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Sean Ott
Sean Ott
Verified email at ucdavis.edu
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Year
Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts
S Ghavami, B Yeganeh, AA Zeki, S Shojaei, NJ Kenyon, S Ott, A Samali, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (3 …, 2018
1262018
Oligomeric Aβ in the monkey brain impacts synaptic integrity and induces accelerated cortical aging
D Beckman, S Ott, K Donis-Cox, WG Janssen, E Bliss-Moreau, ...
Proceedings of the National Academy of Sciences 116 (52), 26239-26246, 2019
822019
SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19
D Beckman, A Bonillas, GB Diniz, S Ott, JW Roh, SR Elizaldi, BA Schmidt, ...
Cell reports 41 (5), 2022
562022
A novel tau‐based rhesus monkey model of Alzheimer's pathogenesis
D Beckman, P Chakrabarty, S Ott, A Dao, E Zhou, WG Janssen, ...
Alzheimer's & Dementia 17 (6), 933-945, 2021
552021
Intratracheal instillation of pravastatin for the treatment of murine allergic asthma: a lung‐targeted approach to deliver statins
AA Zeki, JM Bratt, KY Chang, LM Franzi, S Ott, M Silveria, O Fiehn, ...
Physiological reports 3 (5), e12352, 2015
372015
Sarcolipin and ubiquitin carboxy-terminal hydrolase 1 mRNAs are over-expressed in skeletal muscles of α-tocopherol deficient mice
VT Vasu, S Ott, B Hobson, V Rashidi, S Oommen, CE Cross, K Gohil
Free radical research 43 (2), 106-116, 2009
282009
Inhibition of myeloperoxidase: Evaluation of 2H-indazoles and 1H-indazolones
A Roth, S Ott, KM Farber, TA Palazzo, WE Conrad, MJ Haddadin, ...
Bioorganic & medicinal chemistry 22 (22), 6422-6429, 2014
272014
Farnesyltransferase inhibition exacerbates eosinophilic inflammation and airway hyperreactivity in mice with experimental asthma: the complex roles of ras GTPase and …
JM Bratt, KY Chang, M Rabowsky, LM Franzi, SP Ott, S Filosto, ...
The Journal of Immunology 200 (11), 3840-3856, 2018
92018
Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection
CE Hawes, SR Elizaldi, D Beckman, GB Diniz, Y Shaan Lakshmanappa, ...
Journal of neuroinflammation 19 (1), 250, 2022
62022
Quantitative assessment of cyanide in cystic fibrosis sputum and its oxidative catabolism by hypochlorous acid
JP Eiserich, SP Ott, T Kadir, BM Morrissey, KA Hayakawa, MA La Merrill, ...
Free Radical Biology and Medicine 129, 146-154, 2018
62018
The fate of inhaled simvastatin in the lungs and systemic circulation
AA Zeki, M Elbadawi-Sidhu, S Ott, O Fiehn
C79. ADVANCING UNDERSTANDING OF OBSTRUCTIVE LUNG DISEASE: MEDICATIONS AND …, 2017
42017
The complex roles of endoplasmic reticulum stress and autophagy in modulating Eotaxin-3 production and secretion from human airway epithelial cells
AA Zeki, S Ott, K Sandhu, S Ghavami, NJ Kenyon
D33. AIRWAY EPITHELIA ACTIVATION AND RESPONSES TO TREATMENT, A5683-A5683, 2014
42014
The mevalonate pathway regulates eotaxin-3 secretion from human airway epithelial cells: a therapeutic role for simvastatin in asthma
AA Zeki, S Ott, K Sandhu, R Wu
JOURNAL OF INVESTIGATIVE MEDICINE 62 (1), 197-198, 2014
22014
Deep analysis of CD4 T cells in the rhesus CNS during SIV infection
SR Elizaldi, A Verma, ZM Ma, S Ott, D Rajasundaram, CE Hawes, ...
PLoS Pathogens 19 (12), e1011844, 2023
12023
The organic anion transporter polypeptides (OATP) in the mouse lung and human airway epithelium: important molecular targets in the development of inhaled statins
AA Zeki, S Ott, K Gohil
A33. ASTHMA MECHANISMS, A1330-A1330, 2018
12018
Quantitative analysis of synaptic pathology and neuroinflammation: an initial study in a female rhesus monkey model of the “synaptic” phase of Alzheimer’s disease
D Beckman, K Donis-Cox, S Ott, M Roberts, L Novik, WG Janssen, ...
bioRxiv, 251025, 2018
12018
Surfactant Protein-D (SP-D) Is A Lung Specific Regulator of Group 2 Innate Lymphoid Cells (ILC2)
CH Flayer, MQ Ge, PB Kovacs, S Ott, A Haczku
Journal of Allergy and Clinical Immunology 139 (2), AB15, 2017
12017
Metabolomic and lipidomic analyses reveal that inhalation of statins affects pulmonary and systemic metabolism in the rhesus macaque non-human primate model
AA Zeki, M Elbadawi, S Ott, O Fiehn, LA Miller, A Haczku
A31. ASTHMA THERAPY: GLUCOCORTICOIDS AND BEYOND, A1302-A1302, 2016
12016
The Mevalonate Pathway Regulates Eotaxin-3 Secretion from Human Airway Epithelial Cells: A Therapeutic Role for Simvastatin in Asthma
K Sandhu, S Ott, R Wu, AA Zeki
Journal of Investigative Medicine 62 (1), 257-257, 2014
12014
Chronic SIV-induced neuroinflammation disrupts CCR7CD4+ T cell immunosurveillance in the rhesus macaque brain
SR Elizaldi, CE Hawes, A Verma, YS Lakshmanappa, AR Dinasarapu, ...
The Journal of Clinical Investigation, 2024
2024
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