Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts S Ghavami, B Yeganeh, AA Zeki, S Shojaei, NJ Kenyon, S Ott, A Samali, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (3 …, 2018 | 126 | 2018 |
Oligomeric Aβ in the monkey brain impacts synaptic integrity and induces accelerated cortical aging D Beckman, S Ott, K Donis-Cox, WG Janssen, E Bliss-Moreau, ... Proceedings of the National Academy of Sciences 116 (52), 26239-26246, 2019 | 82 | 2019 |
SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19 D Beckman, A Bonillas, GB Diniz, S Ott, JW Roh, SR Elizaldi, BA Schmidt, ... Cell reports 41 (5), 2022 | 56 | 2022 |
A novel tau‐based rhesus monkey model of Alzheimer's pathogenesis D Beckman, P Chakrabarty, S Ott, A Dao, E Zhou, WG Janssen, ... Alzheimer's & Dementia 17 (6), 933-945, 2021 | 55 | 2021 |
Intratracheal instillation of pravastatin for the treatment of murine allergic asthma: a lung‐targeted approach to deliver statins AA Zeki, JM Bratt, KY Chang, LM Franzi, S Ott, M Silveria, O Fiehn, ... Physiological reports 3 (5), e12352, 2015 | 37 | 2015 |
Sarcolipin and ubiquitin carboxy-terminal hydrolase 1 mRNAs are over-expressed in skeletal muscles of α-tocopherol deficient mice VT Vasu, S Ott, B Hobson, V Rashidi, S Oommen, CE Cross, K Gohil Free radical research 43 (2), 106-116, 2009 | 28 | 2009 |
Inhibition of myeloperoxidase: Evaluation of 2H-indazoles and 1H-indazolones A Roth, S Ott, KM Farber, TA Palazzo, WE Conrad, MJ Haddadin, ... Bioorganic & medicinal chemistry 22 (22), 6422-6429, 2014 | 27 | 2014 |
Farnesyltransferase inhibition exacerbates eosinophilic inflammation and airway hyperreactivity in mice with experimental asthma: the complex roles of ras GTPase and … JM Bratt, KY Chang, M Rabowsky, LM Franzi, SP Ott, S Filosto, ... The Journal of Immunology 200 (11), 3840-3856, 2018 | 9 | 2018 |
Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection CE Hawes, SR Elizaldi, D Beckman, GB Diniz, Y Shaan Lakshmanappa, ... Journal of neuroinflammation 19 (1), 250, 2022 | 6 | 2022 |
Quantitative assessment of cyanide in cystic fibrosis sputum and its oxidative catabolism by hypochlorous acid JP Eiserich, SP Ott, T Kadir, BM Morrissey, KA Hayakawa, MA La Merrill, ... Free Radical Biology and Medicine 129, 146-154, 2018 | 6 | 2018 |
The fate of inhaled simvastatin in the lungs and systemic circulation AA Zeki, M Elbadawi-Sidhu, S Ott, O Fiehn C79. ADVANCING UNDERSTANDING OF OBSTRUCTIVE LUNG DISEASE: MEDICATIONS AND …, 2017 | 4 | 2017 |
The complex roles of endoplasmic reticulum stress and autophagy in modulating Eotaxin-3 production and secretion from human airway epithelial cells AA Zeki, S Ott, K Sandhu, S Ghavami, NJ Kenyon D33. AIRWAY EPITHELIA ACTIVATION AND RESPONSES TO TREATMENT, A5683-A5683, 2014 | 4 | 2014 |
The mevalonate pathway regulates eotaxin-3 secretion from human airway epithelial cells: a therapeutic role for simvastatin in asthma AA Zeki, S Ott, K Sandhu, R Wu JOURNAL OF INVESTIGATIVE MEDICINE 62 (1), 197-198, 2014 | 2 | 2014 |
Deep analysis of CD4 T cells in the rhesus CNS during SIV infection SR Elizaldi, A Verma, ZM Ma, S Ott, D Rajasundaram, CE Hawes, ... PLoS Pathogens 19 (12), e1011844, 2023 | 1 | 2023 |
The organic anion transporter polypeptides (OATP) in the mouse lung and human airway epithelium: important molecular targets in the development of inhaled statins AA Zeki, S Ott, K Gohil A33. ASTHMA MECHANISMS, A1330-A1330, 2018 | 1 | 2018 |
Quantitative analysis of synaptic pathology and neuroinflammation: an initial study in a female rhesus monkey model of the “synaptic” phase of Alzheimer’s disease D Beckman, K Donis-Cox, S Ott, M Roberts, L Novik, WG Janssen, ... bioRxiv, 251025, 2018 | 1 | 2018 |
Surfactant Protein-D (SP-D) Is A Lung Specific Regulator of Group 2 Innate Lymphoid Cells (ILC2) CH Flayer, MQ Ge, PB Kovacs, S Ott, A Haczku Journal of Allergy and Clinical Immunology 139 (2), AB15, 2017 | 1 | 2017 |
Metabolomic and lipidomic analyses reveal that inhalation of statins affects pulmonary and systemic metabolism in the rhesus macaque non-human primate model AA Zeki, M Elbadawi, S Ott, O Fiehn, LA Miller, A Haczku A31. ASTHMA THERAPY: GLUCOCORTICOIDS AND BEYOND, A1302-A1302, 2016 | 1 | 2016 |
The Mevalonate Pathway Regulates Eotaxin-3 Secretion from Human Airway Epithelial Cells: A Therapeutic Role for Simvastatin in Asthma K Sandhu, S Ott, R Wu, AA Zeki Journal of Investigative Medicine 62 (1), 257-257, 2014 | 1 | 2014 |
Chronic SIV-induced neuroinflammation disrupts CCR7+ CD4+ T cell immunosurveillance in the rhesus macaque brain SR Elizaldi, CE Hawes, A Verma, YS Lakshmanappa, AR Dinasarapu, ... The Journal of Clinical Investigation, 2024 | | 2024 |