3), 649-661, 2019
972019
Harmonization and standardization of panel-based tumor mutational burden measurement: real-world results and recommendations of the quality in pathology study
A Stenzinger, V Endris, J Budczies, S Merkelbach-Bruse, D Kazdal, ...
Journal of Thoracic Oncology 15 (7), 1177-1189, 2020
942020
Variant classification in precision oncology
J Leichsenring, P Horak, S Kreutzfeldt, C Heining, P Christopoulos, ...
International journal of cancer 145 (11), 2996-3010, 2019
942019
Spatial and temporal heterogeneity of panel-based tumor mutational burden in pulmonary adenocarcinoma: separating biology from technical artifacts
D Kazdal, V Endris, M Allgäuer, M Kriegsmann, J Leichsenring, ...
Journal of Thoracic Oncology 14 (11), 1935-1947, 2019
852019
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug …
NV Balmer, S Klima, E Rempel, VN Ivanova, R Kolde, MK Weng, ...
Archives of toxicology 88, 1451-1468, 2014
802014
Motor neurons control blood vessel patterning in the developing spinal cord
P Himmels, I Paredes, H Adler, A Karakatsani, R Luck, HH Marti, ...
Nature communications 8 (1), 14583, 2017
712017
Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma
R Marchan, B Büttner, J Lambert, K Edlund, I Glaeser, M Blaszkewicz, ...
Cancer research 77 (17), 4589-4601, 2017
652017
Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox ukn and STOP-Tox ukk tests
V Shinde, L Hoelting, SP Srinivasan, J Meisig, K Meganathan, S Jagtap, ...
Archives of toxicology 91, 839-864, 2017
612017
Human pluripotent stem cell based developmental toxicity assays for chemical safety screening and systems biology data generation
V Shinde, S Klima, PS Sureshkumar, K Meganathan, S Jagtap, E Rempel, ...
JoVE (Journal of Visualized Experiments), e52333, 2015
572015
Stem cell transcriptome responses and corresponding biomarkers that indicate the transition from adaptive responses to cytotoxicity
T Waldmann, M Grinberg, A Konig, E Rempel, S Schildknecht, M Henry, ...
Chemical research in toxicology 30 (4), 905-922, 2017
442017
RNA-based detection of gene fusions in formalin-fixed and paraffin-embedded solid cancer samples
M Kirchner, O Neumann, AL Volckmar, F Stögbauer, M Allgäuer, D Kazdal, ...
Cancers 11 (9), 1309, 2019
432019
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